EA028026B1 - Противовирусное соединение, содержащая его фармацевтическая композиция и способ лечения - Google Patents
Противовирусное соединение, содержащая его фармацевтическая композиция и способ лечения Download PDFInfo
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- EA028026B1 EA028026B1 EA201492002A EA201492002A EA028026B1 EA 028026 B1 EA028026 B1 EA 028026B1 EA 201492002 A EA201492002 A EA 201492002A EA 201492002 A EA201492002 A EA 201492002A EA 028026 B1 EA028026 B1 EA 028026B1
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| KR101835474B1 (ko) | 2010-11-17 | 2018-03-08 | 길리애드 파마셋 엘엘씨 | 항바이러스 화합물 |
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| EA201690473A1 (ru) | 2013-08-27 | 2017-03-31 | ГАЙЛИД ФАРМАССЕТ ЭлЭлСи | Комбинированный состав двух противовирусных соединений |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| TWI679203B (zh) | 2014-06-11 | 2019-12-11 | 美商基利法瑪席特有限責任公司 | 製備抗病毒化合物之方法 |
| WO2016004166A1 (en) * | 2014-07-02 | 2016-01-07 | Xavier University Of Louisiana | Boron-based prodrug strategy for increased bioavailability and lower-dosage requirements for drug molecules containing at least one phenol (or aromatic hydroxyl) group |
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| KR102398439B1 (ko) | 2016-03-07 | 2022-05-16 | 이난타 파마슈티칼스, 인코포레이티드 | B형 간염 항바이러스제 |
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| WO2018006811A1 (zh) * | 2016-07-08 | 2018-01-11 | 深圳市塔吉瑞生物医药有限公司 | 一种取代的咪唑基化合物及其药物组合物 |
| CN106220639A (zh) * | 2016-07-22 | 2016-12-14 | 上海众强药业有限公司 | 一种维帕他韦中间体新晶型 |
| CN107573380B (zh) * | 2016-11-30 | 2020-06-02 | 上海博志研新药物技术有限公司 | 维帕他韦中间体、制备方法及应用 |
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| CN107501280A (zh) * | 2017-09-05 | 2017-12-22 | 安徽华昌高科药业有限公司 | 一种维帕他韦的合成方法 |
| RU2020116571A (ru) | 2017-12-07 | 2021-11-22 | Эмори Юниверсити | N4-гидроксицитидин и производные и связанные с этим противовирусные применения |
| EP3883570A4 (en) | 2018-11-21 | 2022-07-13 | Enanta Pharmaceuticals, Inc. | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS |
| CN111018870B (zh) * | 2019-11-29 | 2021-07-23 | 南京正济医药研究有限公司 | 一种维帕他韦中间体的制备方法 |
| US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| WO2022040058A1 (en) * | 2020-08-18 | 2022-02-24 | Merck Sharp & Dohme Corp. | Cyclopentapyrrole orexin receptor agonists |
| US12274700B1 (en) | 2020-10-30 | 2025-04-15 | Accencio LLC | Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors |
| AU2022279234B2 (en) * | 2021-05-21 | 2025-08-28 | Gilead Sciences, Inc. | Pentacyclic derivatives as zika virus inhibitors |
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| US9233974B2 (en) * | 2012-12-21 | 2016-01-12 | Gilead Sciences, Inc. | Antiviral compounds |
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- 2013-05-15 PL PL17160683T patent/PL3239153T3/pl unknown
- 2013-05-15 PL PL13726936T patent/PL2850085T3/pl unknown
- 2013-05-15 MX MX2014013660A patent/MX362060B/es active IP Right Grant
- 2013-05-15 EP EP13726936.1A patent/EP2850085B1/en active Active
- 2013-05-15 EA EA201790963A patent/EA034749B1/ru unknown
- 2013-12-05 IN IN2459MUN2014 patent/IN2014MN02459A/en unknown
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2014
- 2014-06-26 US US14/316,573 patent/US20140316144A1/en not_active Abandoned
- 2014-11-11 IL IL235645A patent/IL235645A0/en active IP Right Grant
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2015
- 2015-10-28 US US14/925,203 patent/US9682989B2/en active Active
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2017
- 2017-05-09 US US15/590,846 patent/US20170342085A1/en not_active Abandoned
- 2017-06-26 JP JP2017124206A patent/JP6408656B2/ja active Active
- 2017-10-20 AU AU2017248566A patent/AU2017248566A1/en not_active Abandoned
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2018
- 2018-04-10 HK HK18104656.7A patent/HK1245262B/en unknown
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2019
- 2019-06-24 AU AU2019204423A patent/AU2019204423A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010096777A1 (en) * | 2009-02-23 | 2010-08-26 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| WO2012068234A2 (en) * | 2010-11-17 | 2012-05-24 | Gilead Sciences, Inc. | Antiviral compounds |
Non-Patent Citations (1)
| Title |
|---|
| XIAOFAN ZHENG; THOMAS W. HUDYMA; SCOTT W. MARTIN; CARL BERGSTROM; MIN DING; FENG HE; JEFFREY ROMINE; MICHAEL A. POSS; JOHN F. KADO: "Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 21, no. 10, 17 March 2011 (2011-03-17), AMSTERDAM, NL, pages 2925 - 2929, XP028199550, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2011.03.067 * |
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