DOP2006000285A - Derivados de bencimidazol sustituidos con cromano - Google Patents
Derivados de bencimidazol sustituidos con cromanoInfo
- Publication number
- DOP2006000285A DOP2006000285A DO2006000285A DO2006000285A DOP2006000285A DO P2006000285 A DOP2006000285 A DO P2006000285A DO 2006000285 A DO2006000285 A DO 2006000285A DO 2006000285 A DO2006000285 A DO 2006000285A DO P2006000285 A DOP2006000285 A DO P2006000285A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- compounds
- disease
- pharmaceutically acceptable
- acceptable salt
- ulcer
- Prior art date
Links
- VZWXIQHBIQLMPN-UHFFFAOYSA-N chromane Chemical group C1=CC=C2CCCOC2=C1 VZWXIQHBIQLMPN-UHFFFAOYSA-N 0.000 title 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 201000006549 dyspepsia Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000019505 Deglutition disease Diseases 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 206010019375 Helicobacter infections Diseases 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 206010030216 Oesophagitis Diseases 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 206010039424 Salivary hypersecretion Diseases 0.000 abstract 1
- 208000008630 Sialorrhea Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 206010042496 Sunburn Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000010643 digestive system disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000006881 esophagitis Diseases 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 208000029493 gastroesophageal disease Diseases 0.000 abstract 1
- 208000018685 gastrointestinal system disease Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
- 208000009935 visceral pain Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75218105P | 2005-12-19 | 2005-12-19 | |
| US80294406P | 2006-05-23 | 2006-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2006000285A true DOP2006000285A (es) | 2007-07-31 |
Family
ID=37912450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2006000285A DOP2006000285A (es) | 2005-12-19 | 2006-12-18 | Derivados de bencimidazol sustituidos con cromano |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7723321B2 (enExample) |
| EP (1) | EP1963311B1 (enExample) |
| JP (1) | JP4481344B2 (enExample) |
| KR (1) | KR101088247B1 (enExample) |
| CN (2) | CN101341149B (enExample) |
| AR (1) | AR058120A1 (enExample) |
| AT (1) | ATE471319T1 (enExample) |
| BR (2) | BRPI0620081B8 (enExample) |
| CA (1) | CA2631880C (enExample) |
| DE (1) | DE602006014996D1 (enExample) |
| DO (1) | DOP2006000285A (enExample) |
| ES (1) | ES2345726T3 (enExample) |
| GT (1) | GT200600514A (enExample) |
| NL (1) | NL2000371C2 (enExample) |
| PE (1) | PE20071182A1 (enExample) |
| TW (1) | TW200732326A (enExample) |
| UY (1) | UY30043A1 (enExample) |
| WO (1) | WO2007072146A1 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE539063T1 (de) * | 2007-06-26 | 2012-01-15 | Sanofi Sa | Regioselektive, kupferkatalysierte synthese von benzimidazolen und azabenzimidazolen |
| MX2012000275A (es) * | 2009-07-09 | 2012-02-08 | Raqualia Pharma Inc | Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal. |
| KR101472686B1 (ko) | 2013-07-09 | 2014-12-16 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 제조방법 |
| KR102084185B1 (ko) | 2013-08-29 | 2020-03-04 | 주식회사 대웅제약 | 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법 |
| KR102129842B1 (ko) * | 2013-10-02 | 2020-07-06 | 주식회사 대웅제약 | 술포닐인돌 유도체 및 이의 제조방법 |
| JP6502939B2 (ja) | 2013-11-22 | 2019-04-17 | シーエル バイオサイエンシズ リミティド ライアビリティ カンパニー | 骨粗鬆症の処置及び予防のためのガストリン拮抗薬 |
| CN105440016B (zh) * | 2014-08-11 | 2018-08-31 | 江苏柯菲平医药股份有限公司 | 吲哚、氮杂吲哚类衍生物、其制备方法及其在医药上的应用 |
| KR101684053B1 (ko) * | 2015-01-20 | 2016-12-08 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법 |
| KR101613245B1 (ko) | 2015-04-27 | 2016-04-18 | 주식회사 대웅제약 | 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| HK1252562A1 (zh) * | 2015-06-08 | 2019-05-31 | Hk Inno.N Corporation | 苯并咪唑衍生物用於夜间酸突破的用途 |
| KR101769204B1 (ko) * | 2015-08-04 | 2017-08-17 | 씨제이헬스케어 주식회사 | 크로마놀 유도체의 신규한 제조방법 |
| KR101777971B1 (ko) | 2016-07-05 | 2017-09-12 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도 |
| KR101829685B1 (ko) * | 2016-07-28 | 2018-02-19 | 씨제이헬스케어 주식회사 | 안정성 및 용해도가 개선된 주사용 조성물 |
| KR101829705B1 (ko) * | 2016-09-21 | 2018-02-19 | 씨제이헬스케어 주식회사 | 안정성이 향상된 주사용 조성물 |
| KR101829706B1 (ko) * | 2016-09-21 | 2018-02-19 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 산부가염 |
| EP3559051B1 (en) * | 2016-12-20 | 2021-03-24 | ExxonMobil Chemical Patents Inc. | Polymerization process |
| KR101960357B1 (ko) * | 2016-12-26 | 2019-03-20 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체를 포함하는 신규한 제제 |
| KR102233456B1 (ko) * | 2017-05-31 | 2021-03-29 | 주식회사 대웅제약 | 4-메톡시피롤 유도체의 중간체 제조 방법 |
| KR102262743B1 (ko) * | 2017-07-07 | 2021-06-09 | 에이치케이이노엔 주식회사 | 주사용 조성물 |
| KR20190057569A (ko) | 2017-11-20 | 2019-05-29 | 제일약품주식회사 | 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도 |
| TWI676477B (zh) * | 2017-12-05 | 2019-11-11 | 南韓商Ｃｊ醫藥健康股份有限公司 | 苯并咪唑衍生物用於夜間酸突破的用途 |
| JOP20190198A1 (ar) * | 2018-08-28 | 2020-02-28 | Hk Inno N Corp | تركيبة صيدلانية تشتمل على عامل مضاد للصفيحات ومثبط إفراز حمض معدي |
| JOP20190201A1 (ar) * | 2018-08-29 | 2020-02-29 | Hk Inno N Corp | تركيبة لاستئصال الملوية البوابية |
| CN109320485B (zh) * | 2018-12-02 | 2021-06-18 | 江苏慧聚药业有限公司 | 合成特戈拉赞手性醇的方法 |
| EP3927340B1 (en) * | 2019-02-18 | 2025-09-03 | HK inno.N Corporation | Pharmaceutical composition comprising tegoprazan for preventing the recurrence of gastroesophageal reflux disease |
| CN112851646B (zh) * | 2019-11-12 | 2023-06-13 | 中国医学科学院药物研究所 | 特戈拉赞的制备方法 |
| UY39094A (es) * | 2020-02-27 | 2021-07-30 | Hk Inno N Corp | Composición farmacéutica que comprende compuesto derivado de bencimidazol |
| CN111303131B (zh) * | 2020-03-19 | 2021-06-04 | 江苏慧聚药业有限公司 | 特戈拉赞(Tegoprazan)类似物及其合成方法 |
| MX2022012848A (es) | 2020-04-13 | 2023-01-16 | Hk Inno N Corp | Composicion farmaceutica que comprende compuesto derivado de benzimidazol. |
| CN114249694B (zh) * | 2020-09-22 | 2025-06-17 | 浙江四维医药科技有限公司 | 一种特格拉赞中间体的制备方法 |
| UY39479A (es) | 2020-10-23 | 2021-11-30 | Hk Inno N Corp | Comprimido de desintegración oral que comprende compuesto derivado de benzimidazol y procedimiento de preparación del mismo |
| CN112358450A (zh) * | 2020-11-19 | 2021-02-12 | 南京艾康生物科技有限公司 | 一种4-(苄氧基)-2-甲基-1H-苯并[d]咪唑-6-羧酸的合成方法 |
| KR20220141700A (ko) | 2021-04-13 | 2022-10-20 | 에이치케이이노엔 주식회사 | 벤즈이미다졸 유도체 화합물을 포함하는 약학적 조성물 |
| CN113527272B (zh) * | 2021-08-06 | 2023-07-21 | 西安淳甄新材料有限公司 | 一种特戈拉赞的合成方法 |
| US20250051376A1 (en) * | 2021-12-08 | 2025-02-13 | Pharmgen Science, Inc. | Benzimidazole derivative compounds and use thereof |
| KR102708701B1 (ko) * | 2021-12-27 | 2024-09-24 | 에이치케이이노엔 주식회사 | 벤즈이미다졸 유도체의 제조방법 |
| CN114805317A (zh) * | 2022-05-20 | 2022-07-29 | 江苏威奇达药业有限公司 | 一种特戈拉赞的制备方法 |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| KR20240028127A (ko) | 2022-08-24 | 2024-03-05 | 위더스제약주식회사 | 테고프라잔 고체분산체 조성물 |
| WO2024045255A1 (zh) * | 2022-08-30 | 2024-03-07 | 上海皓元医药股份有限公司 | 一种特戈拉赞晶型b及其制备方法 |
| WO2024087156A1 (zh) * | 2022-10-28 | 2024-05-02 | 深圳市华先医药科技有限公司 | 4-羟基-n,n,2-三甲基苯并咪唑-6-甲酰胺的可放大生产方法 |
| WO2024087155A1 (zh) * | 2022-10-28 | 2024-05-02 | 深圳市华先医药科技有限公司 | 一种合成4-羟基-n,n,2-三甲基苯并咪唑-6-甲酰胺的方法 |
| CN116253685B (zh) * | 2022-12-30 | 2024-12-10 | 成都安满生物医药科技有限公司 | 一种特戈拉赞中间体的制备方法 |
| KR20240109898A (ko) | 2023-01-05 | 2024-07-12 | 위더스제약주식회사 | 무정형 테고프라잔 고체분산체 |
| KR102638900B1 (ko) | 2023-01-27 | 2024-02-21 | 스마트바이오팜 주식회사 | 테고프라잔 중간체를 제조하는 방법 및 이에 사용되는 신규 중간체 |
| KR20240118377A (ko) | 2023-01-27 | 2024-08-05 | 스마트바이오팜 주식회사 | 테고프라잔 중간체를 제조하는 방법 및 이에 사용되는 신규 중간체 |
| WO2024171128A1 (en) * | 2023-02-18 | 2024-08-22 | Lee Pharma Limited | Stable amorphous form of potassium-competitive acid blocker and process for the preparation thereof |
| KR20240131641A (ko) | 2023-02-24 | 2024-09-02 | 엠에프씨 주식회사 | 신규 테고프라잔의 염 결정형 및 이의 용매화물 결정형, 및 이들의 제조방법 |
| KR102715562B1 (ko) * | 2023-03-16 | 2024-10-11 | (주) 에프엔지리서치 | 테고프라잔의 신규 염 및 이의 제조 방법 |
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| CN116621821A (zh) * | 2023-05-29 | 2023-08-22 | 宙晟智维生命科学(上海)有限公司 | 一种无定形的苯并咪唑基化合物及固体分散体 |
| KR20240171624A (ko) | 2023-05-31 | 2024-12-09 | 권대길 | 치환된 벤즈이미다졸의 결정형 및 이의 제조방법 |
| CN116715660A (zh) * | 2023-06-14 | 2023-09-08 | 上海柏狮生物科技有限公司 | 一种特格拉赞的无定型物及其制备方法 |
| CN117024417A (zh) * | 2023-06-27 | 2023-11-10 | 上海柏狮生物科技有限公司 | 一种特格拉赞的制备方法 |
| CN116789654A (zh) * | 2023-07-10 | 2023-09-22 | 杭州小蓓医药科技有限公司 | 一种特戈拉赞的制备方法 |
| WO2025037242A1 (en) * | 2023-08-14 | 2025-02-20 | Ami Lifesciences Private Limited | Solid forms of tegoprazan and process thereof |
| KR102689851B1 (ko) | 2023-09-26 | 2024-07-30 | 스마트바이오팜 주식회사 | 테고프라잔 중간체를 제조하는 방법 및 이에 사용되는 신규 중간체 |
| WO2025095097A1 (en) * | 2023-11-01 | 2025-05-08 | Raqualia Pharma Inc. | Process for producing benzimidazole compound |
| KR20250066641A (ko) | 2023-11-07 | 2025-05-14 | 엠에프씨 주식회사 | 테고프라잔 말리에이트염 1수화물 결정형 및 이의 제조방법 |
| CN117903097A (zh) * | 2024-01-04 | 2024-04-19 | 浙江永太科技股份有限公司 | 一种特戈拉赞关键中间体母液料的回收方法 |
| KR20250118583A (ko) | 2024-01-30 | 2025-08-06 | 진양제약주식회사 | 테고프라잔을 포함하는 제약 조성물 |
| KR102825970B1 (ko) | 2024-02-16 | 2025-06-26 | 스마트바이오팜 주식회사 | 테고프라잔 중간체를 제조하는 방법 및 이에 사용되는 신규 중간체 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8604566D0 (sv) * | 1986-10-27 | 1986-10-27 | Haessle Ab | Novel compunds |
| US5444775A (en) | 1993-11-09 | 1995-08-22 | Tobish; John J. | Telephone key selection aid |
| SE9602286D0 (sv) * | 1996-06-10 | 1996-06-10 | Astra Ab | New compounds |
| GB9914022D0 (en) | 1999-06-17 | 1999-08-18 | Zeneca Ltd | Chemical compounds |
| AR043063A1 (es) * | 2002-12-13 | 2005-07-13 | Altana Pharma Ag | Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas |
| AR049168A1 (es) * | 2004-05-18 | 2006-07-05 | Altana Pharma Ag | Derivados de benzimidazol |
| CA2608582A1 (en) * | 2005-06-14 | 2006-12-21 | Pfizer Inc. | Chromane substituted benzimidazole derivatives as acid pump antagonists |
-
2006
- 2006-12-06 JP JP2008546663A patent/JP4481344B2/ja active Active
- 2006-12-06 CA CA2631880A patent/CA2631880C/en active Active
- 2006-12-06 CN CN2006800479255A patent/CN101341149B/zh active Active
- 2006-12-06 WO PCT/IB2006/003605 patent/WO2007072146A1/en not_active Ceased
- 2006-12-06 BR BRPI0620081A patent/BRPI0620081B8/pt active IP Right Grant
- 2006-12-06 BR BR122020004679-1A patent/BR122020004679B1/pt not_active IP Right Cessation
- 2006-12-06 DE DE602006014996T patent/DE602006014996D1/de active Active
- 2006-12-06 ES ES06831708T patent/ES2345726T3/es active Active
- 2006-12-06 EP EP06831708A patent/EP1963311B1/en active Active
- 2006-12-06 KR KR1020087017466A patent/KR101088247B1/ko active Active
- 2006-12-06 CN CN2011101399640A patent/CN102321077A/zh active Pending
- 2006-12-06 AT AT06831708T patent/ATE471319T1/de not_active IP Right Cessation
- 2006-12-13 NL NL2000371A patent/NL2000371C2/nl not_active IP Right Cessation
- 2006-12-18 DO DO2006000285A patent/DOP2006000285A/es unknown
- 2006-12-18 PE PE2006001625A patent/PE20071182A1/es not_active Application Discontinuation
- 2006-12-18 TW TW095147456A patent/TW200732326A/zh unknown
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- 2006-12-19 UY UY30043A patent/UY30043A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2631880A1 (en) | 2007-06-28 |
| JP2009520017A (ja) | 2009-05-21 |
| WO2007072146A1 (en) | 2007-06-28 |
| TW200732326A (en) | 2007-09-01 |
| HK1125368A1 (en) | 2009-08-07 |
| CN101341149A (zh) | 2009-01-07 |
| ES2345726T3 (es) | 2010-09-30 |
| UY30043A1 (es) | 2007-07-31 |
| NL2000371C2 (nl) | 2007-09-06 |
| JP4481344B2 (ja) | 2010-06-16 |
| KR101088247B1 (ko) | 2011-11-30 |
| ATE471319T1 (de) | 2010-07-15 |
| GT200600514A (es) | 2007-07-17 |
| KR20080080195A (ko) | 2008-09-02 |
| CN101341149B (zh) | 2011-06-08 |
| BRPI0620081B8 (pt) | 2021-05-25 |
| US20070142448A1 (en) | 2007-06-21 |
| BRPI0620081A2 (pt) | 2011-11-01 |
| BRPI0620081B1 (pt) | 2020-10-20 |
| CN102321077A (zh) | 2012-01-18 |
| CA2631880C (en) | 2011-03-29 |
| US7723321B2 (en) | 2010-05-25 |
| EP1963311A1 (en) | 2008-09-03 |
| DE602006014996D1 (de) | 2010-07-29 |
| BR122020004679B1 (pt) | 2021-09-21 |
| EP1963311B1 (en) | 2010-06-16 |
| NL2000371A1 (nl) | 2007-06-20 |
| AR058120A1 (es) | 2008-01-23 |
| PE20071182A1 (es) | 2008-02-07 |
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