EG15535A - Process for preparing 9-amino-1-hydroxyoctahydro-benzo(c)quinolines and derivatives thereof - Google Patents

Process for preparing 9-amino-1-hydroxyoctahydro-benzo(c)quinolines and derivatives thereof

Info

Publication number
EG15535A
EG15535A EG431/81A EG43181A EG15535A EG 15535 A EG15535 A EG 15535A EG 431/81 A EG431/81 A EG 431/81A EG 43181 A EG43181 A EG 43181A EG 15535 A EG15535 A EG 15535A
Authority
EG
Egypt
Prior art keywords
hydroxyoctahydro
quinolines
benzo
derivatives
amino
Prior art date
Application number
EG431/81A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG15535A publication Critical patent/EG15535A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
EG431/81A 1980-07-28 1981-07-27 Process for preparing 9-amino-1-hydroxyoctahydro-benzo(c)quinolines and derivatives thereof EG15535A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (1)

Publication Number Publication Date
EG15535A true EG15535A (en) 1986-09-30

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
EG431/81A EG15535A (en) 1980-07-28 1981-07-27 Process for preparing 9-amino-1-hydroxyoctahydro-benzo(c)quinolines and derivatives thereof

Country Status (29)

Country Link
US (1) US4309545A (xx)
EP (1) EP0045171B1 (xx)
JP (1) JPS57112372A (xx)
KR (1) KR850000273B1 (xx)
AR (1) AR230988A1 (xx)
AT (1) ATE11775T1 (xx)
AU (1) AU525944B2 (xx)
CA (1) CA1178274A (xx)
CS (1) CS228515B2 (xx)
DD (1) DD202012A5 (xx)
DE (1) DE3168891D1 (xx)
DK (1) DK334581A (xx)
EG (1) EG15535A (xx)
ES (1) ES504323A0 (xx)
FI (1) FI812338L (xx)
GR (1) GR75283B (xx)
GT (1) GT198170557A (xx)
HU (1) HU185133B (xx)
IE (1) IE51426B1 (xx)
IL (1) IL63423A0 (xx)
IN (1) IN158867B (xx)
NO (2) NO812557L (xx)
NZ (1) NZ197856A (xx)
PH (1) PH17281A (xx)
PL (1) PL133928B1 (xx)
PT (1) PT73440B (xx)
SU (1) SU1217254A3 (xx)
YU (1) YU185181A (xx)
ZA (1) ZA815128B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
SI0882021T1 (en) * 1996-01-31 2003-10-31 Altana Pharma Ag New phenanthridines
SI0889886T1 (en) * 1996-03-26 2003-02-28 Altana Pharma Ag Novel phenanthridines substituted in the 6 position
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
IL133825A (en) * 1997-07-25 2005-12-18 Altana Pharma Ag Substituted 6-phenylphenanthridines, medicaments containing same and use thereof in the production of medicaments
WO1999005112A1 (en) * 1997-07-25 1999-02-04 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituted 6-alkylphenanthridines
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US6274635B1 (en) 1999-03-22 2001-08-14 Immugen Pharmaceuticals Inc. Alkylated resorcinol derivatives for the treatment of immune diseases
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
WO2005115375A1 (en) * 2004-05-25 2005-12-08 Othera Pharmaceuticals, Inc. Oculoselective drugs and prodrugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180917B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás 5, 6, 6a, 7-tetrahidro-benzo [c] kinolin-9(8H)-on-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
IE51426B1 (en) 1986-12-24
CA1178274A (en) 1984-11-20
HU185133B (en) 1984-12-28
YU185181A (en) 1983-12-31
EP0045171A2 (en) 1982-02-03
IL63423A0 (en) 1981-10-30
PT73440A (en) 1981-08-01
PL133928B1 (en) 1985-07-31
PL232331A1 (en) 1983-09-26
IE811686L (en) 1982-01-28
NZ197856A (en) 1984-10-19
EP0045171B1 (en) 1985-02-13
ZA815128B (en) 1982-07-28
ATE11775T1 (de) 1985-02-15
IN158867B (xx) 1987-02-07
GR75283B (xx) 1984-07-13
NO812557L (no) 1982-01-29
FI812338L (fi) 1982-01-29
NO854454L (no) 1985-01-29
DD202012A5 (de) 1983-08-24
JPS57112372A (en) 1982-07-13
KR850000273B1 (ko) 1985-03-15
PT73440B (en) 1983-06-20
CS228515B2 (en) 1984-05-14
AR230988A1 (es) 1984-08-31
DK334581A (da) 1982-01-29
ES8301926A1 (es) 1982-12-16
GT198170557A (es) 1983-01-12
SU1217254A3 (ru) 1986-03-07
US4309545A (en) 1982-01-05
DE3168891D1 (en) 1985-03-28
ES504323A0 (es) 1982-12-16
PH17281A (en) 1984-07-06
KR830006217A (ko) 1983-09-20
AU7343481A (en) 1982-05-06
EP0045171A3 (en) 1982-04-28
AU525944B2 (en) 1982-12-09

Similar Documents

Publication Publication Date Title
ZA791516B (en) Novel carbostyril derivatives and process for preparation thereof
YU281081A (en) Process for preparing 1-sulfo-2-oxo-azetidine derivatives
PT73672B (en) Process for preparing n-arylbenzamide derivatives
PT73186B (en) Process for preparing pyrazolopyrydazine derivatives
DE3169223D1 (en) 4-(3-carboxy-2-oxopropyl)-azetidino-2-ones and process for their preparation
EG15535A (en) Process for preparing 9-amino-1-hydroxyoctahydro-benzo(c)quinolines and derivatives thereof
DE3160156D1 (en) Process for preparing vinylphosphonic-acid derivatives
DE3166987D1 (en) 3-aminoindazole derivatives and process for preparation thereof
DE3166969D1 (en) 6-quinazolinesulfonyl derivatives and process for preparation thereof
ZA817733B (en) Piperazinylbenzoheterocyclic compounds and process for preparing same
YU42592B (en) Process for preparing 3-amino-propoxyphenyl derivatives
PT73026A (en) Process for preparing carbapenams and carbapen-2-ems
PT74153A (en) Process for preparing oxadiazolopyrimidine derivatives
GB2071655B (en) N-amidazolyl derivatives of1-chroman and process for their preparation
DE3172032D1 (en) 7-oxoprostacyclin derivatives and process for the preparation thereof
DE3265553D1 (en) Novel secalonic acid derivatives and method for preparing thereof
YU159481A (en) Process for preparing dibenzindole derivatives
ZW17881A1 (en) Heteroprostaglandin derivatives and processes for preparing them
DE3071273D1 (en) Disoxidant and process for preparing same
DE3160397D1 (en) Phenoxyalkane derivative and processes for preparing same
DE3169906D1 (en) 17-beta-ethynylsteroids and process for preparing same
GB2082176B (en) Heteroprostaglandin derivatives and processes for preparing them
IL67581A (en) Aminopropylaminobleomycin derivatives and process for preparation thereof
ZA814947B (en) Heteroprostaglandin derivatives and processes for preparing them
SG65486G (en) Process for preparing 16-hydroxy-17-aminoprepnane derivatives