DE3168891D1 - 9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof - Google Patents
9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereofInfo
- Publication number
- DE3168891D1 DE3168891D1 DE8181303339T DE3168891T DE3168891D1 DE 3168891 D1 DE3168891 D1 DE 3168891D1 DE 8181303339 T DE8181303339 T DE 8181303339T DE 3168891 T DE3168891 T DE 3168891T DE 3168891 D1 DE3168891 D1 DE 3168891D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxyoctahydrobenzo
- quinolines
- derivatives
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/173,207 US4309545A (en) | 1980-07-28 | 1980-07-28 | Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3168891D1 true DE3168891D1 (en) | 1985-03-28 |
Family
ID=22630983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8181303339T Expired DE3168891D1 (en) | 1980-07-28 | 1981-07-21 | 9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof |
Country Status (29)
Country | Link |
---|---|
US (1) | US4309545A (de) |
EP (1) | EP0045171B1 (de) |
JP (1) | JPS57112372A (de) |
KR (1) | KR850000273B1 (de) |
AR (1) | AR230988A1 (de) |
AT (1) | ATE11775T1 (de) |
AU (1) | AU525944B2 (de) |
CA (1) | CA1178274A (de) |
CS (1) | CS228515B2 (de) |
DD (1) | DD202012A5 (de) |
DE (1) | DE3168891D1 (de) |
DK (1) | DK334581A (de) |
EG (1) | EG15535A (de) |
ES (1) | ES504323A0 (de) |
FI (1) | FI812338L (de) |
GR (1) | GR75283B (de) |
GT (1) | GT198170557A (de) |
HU (1) | HU185133B (de) |
IE (1) | IE51426B1 (de) |
IL (1) | IL63423A0 (de) |
IN (1) | IN158867B (de) |
NO (2) | NO812557L (de) |
NZ (1) | NZ197856A (de) |
PH (1) | PH17281A (de) |
PL (1) | PL133928B1 (de) |
PT (1) | PT73440B (de) |
SU (1) | SU1217254A3 (de) |
YU (1) | YU185181A (de) |
ZA (1) | ZA815128B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4920221A (en) * | 1982-03-16 | 1990-04-24 | Pfizer Inc. | Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines |
US4642373A (en) * | 1982-03-16 | 1987-02-10 | Pfizer Inc. | Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents |
US4473704A (en) * | 1982-03-16 | 1984-09-25 | Pfizer Inc. | Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents |
US5605906A (en) * | 1995-03-24 | 1997-02-25 | Merck Frosst Canada, Inc. | Cannabinoid receptor agonists |
UA48216C2 (uk) * | 1996-01-31 | 2002-08-15 | Бік Гулден Ломберг Кеміше Фабрік Гмбх | Фенантридини та лікарський засіб для лікування захворювань дихальних шляхів |
CA2250569C (en) * | 1996-03-26 | 2005-05-10 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel phenanthridines substituted in the 6 position |
US6127378A (en) * | 1996-03-26 | 2000-10-03 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phenanthridines substituted in the 6 position |
US5776482A (en) * | 1996-03-29 | 1998-07-07 | University Of Iowa Research Foundation | Tetrahydroquinoline analogues for use in glaucoma treatment |
PT1000035E (pt) * | 1997-07-25 | 2003-04-30 | Altana Pharma Ag | 6-fenilfenantridinas substituidas |
US6214839B1 (en) * | 1997-07-25 | 2001-04-10 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Substituted 6-alkylphenanthridines |
JP2002539246A (ja) | 1999-03-22 | 2002-11-19 | イミュジェン ファーマシューティカルズ インコーポレイティッド | 免疫疾患の治療 |
US6566560B2 (en) | 1999-03-22 | 2003-05-20 | Immugen Pharmaceuticals, Inc. | Resorcinolic compounds |
US20060084021A1 (en) * | 2004-09-10 | 2006-04-20 | Kubicek Chris A | Wick holder |
WO2002026224A2 (en) * | 2000-09-28 | 2002-04-04 | Immugen Pharmaceuticals, Inc. | Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation |
WO2002026728A2 (en) * | 2000-09-28 | 2002-04-04 | Immugen Pharmaceuticals, Inc. | Antiviral methods and compounds |
AU2003214226A1 (en) * | 2002-03-18 | 2003-10-08 | Immugen Pharmaceuticals, Inc. | Topical formulations of resorcinols and cannibinoids and methods of use |
CN1964711A (zh) * | 2004-05-25 | 2007-05-16 | 奥特拉药物公司 | 眼睛选择性药物及前体药物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3839441A (en) * | 1969-10-27 | 1974-10-01 | Hoffmann La Roche | Intermediates for partially hydrogenated phenanthridines |
US3878219A (en) * | 1973-07-13 | 1975-04-15 | Abbott Lab | 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines |
US3928598A (en) * | 1973-11-05 | 1975-12-23 | Lilly Co Eli | Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug |
US4087545A (en) * | 1976-02-17 | 1978-05-02 | Eli Lilly And Company | Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs |
ZA772899B (en) | 1976-05-17 | 1978-04-26 | Pfizer | 9-hydroxyhexahydrobenzol(c)quinolines and intermediates therefor |
SE7704749L (sv) * | 1976-05-17 | 1977-12-05 | Pfizer | Kinoliner och forfarande och mellanprodukter for framstellning derav |
US4152450A (en) * | 1978-02-17 | 1979-05-01 | Eli Lilly And Company | 9-Amino-dibenzopyrans |
-
1980
- 1980-07-28 US US06/173,207 patent/US4309545A/en not_active Expired - Lifetime
-
1981
- 1981-07-03 IN IN429/DEL/81A patent/IN158867B/en unknown
- 1981-07-21 GT GT198170557A patent/GT198170557A/es unknown
- 1981-07-21 EP EP81303339A patent/EP0045171B1/de not_active Expired
- 1981-07-21 DE DE8181303339T patent/DE3168891D1/de not_active Expired
- 1981-07-21 AT AT81303339T patent/ATE11775T1/de not_active IP Right Cessation
- 1981-07-22 HU HU812141A patent/HU185133B/hu not_active IP Right Cessation
- 1981-07-22 SU SU813317052A patent/SU1217254A3/ru active
- 1981-07-23 CS CS815647A patent/CS228515B2/cs unknown
- 1981-07-23 PL PL1981232331A patent/PL133928B1/pl unknown
- 1981-07-24 DD DD81232067A patent/DD202012A5/de unknown
- 1981-07-24 CA CA000382558A patent/CA1178274A/en not_active Expired
- 1981-07-24 AR AR286204A patent/AR230988A1/es active
- 1981-07-24 GR GR65624A patent/GR75283B/el unknown
- 1981-07-24 IE IE1686/81A patent/IE51426B1/en unknown
- 1981-07-27 DK DK334581A patent/DK334581A/da not_active Application Discontinuation
- 1981-07-27 PH PH25968A patent/PH17281A/en unknown
- 1981-07-27 KR KR1019810002717A patent/KR850000273B1/ko active
- 1981-07-27 EG EG431/81A patent/EG15535A/xx active
- 1981-07-27 IL IL63423A patent/IL63423A0/xx unknown
- 1981-07-27 FI FI812338A patent/FI812338L/fi not_active Application Discontinuation
- 1981-07-27 ES ES504323A patent/ES504323A0/es active Granted
- 1981-07-27 ZA ZA815128A patent/ZA815128B/xx unknown
- 1981-07-27 NZ NZ197856A patent/NZ197856A/en unknown
- 1981-07-27 JP JP56117571A patent/JPS57112372A/ja active Pending
- 1981-07-27 NO NO812557A patent/NO812557L/no unknown
- 1981-07-27 AU AU73434/81A patent/AU525944B2/en not_active Ceased
- 1981-07-27 YU YU01851/81A patent/YU185181A/xx unknown
- 1981-07-28 PT PT73440A patent/PT73440B/pt not_active IP Right Cessation
-
1985
- 1985-11-08 NO NO854454A patent/NO854454L/no unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8328 | Change in the person/name/address of the agent |
Free format text: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUENCHEN |
|
8339 | Ceased/non-payment of the annual fee |