DK334581A - Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf - Google Patents

Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf

Info

Publication number
DK334581A
DK334581A DK334581A DK334581A DK334581A DK 334581 A DK334581 A DK 334581A DK 334581 A DK334581 A DK 334581A DK 334581 A DK334581 A DK 334581A DK 334581 A DK334581 A DK 334581A
Authority
DK
Denmark
Prior art keywords
hydroxyotahydro
benzo
amino
preparing
acid addition
Prior art date
Application number
DK334581A
Other languages
Danish (da)
English (en)
Inventor
M R Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK334581A publication Critical patent/DK334581A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines
DK334581A 1980-07-28 1981-07-27 Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf DK334581A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (1)

Publication Number Publication Date
DK334581A true DK334581A (da) 1982-01-29

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
DK334581A DK334581A (da) 1980-07-28 1981-07-27 Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf

Country Status (29)

Country Link
US (1) US4309545A (de)
EP (1) EP0045171B1 (de)
JP (1) JPS57112372A (de)
KR (1) KR850000273B1 (de)
AR (1) AR230988A1 (de)
AT (1) ATE11775T1 (de)
AU (1) AU525944B2 (de)
CA (1) CA1178274A (de)
CS (1) CS228515B2 (de)
DD (1) DD202012A5 (de)
DE (1) DE3168891D1 (de)
DK (1) DK334581A (de)
EG (1) EG15535A (de)
ES (1) ES504323A0 (de)
FI (1) FI812338L (de)
GR (1) GR75283B (de)
GT (1) GT198170557A (de)
HU (1) HU185133B (de)
IE (1) IE51426B1 (de)
IL (1) IL63423A0 (de)
IN (1) IN158867B (de)
NO (2) NO812557L (de)
NZ (1) NZ197856A (de)
PH (1) PH17281A (de)
PL (1) PL133928B1 (de)
PT (1) PT73440B (de)
SU (1) SU1217254A3 (de)
YU (1) YU185181A (de)
ZA (1) ZA815128B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
EE03523B1 (et) * 1996-01-31 2001-10-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
JP4141501B2 (ja) * 1996-03-26 2008-08-27 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の6位置換フェナントリジン
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
JP2001510827A (ja) * 1997-07-25 2001-08-07 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 置換6−フェニルフェナントリジン
DK1000034T3 (da) * 1997-07-25 2003-01-27 Altana Pharma Ag Substituerede 6-alkylphenanthridiner
JP2002539246A (ja) 1999-03-22 2002-11-19 イミュジェン ファーマシューティカルズ インコーポレイティッド 免疫疾患の治療
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
WO2002026224A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2003080043A1 (en) * 2002-03-18 2003-10-02 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
ZA200610032B (en) * 2004-05-25 2008-11-26 Othera Holding Inc Oculoselective drugs and prodrugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
DE3168891D1 (en) 1985-03-28
SU1217254A3 (ru) 1986-03-07
YU185181A (en) 1983-12-31
PT73440A (en) 1981-08-01
EP0045171A2 (de) 1982-02-03
ES8301926A1 (es) 1982-12-16
CA1178274A (en) 1984-11-20
IE811686L (en) 1982-01-28
DD202012A5 (de) 1983-08-24
NO854454L (no) 1985-01-29
PL232331A1 (en) 1983-09-26
AR230988A1 (es) 1984-08-31
NZ197856A (en) 1984-10-19
JPS57112372A (en) 1982-07-13
GR75283B (de) 1984-07-13
ATE11775T1 (de) 1985-02-15
EP0045171A3 (en) 1982-04-28
ES504323A0 (es) 1982-12-16
IL63423A0 (en) 1981-10-30
NO812557L (no) 1982-01-29
AU7343481A (en) 1982-05-06
EG15535A (en) 1986-09-30
EP0045171B1 (de) 1985-02-13
US4309545A (en) 1982-01-05
KR850000273B1 (ko) 1985-03-15
AU525944B2 (en) 1982-12-09
PH17281A (en) 1984-07-06
ZA815128B (en) 1982-07-28
PL133928B1 (en) 1985-07-31
FI812338L (fi) 1982-01-29
IE51426B1 (en) 1986-12-24
HU185133B (en) 1984-12-28
IN158867B (de) 1987-02-07
CS228515B2 (en) 1984-05-14
KR830006217A (ko) 1983-09-20
PT73440B (en) 1983-06-20
GT198170557A (es) 1983-01-12

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AHS Application shelved for other reasons than non-payment