UY30043A1 - Derivados de bencimidazol sustituidos con cromano - Google Patents

Derivados de bencimidazol sustituidos con cromano

Info

Publication number
UY30043A1
UY30043A1 UY30043A UY30043A UY30043A1 UY 30043 A1 UY30043 A1 UY 30043A1 UY 30043 A UY30043 A UY 30043A UY 30043 A UY30043 A UY 30043A UY 30043 A1 UY30043 A1 UY 30043A1
Authority
UY
Uruguay
Prior art keywords
compounds
disease
pharmaceutically acceptable
acceptable salt
ulcer
Prior art date
Application number
UY30043A
Other languages
English (en)
Inventor
Takeshi Hanazawa
Hiroki Koike
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37912450&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30043(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of UY30043A1 publication Critical patent/UY30043A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Esta invención se refiere a compuestos de fórmula I, o una de sus sales farmacéuticamente aceptable, en la que A, B, X, R1, R2, R3, R4, R5, R6, R7 y R8 son cada uno de ellos como se ha descrito en esta memoria, o un a sal farmacéuticamente aceptable, y composiciones que contienen tales compuestos y la utilización de tales compuestos en el tratamiento de un estado mediado por la actividad antagonista de la bomba de ácido, tales como, pero sin limitarse a ellos, enfermedad gastrointestinal, enfermedad gastroesofágica, enfermedad de reflijo gastroesofágico (GERD), úlcera péptica, úlcera gástrica, úlcera de duodeno, úlceras inducidas por NSAID, gastritis, infección por Helicobacter pylori, dispepsia funcional, síndorme de Zollinger-Ellison,enfermedad de reflujo no erosivo (NERD), dolor visceral, quemadura solar, náusea, esfofaguitis, dosfagia, hipersalivación, trastornos de las vías aéreas o asma.
UY30043A 2005-12-19 2006-12-19 Derivados de bencimidazol sustituidos con cromano UY30043A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75218105P 2005-12-19 2005-12-19
US80294406P 2006-05-23 2006-05-23

Publications (1)

Publication Number Publication Date
UY30043A1 true UY30043A1 (es) 2007-07-31

Family

ID=37912450

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30043A UY30043A1 (es) 2005-12-19 2006-12-19 Derivados de bencimidazol sustituidos con cromano

Country Status (19)

Country Link
US (1) US7723321B2 (es)
EP (1) EP1963311B1 (es)
JP (1) JP4481344B2 (es)
KR (1) KR101088247B1 (es)
CN (2) CN101341149B (es)
AR (1) AR058120A1 (es)
AT (1) ATE471319T1 (es)
BR (2) BR122020004679B1 (es)
CA (1) CA2631880C (es)
DE (1) DE602006014996D1 (es)
DO (1) DOP2006000285A (es)
ES (1) ES2345726T3 (es)
GT (1) GT200600514A (es)
HK (1) HK1125368A1 (es)
NL (1) NL2000371C2 (es)
PE (1) PE20071182A1 (es)
TW (1) TW200732326A (es)
UY (1) UY30043A1 (es)
WO (1) WO2007072146A1 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2173721B1 (en) * 2007-06-26 2011-12-28 Sanofi A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
JP5802898B2 (ja) 2009-07-09 2015-11-04 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
KR101472686B1 (ko) 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법
KR102084185B1 (ko) 2013-08-29 2020-03-04 주식회사 대웅제약 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법
KR102129842B1 (ko) * 2013-10-02 2020-07-06 주식회사 대웅제약 술포닐인돌 유도체 및 이의 제조방법
RU2693484C1 (ru) 2013-11-22 2019-07-03 СиЭль БАЙОСАЕНСИЗ ЭлЭлСи Антагонисты гастрина для лечения и профилактики остеопороза
CN105440016B (zh) * 2014-08-11 2018-08-31 江苏柯菲平医药股份有限公司 吲哚、氮杂吲哚类衍生物、其制备方法及其在医药上的应用
KR101684053B1 (ko) * 2015-01-20 2016-12-08 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법
KR101613245B1 (ko) 2015-04-27 2016-04-18 주식회사 대웅제약 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
PL3305291T3 (pl) * 2015-06-08 2021-11-02 Hk Inno.N Corporation Zastosowania pochodnej benzimidazolu w nocnym przełomie wydzielania kwasu
KR101769204B1 (ko) * 2015-08-04 2017-08-17 씨제이헬스케어 주식회사 크로마놀 유도체의 신규한 제조방법
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR101829685B1 (ko) * 2016-07-28 2018-02-19 씨제이헬스케어 주식회사 안정성 및 용해도가 개선된 주사용 조성물
KR101829705B1 (ko) * 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 안정성이 향상된 주사용 조성물
KR101829706B1 (ko) * 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염
US11142591B2 (en) * 2016-12-20 2021-10-12 Exxonmobil Chemical Patents Inc. Polymerization process
KR101960357B1 (ko) 2016-12-26 2019-03-20 씨제이헬스케어 주식회사 벤즈이미다졸 유도체를 포함하는 신규한 제제
KR102233456B1 (ko) * 2017-05-31 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR102262743B1 (ko) * 2017-07-07 2021-06-09 에이치케이이노엔 주식회사 주사용 조성물
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
TWI676477B (zh) * 2017-12-05 2019-11-11 南韓商Ｃｊ醫藥健康股份有限公司 苯并咪唑衍生物用於夜間酸突破的用途
KR20200024413A (ko) * 2018-08-28 2020-03-09 에이치케이이노엔 주식회사 항혈소판제와 산 분비 억제제를 포함하는 약학 조성물
JOP20190201A1 (ar) * 2018-08-29 2020-02-29 Hk Inno N Corp تركيبة لاستئصال الملوية البوابية
CN109320485B (zh) * 2018-12-02 2021-06-18 江苏慧聚药业有限公司 合成特戈拉赞手性醇的方法
EA202192286A1 (ru) * 2019-02-18 2021-11-18 ЭйчКей ИННО.Эн КОРПОРЕЙШН Фармацевтическая композиция, содержащая соединение-производное бензимидазола
CN112851646B (zh) * 2019-11-12 2023-06-13 中国医学科学院药物研究所 特戈拉赞的制备方法
UY39094A (es) * 2020-02-27 2021-07-30 Hk Inno N Corp Composición farmacéutica que comprende compuesto derivado de bencimidazol
CN111303131B (zh) * 2020-03-19 2021-06-04 江苏慧聚药业有限公司 特戈拉赞(Tegoprazan)类似物及其合成方法
JP2023521197A (ja) 2020-04-13 2023-05-23 エイチケー イノ．エヌ コーポレーション ベンズイミダゾール誘導体化合物を含む医薬組成物
AR123872A1 (es) 2020-10-23 2023-01-18 Hk Inno N Corp Comprimido de desintegración oral, procedimiento de preparación del mismo, procedimiento para prevenir o tratar enfermedades y uso del mismo
CN112358450A (zh) * 2020-11-19 2021-02-12 南京艾康生物科技有限公司 一种4-(苄氧基)-2-甲基-1H-苯并[d]咪唑-6-羧酸的合成方法
KR20220141700A (ko) 2021-04-13 2022-10-20 에이치케이이노엔 주식회사 벤즈이미다졸 유도체 화합물을 포함하는 약학적 조성물
CN113527272B (zh) * 2021-08-06 2023-07-21 西安淳甄新材料有限公司 一种特戈拉赞的合成方法
WO2023106841A1 (ko) * 2021-12-08 2023-06-15 (주) 팜젠사이언스 벤즈이미다졸 유도체 화합물 및 이의 용도
KR20230099093A (ko) * 2021-12-27 2023-07-04 에이치케이이노엔 주식회사 벤즈이미다졸 유도체의 제조방법
CN114805317A (zh) * 2022-05-20 2022-07-29 江苏威奇达药业有限公司 一种特戈拉赞的制备方法
KR20240028127A (ko) 2022-08-24 2024-03-05 위더스제약주식회사 테고프라잔 고체분산체 조성물
WO2024045255A1 (zh) * 2022-08-30 2024-03-07 上海皓元医药股份有限公司 一种特戈拉赞晶型b及其制备方法
WO2024087155A1 (zh) * 2022-10-28 2024-05-02 深圳市华先医药科技有限公司 一种合成4-羟基-n,n,2-三甲基苯并咪唑-6-甲酰胺的方法
WO2024087156A1 (zh) * 2022-10-28 2024-05-02 深圳市华先医药科技有限公司 4-羟基-n,n,2-三甲基苯并咪唑-6-甲酰胺的可放大生产方法
KR102638900B1 (ko) 2023-01-27 2024-02-21 스마트바이오팜 주식회사 테고프라잔 중간체를 제조하는 방법 및 이에 사용되는 신규 중간체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
US5444775A (en) 1993-11-09 1995-08-22 Tobish; John J. Telephone key selection aid
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds
GB9914022D0 (en) 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
CA2608582A1 (en) * 2005-06-14 2006-12-21 Pfizer Inc. Chromane substituted benzimidazole derivatives as acid pump antagonists

Also Published As

Publication number Publication date
EP1963311B1 (en) 2010-06-16
CA2631880C (en) 2011-03-29
US7723321B2 (en) 2010-05-25
NL2000371C2 (nl) 2007-09-06
DE602006014996D1 (de) 2010-07-29
BRPI0620081B8 (pt) 2021-05-25
PE20071182A1 (es) 2008-02-07
BR122020004679B1 (pt) 2021-09-21
US20070142448A1 (en) 2007-06-21
KR101088247B1 (ko) 2011-11-30
KR20080080195A (ko) 2008-09-02
HK1125368A1 (en) 2009-08-07
GT200600514A (es) 2007-07-17
ES2345726T3 (es) 2010-09-30
EP1963311A1 (en) 2008-09-03
WO2007072146A1 (en) 2007-06-28
BRPI0620081A2 (pt) 2011-11-01
CN102321077A (zh) 2012-01-18
JP2009520017A (ja) 2009-05-21
ATE471319T1 (de) 2010-07-15
AR058120A1 (es) 2008-01-23
BRPI0620081B1 (pt) 2020-10-20
DOP2006000285A (es) 2007-07-31
JP4481344B2 (ja) 2010-06-16
TW200732326A (en) 2007-09-01
NL2000371A1 (nl) 2007-06-20
CN101341149A (zh) 2009-01-07
CA2631880A1 (en) 2007-06-28
CN101341149B (zh) 2011-06-08

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