GB2104079B - New aminoacid isomers, their production and their medicinal use - Google Patents

New aminoacid isomers, their production and their medicinal use

Info

Publication number
GB2104079B
GB2104079B GB08223364A GB8223364A GB2104079B GB 2104079 B GB2104079 B GB 2104079B GB 08223364 A GB08223364 A GB 08223364A GB 8223364 A GB8223364 A GB 8223364A GB 2104079 B GB2104079 B GB 2104079B
Authority
GB
United Kingdom
Prior art keywords
isomers
production
medicinal use
new aminoacid
aminoacid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08223364A
Other versions
GB2104079A (en
Inventor
Kenneth Curry
Robert Schwarcz
James Friel Collins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LONDON POLYTECH
Original Assignee
LONDON POLYTECH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LONDON POLYTECH filed Critical LONDON POLYTECH
Priority to GB08223364A priority Critical patent/GB2104079B/en
Publication of GB2104079A publication Critical patent/GB2104079A/en
Application granted granted Critical
Publication of GB2104079B publication Critical patent/GB2104079B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3826—Acyclic unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015—Esters of acyclic unsaturated acids
GB08223364A 1981-08-14 1982-08-13 New aminoacid isomers, their production and their medicinal use Expired GB2104079B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08223364A GB2104079B (en) 1981-08-14 1982-08-13 New aminoacid isomers, their production and their medicinal use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8124900 1981-08-14
GB08223364A GB2104079B (en) 1981-08-14 1982-08-13 New aminoacid isomers, their production and their medicinal use

Publications (2)

Publication Number Publication Date
GB2104079A GB2104079A (en) 1983-03-02
GB2104079B true GB2104079B (en) 1985-08-21

Family

ID=26280468

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08223364A Expired GB2104079B (en) 1981-08-14 1982-08-13 New aminoacid isomers, their production and their medicinal use

Country Status (1)

Country Link
GB (1) GB2104079B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT40447A (en) * 1984-03-29 1986-12-28 Sandoz Ag Process for preparing substituted alpha-amino acids and pharmaceutical compositions containing such compounds
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
US4906621A (en) * 1985-05-24 1990-03-06 Ciba-Geigy Corporation Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade
US5217963A (en) * 1985-05-24 1993-06-08 Ciba-Geigy Corporation Certain phosphonic acid quinoline-2-carboxylic acids, esters or amides useful for treatment of disorders responsive to N-methyl D-aspartate receptor blockade
PH23848A (en) 1985-05-24 1989-11-23 Ciba Geigy Ag Certain phosphonic acids and derivatives
ES2038690T3 (en) * 1986-02-13 1993-08-01 Ciba-Geigy Ag UNSATURATED AMINO ACIDS.
EP0263502A3 (en) * 1986-10-09 1990-05-02 Ciba-Geigy Ag Oligopeptide antibiotics
ATE60776T1 (en) * 1986-11-21 1991-02-15 Ciba Geigy Ag UNSATURATED PHOSPHONIC ACIDS AND DERIVATIVES.
US5294734A (en) * 1989-09-26 1994-03-15 Ciba-Geigy Corp. 4-substituted 2-aminoalk-3-enoic acids
US5488140A (en) * 1989-09-26 1996-01-30 Ciba-Geigy Corporation 4-substituted 2-aminoalk-3-enoic
WO1992001455A1 (en) * 1990-07-25 1992-02-06 Luedke Hans Werner Medicament against degenerative brain performance diseases of the alzheimer type and cholinergic system disturbances
US5157149A (en) * 1991-06-04 1992-10-20 The United States Of America As Represented By The United States Department Of Energy Enantioselective synthesis of L-(-)-4- boronophenylalanine (L-BPA)
EP1929995A1 (en) 2006-12-04 2008-06-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Anaplerotic therapy of Huntington disease and other polyglutamine diseases
EP2931269B1 (en) 2012-12-13 2019-05-15 Baylor Research Institute at Dallas Triheptanoin for the treatment of glucose transporter 1 deficiency
AU2014348457B2 (en) 2013-11-14 2019-04-18 The University Of Queensland Neurodegenerative disorders and methods of treatment and diagnosis thereof
WO2018193999A1 (en) 2017-04-17 2018-10-25 国立大学法人京都大学 Optically-active 2-amino-phosphonoalkane acid, optically-active 2-amino-phosphonoalkane acid salt, and hydrates of these

Also Published As

Publication number Publication date
GB2104079A (en) 1983-03-02

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee