DK70787A - Umaettede aminosyrer og salte deraf samt deres fremstilling og anvendelse - Google Patents

Umaettede aminosyrer og salte deraf samt deres fremstilling og anvendelse

Info

Publication number
DK70787A
DK70787A DK070787A DK70787A DK70787A DK 70787 A DK70787 A DK 70787A DK 070787 A DK070787 A DK 070787A DK 70787 A DK70787 A DK 70787A DK 70787 A DK70787 A DK 70787A
Authority
DK
Denmark
Prior art keywords
alkyl
amino
hydroxy
salts
phosphono
Prior art date
Application number
DK070787A
Other languages
English (en)
Other versions
DK70787D0 (da
DK169341B1 (da
Inventor
Christof Angst
Derek Edward Brundish
John Grey Dingwall
Graham Eric Fagg
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK70787D0 publication Critical patent/DK70787D0/da
Publication of DK70787A publication Critical patent/DK70787A/da
Application granted granted Critical
Publication of DK169341B1 publication Critical patent/DK169341B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826Acyclic unsaturated acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/302Acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3217Esters of acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015Esters of acyclic unsaturated acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK070787A 1986-02-13 1987-02-12 2-Amino-omega-phospono-alk-3-ensyreforbindelser og salte deraf, fremgangsmåde til deres fremstilling, farmaceutiske præparater med indhold deraf, deres anvendelse til fremstilling af farmaceutiske præparater samt forbindelserne til anvendelse ved en fremgangsmåde til terapeutisk behandling af humane eller animalske legemer DK169341B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH57886 1986-02-13
CH57886 1986-02-13

Publications (3)

Publication Number Publication Date
DK70787D0 DK70787D0 (da) 1987-02-12
DK70787A true DK70787A (da) 1987-08-14
DK169341B1 DK169341B1 (da) 1994-10-10

Family

ID=4190244

Family Applications (1)

Application Number Title Priority Date Filing Date
DK070787A DK169341B1 (da) 1986-02-13 1987-02-12 2-Amino-omega-phospono-alk-3-ensyreforbindelser og salte deraf, fremgangsmåde til deres fremstilling, farmaceutiske præparater med indhold deraf, deres anvendelse til fremstilling af farmaceutiske præparater samt forbindelserne til anvendelse ved en fremgangsmåde til terapeutisk behandling af humane eller animalske legemer

Country Status (23)

Country Link
EP (1) EP0233154B1 (da)
JP (2) JPH0717665B2 (da)
KR (1) KR900003533B1 (da)
AT (1) ATE70535T1 (da)
AU (1) AU610493B2 (da)
CA (1) CA1331625C (da)
CY (1) CY1821A (da)
DD (1) DD263775A5 (da)
DE (1) DE3775229D1 (da)
DK (1) DK169341B1 (da)
ES (1) ES2038690T3 (da)
FI (1) FI85144C (da)
GR (1) GR3003526T3 (da)
HK (1) HK95594A (da)
HU (1) HU204532B (da)
IE (1) IE59417B1 (da)
IL (1) IL81543A0 (da)
NO (1) NO170938C (da)
NZ (1) NZ219255A (da)
PH (1) PH23762A (da)
PT (1) PT84270B (da)
SG (1) SG92294G (da)
ZA (1) ZA871022B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175344A (en) * 1986-02-13 1992-12-29 Ciba-Geigy Corporation Unsaturated amino acids
EP0263502A3 (de) * 1986-10-09 1990-05-02 Ciba-Geigy Ag Oligopeptid-Antibiotika
EP0302826A3 (de) * 1987-08-04 1991-04-03 Ciba-Geigy Ag Verfahren zur Herstellung neuer ungesättigter Aminosäureverbindungen
US5175153A (en) * 1987-11-30 1992-12-29 Warner-Lambert Company Substituted alpha-amino acids having pharmaceutical activity
US5179085A (en) * 1989-03-15 1993-01-12 Warner-Lambert Company N-substituted α-amino acids and derivatives thereof having pharmaceutical activity
DE59007300D1 (de) * 1989-04-07 1994-11-03 Ciba Geigy Ag Ungesättigte Aminodicarbonsäurederivate.
US5500419A (en) * 1989-09-19 1996-03-19 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5294734A (en) * 1989-09-26 1994-03-15 Ciba-Geigy Corp. 4-substituted 2-aminoalk-3-enoic acids
DE59009368D1 (de) * 1989-09-26 1995-08-10 Ciba Geigy Ag Phosphonsäure, Verfahren zur Herstellung und Verwendung als Arzneimittelwirkstoff.
US5488140A (en) * 1989-09-26 1996-01-30 Ciba-Geigy Corporation 4-substituted 2-aminoalk-3-enoic
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
JPH07505908A (ja) * 1992-09-28 1995-06-29 マックセチーニ、マリア ルイザ Nmda受容体のアロステリックモジュレーター
CA2626435A1 (en) * 2005-10-18 2007-05-10 Centre National De La Recherche Scientifique (Cnrs) Hypophosphorous acid derivatives and their therapeutical applications
DE102007032669A1 (de) 2007-07-13 2009-01-15 Clariant International Limited Alkylphosphonigsäuren, -salze und -ester, Verfahren zu deren Herstellung und ihre Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2104079B (en) * 1981-08-14 1985-08-21 London Polytech New aminoacid isomers, their production and their medicinal use
US4477391A (en) * 1981-08-14 1984-10-16 Collins James F Amino acid isomers, their production and their medicinal use

Also Published As

Publication number Publication date
NO870577L (no) 1987-08-14
ES2038690T3 (es) 1993-08-01
PT84270A (en) 1987-03-01
NO870577D0 (no) 1987-02-13
PH23762A (en) 1989-11-03
GR3003526T3 (da) 1993-03-16
IE59417B1 (en) 1994-02-23
DK70787D0 (da) 1987-02-12
FI870558A7 (fi) 1987-08-14
SG92294G (en) 1995-04-28
DD263775A5 (de) 1989-01-11
CA1331625C (en) 1994-08-23
HK95594A (en) 1994-09-16
ATE70535T1 (de) 1992-01-15
ZA871022B (en) 1987-09-30
IE870365L (en) 1987-08-13
NO170938C (no) 1992-12-30
KR870007942A (ko) 1987-09-23
AU610493B2 (en) 1991-05-23
FI85144B (fi) 1991-11-29
EP0233154A3 (en) 1989-06-14
EP0233154B1 (de) 1991-12-18
NO170938B (no) 1992-09-21
NZ219255A (en) 1989-08-29
HUT43863A (en) 1987-12-28
DK169341B1 (da) 1994-10-10
IL81543A0 (en) 1987-09-16
PT84270B (pt) 1989-09-14
JPH07206683A (ja) 1995-08-08
JPS62246586A (ja) 1987-10-27
JP2509465B2 (ja) 1996-06-19
AU6872687A (en) 1987-08-20
HU204532B (en) 1992-01-28
JPH0717665B2 (ja) 1995-03-01
DE3775229D1 (de) 1992-01-30
FI85144C (fi) 1992-03-10
CY1821A (en) 1995-10-20
FI870558A0 (fi) 1987-02-11
KR900003533B1 (ko) 1990-05-21
EP0233154A2 (de) 1987-08-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PBP Patent lapsed