EA024755B1 - Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения - Google Patents

Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения Download PDF

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EA024755B1
EA024755B1 EA201291010A EA201291010A EA024755B1 EA 024755 B1 EA024755 B1 EA 024755B1 EA 201291010 A EA201291010 A EA 201291010A EA 201291010 A EA201291010 A EA 201291010A EA 024755 B1 EA024755 B1 EA 024755B1
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Eurasian Patent Office
Prior art keywords
polypeptide
amino acid
proline
alanine
acid sequence
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EA201291010A
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English (en)
Russian (ru)
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EA201291010A1 (ru
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Арне Скерра
Ули Биндер
Мартин Шлапши
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ИксЭль-ПРОТЕИН ГМБХ
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Publication of EA201291010A1 publication Critical patent/EA201291010A1/ru
Publication of EA024755B1 publication Critical patent/EA024755B1/ru

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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
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EA201291010A 2010-05-21 2011-05-20 Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения EA024755B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10163564 2010-05-21
US201061428016P 2010-12-29 2010-12-29
PCT/EP2011/058307 WO2011144756A1 (en) 2010-05-21 2011-05-20 Biosynthetic proline/alanine random coil polypeptides and their uses

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EA201291010A1 EA201291010A1 (ru) 2013-09-30
EA024755B1 true EA024755B1 (ru) 2016-10-31

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US (3) US9221882B2 (https=)
EP (2) EP2571510B1 (https=)
JP (2) JP5828889B2 (https=)
KR (1) KR101872541B1 (https=)
CN (2) CN102883734B (https=)
AU (1) AU2011254564B2 (https=)
BR (1) BR112012029577B1 (https=)
CA (1) CA2794614C (https=)
DK (1) DK2571510T3 (https=)
EA (1) EA024755B1 (https=)
ES (1) ES2691642T3 (https=)
LT (1) LT2571510T (https=)
MX (2) MX357674B (https=)
NZ (1) NZ602522A (https=)
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SG (1) SG185440A1 (https=)
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MX344559B (es) 2008-04-29 2016-12-20 Ascendis Pharma As Compuestos de hormona de crecimiento humana recombinante unidos al peg.
MX337432B (es) 2009-12-15 2016-03-04 Ascendis Pharma As Composicion de la hormona del crecimiento seca enlazada transitoriamente a un portador del polimero.
US9221882B2 (en) 2010-05-21 2015-12-29 Technische Universitat Munchen Biosynthetic proline/alanine random coil polypeptides and their uses
AU2012296951B2 (en) * 2011-08-12 2016-09-15 Ascendis Pharma A/S Protein carrier-linked prodrugs
JP6355563B2 (ja) * 2012-02-27 2018-07-11 アムニクス オペレーティング インコーポレイテッド Ｘｔｅｎ共役組成物およびそれを製造する方法
CN108686203A (zh) 2012-04-04 2018-10-23 哈洛齐梅公司 使用抗透明质酸剂和肿瘤靶向紫杉烷的组合疗法
WO2014114660A1 (en) * 2013-01-22 2014-07-31 Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
JP6259208B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 ヒアルロン酸産生促進剤
JP6259207B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 エラスチン産生促進剤
JP6259209B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 コラーゲン産生促進剤
EP3068438A1 (en) 2013-11-11 2016-09-21 Ascendis Pharma Relaxin Division A/S Relaxin prodrugs
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