DK3214170T3 - Pluripotent stamcelle, der kan isoleres fra kropsvæv - Google Patents

Pluripotent stamcelle, der kan isoleres fra kropsvæv Download PDF

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Publication number
DK3214170T3
DK3214170T3 DK17163323.3T DK17163323T DK3214170T3 DK 3214170 T3 DK3214170 T3 DK 3214170T3 DK 17163323 T DK17163323 T DK 17163323T DK 3214170 T3 DK3214170 T3 DK 3214170T3
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isolated
stem cell
pluripotent stem
body tissue
tissue
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DK17163323.3T
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English (en)
Inventor
Mari Dezawa
Yoshinori Fujiyoshi
Youichi Nabeshima
Shohei Wakao
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Yoshinori Fujiyoshi
Youichi Nabeshima
Shohei Wakao
Kitada Masaaki
Mari Dezawa
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43449509&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3214170(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yoshinori Fujiyoshi, Youichi Nabeshima, Shohei Wakao, Kitada Masaaki, Mari Dezawa filed Critical Yoshinori Fujiyoshi
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Publication of DK3214170T3 publication Critical patent/DK3214170T3/da

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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
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DK17163323.3T 2009-07-15 2010-07-15 Pluripotent stamcelle, der kan isoleres fra kropsvæv DK3214170T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21378809P 2009-07-15 2009-07-15
US29015909P 2009-12-24 2009-12-24
EP10799956.7A EP2455452B2 (en) 2009-07-15 2010-07-15 Pluripotent stem cell that can be isolated from body tissue

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DK3214170T3 true DK3214170T3 (da) 2020-10-12

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ID=43449509

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10799956.7T DK2455452T4 (da) 2009-07-15 2010-07-15 Pluripotent stamcelle, der kan isoleres fra kropsvæv
DK17163323.3T DK3214170T3 (da) 2009-07-15 2010-07-15 Pluripotent stamcelle, der kan isoleres fra kropsvæv

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Application Number Title Priority Date Filing Date
DK10799956.7T DK2455452T4 (da) 2009-07-15 2010-07-15 Pluripotent stamcelle, der kan isoleres fra kropsvæv

Country Status (16)

Country Link
US (1) US9550975B2 (OSRAM)
EP (3) EP3680323B1 (OSRAM)
JP (7) JP5185443B2 (OSRAM)
KR (4) KR20120069663A (OSRAM)
CN (2) CN107012117B (OSRAM)
AU (1) AU2010271722B8 (OSRAM)
CA (1) CA2768238C (OSRAM)
DK (2) DK2455452T4 (OSRAM)
ES (3) ES2647360T5 (OSRAM)
HR (1) HRP20250245T1 (OSRAM)
HU (3) HUE071170T2 (OSRAM)
NO (1) NO2455452T3 (OSRAM)
PL (3) PL2455452T5 (OSRAM)
PT (2) PT2455452T (OSRAM)
SG (1) SG177705A1 (OSRAM)
WO (1) WO2011007900A1 (OSRAM)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9399758B2 (en) 2009-07-15 2016-07-26 Mari Dezawa SSEA3(+) pluripotent stem cell that can be isolated from body tissue
JP2014132830A (ja) * 2011-03-30 2014-07-24 Clio Inc 生体の臍帯又は脂肪組織から単離できる多能性幹細胞
JP2014133703A (ja) * 2011-03-30 2014-07-24 Clio Inc 生体組織から単離できるssea−3陽性の多能性幹細胞を含む他家移植用細胞治療用組成物
US9550975B2 (en) 2009-07-15 2017-01-24 Mari Dezawa SSEA-3 pluripotent stem cell isolated from body tissue
JP2013502220A (ja) 2009-08-21 2013-01-24 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ ヒト体細胞からの誘導多能性幹細胞の生成効率を向上させる方法
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
SG10201914092XA (en) * 2011-06-06 2020-03-30 ReGenesys BVBA Expansion of stem cells in hollow fiber bioreactors
US9453840B2 (en) 2011-07-27 2016-09-27 Kyoto University Markers for dopaminergic neuron progenitor cells
KR101751355B1 (ko) * 2011-08-24 2017-07-04 (주)아모레퍼시픽 인간 피부 진피 유래 성체 줄기세포
US20140248698A1 (en) 2011-10-21 2014-09-04 Arkray, Inc. Method for culturing pluripotency-maintained singly dispersed cells by means of laminar flow
CN104284976A (zh) * 2012-03-06 2015-01-14 Sct&B公司 胎盘干细胞及其分离方法与应用
AU2013251649B2 (en) * 2012-04-24 2019-04-04 Vcell Therapeutics, Inc. Generating pluripotent cells de novo
US20140030244A1 (en) * 2012-07-27 2014-01-30 Bioquark, Inc. Extracts isolated from electroporated ambhibian oocytes and use thereof in treating diseases and disorders
WO2014027474A1 (ja) 2012-08-17 2014-02-20 株式会社Clio 心筋梗塞の修復再生を誘導する多能性幹細胞
TW201441369A (zh) * 2012-12-21 2014-11-01 Univ Rutgers 多向分化壓力耐受(muse)細胞分離及擴增
US9709554B2 (en) 2013-01-31 2017-07-18 Rutgers, The State University Of New Jersey In vitro model of macrosteatotic (fatty) liver
US20160002599A1 (en) 2013-02-08 2016-01-07 Kyoto University Production methods for megakaryocytes and platelets
JPWO2014133090A1 (ja) * 2013-02-28 2017-02-02 国立大学法人浜松医科大学 脳腫瘍治療のための多能性幹細胞
US9446033B2 (en) 2013-03-01 2016-09-20 Clio, Inc. Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to injury
AU2014239954B2 (en) * 2013-03-15 2020-07-16 The Jackson Laboratory Isolation of non-embryonic stem cells and uses thereof
US10519421B2 (en) 2013-03-21 2019-12-31 Kyoto University Induction of motor neurons from pluripotent stem cells
JP6473686B2 (ja) 2013-03-25 2019-02-20 公益財団法人神戸医療産業都市推進機構 細胞の選別方法
JP6461787B2 (ja) 2013-04-12 2019-01-30 国立大学法人京都大学 肺胞上皮前駆細胞の誘導方法
EP2998391B1 (en) 2013-05-14 2020-02-19 Kyoto University Efficient myocardial cell induction method
US10131880B2 (en) 2013-05-22 2018-11-20 The Regents Of The University Of California Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications
AU2014296259B2 (en) 2013-07-30 2017-04-27 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
EP3031905A4 (en) 2013-08-07 2017-04-26 Kyoto University Method for producing pancreatic hormone-producing cell
US10265347B2 (en) 2013-08-29 2019-04-23 Norimasa Miura Biomolecular group related to cell anti-aging
WO2015033558A1 (ja) 2013-09-04 2015-03-12 株式会社大塚製薬工場 多能性幹細胞の調製方法
CN121136933A (zh) 2013-09-05 2025-12-16 国立大学法人京都大学 由多能干细胞制造产多巴胺神经前体细胞的方法、产多巴胺神经前体细胞、帕金森病治疗剂和试剂盒
EP3064577B1 (en) 2013-11-01 2020-09-09 Kyoto University Novel chondrocyte induction method
WO2015081094A1 (en) * 2013-11-27 2015-06-04 University Of Louisville Research Foundation, Inc. Cardiac progenitor cells and methods of use therefor
JP6519038B2 (ja) * 2014-02-26 2019-05-29 株式会社生命科学インスティテュート 脳梗塞治療のための多能性幹細胞
JP2015160820A (ja) * 2014-02-26 2015-09-07 株式会社Clio 慢性腎障害治療のための多能性幹細胞
RU2711942C2 (ru) 2014-03-19 2020-01-23 Виселл Терапеутикс, Инк. Способы, относящиеся к плюрипотентным клеткам
WO2015178431A1 (ja) 2014-05-21 2015-11-26 国立大学法人京都大学 膵芽細胞の製造方法および膵芽細胞を含む膵疾患治療剤
KR101592401B1 (ko) * 2014-06-13 2016-02-05 주식회사 비비에이치씨 지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법 및 그 방법에 의해 제조된 유도만능 줄기세포
JP6391364B2 (ja) * 2014-08-25 2018-09-19 国立大学法人 鹿児島大学 認知機能障害改善用細胞製剤
JP6452107B2 (ja) * 2014-09-05 2019-01-16 国立大学法人 東京大学 糖尿病性皮膚潰瘍治療のための多能性幹細胞
KR101700598B1 (ko) * 2014-11-11 2017-01-31 한국원자력의학원 Cd105를 포함하는 줄기세포능을 가진 섬유아세포 분리용 바이오마커 조성물 및 이를 이용한 줄기세포능을 가진 섬유아세포 분리 방법
WO2016187413A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
JP6169807B2 (ja) * 2015-05-29 2017-07-26 日本臓器製薬株式会社 多能性幹細胞遊走促進剤
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
JP6627027B2 (ja) * 2015-09-11 2020-01-08 福美人株式会社 皮膚細胞の活性化作用を呈するフラボノイド誘導体
KR20200101991A (ko) * 2016-01-15 2020-08-28 국립대학법인 도야마 다이가쿠 허혈성 뇌경색에의 다능성 줄기 세포의 동원
JP6770673B2 (ja) * 2016-02-26 2020-10-21 国立大学法人東海国立大学機構 急性心筋梗塞の予後マーカー及びその利用
DK3430122T3 (da) * 2016-03-17 2021-08-23 Synova Life Sciences Inc Separering, adskillelse og/eller opdeling af celler ved hjælp af mekaniske stød
CN109072198B (zh) 2016-04-22 2022-08-26 国立大学法人京都大学 产多巴胺神经祖细胞的制备方法
JP6994200B2 (ja) * 2016-05-16 2022-02-04 国立大学法人東海国立大学機構 多能性幹細胞による周産期脳障害の改善及び治療
US20190201455A1 (en) 2016-07-01 2019-07-04 Tohoku University Prophylactic or therapeutic agent for organ fibrosis
CA3032358A1 (en) 2016-07-29 2018-02-01 Tohoku University Prophylactic or therapeutic agent for vascular disorder
AU2017305064B2 (en) 2016-08-03 2023-03-16 Life Science Institute, Inc. Amelioration and treatment of chronic lung disease using pluripotent stem cells
CN109689074A (zh) 2016-08-03 2019-04-26 株式会社生命科学研究院 采用多能干细胞的缺血再灌注肺损伤的减轻及治疗
WO2018025975A1 (ja) * 2016-08-03 2018-02-08 株式会社生命科学インスティテュート インビトロで多能性幹細胞を分化誘導する方法
WO2018143378A1 (ja) 2017-02-03 2018-08-09 国立大学法人九州大学 歯髄組織由来細胞から歯髄幹細胞を調製する方法
JP7181534B2 (ja) * 2017-03-28 2022-12-01 味の素株式会社 未分化維持培地添加剤
JP7712643B2 (ja) * 2017-06-19 2025-07-24 国立大学法人東北大学 表皮水疱症の治療剤
AU2018289947A1 (en) 2017-06-20 2020-01-30 Life Science Institute, Inc. Amelioration and treatment of brain disorder resulting from fetal growth retardation using pluripotent stem cells
JP7489016B2 (ja) * 2017-10-17 2024-05-23 国立大学法人東北大学 骨軟骨修復を誘導する多能性幹細胞
AU2018364852B2 (en) * 2017-11-10 2022-06-30 Regenesis Science Co., Ltd. Method for producing cultured cell, and method for producing therapeutic agent for spinal cord injury disease
CN111492248B (zh) 2017-11-28 2023-09-12 塞尔吐温株式会社 通过实时谷胱甘肽测定来测量治疗细胞质量的方法
JP6604492B2 (ja) * 2018-04-09 2019-11-13 株式会社生命科学インスティテュート 脳梗塞治療のための多能性幹細胞
EP3791888A4 (en) 2018-05-09 2022-03-23 Life Science Institute, Inc. Therapeutic agent for spinal cord injury
JP7072777B2 (ja) * 2018-07-03 2022-05-23 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
JP7285015B2 (ja) 2018-07-19 2023-06-01 国立大学法人京都大学 多能性幹細胞由来の板状軟骨およびその製造方法
WO2020100788A1 (ja) * 2018-11-14 2020-05-22 株式会社片岡製作所 インスリン産生細胞の製造方法、及び組成物
SG11202105686UA (en) * 2018-11-30 2021-06-29 Kyoto Prefectural Public Univ Corp Therapeutic agent of peripheral blood flow disorder
US12435311B2 (en) 2018-12-21 2025-10-07 The University Of Osaka Lubricin-localized cartilage-like tissue, method for producing same and composition comprising same for treating articular cartilage damage
JP2022528965A (ja) * 2019-04-09 2022-06-16 ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー 細胞集団を濃縮する方法
CA3150769A1 (en) 2019-08-09 2021-02-18 Tohoku University Agent for treating or preventing vascular dementia
EP4026551A1 (en) 2019-09-05 2022-07-13 Tohoku University Therapeutic agent for myocarditis
WO2021066076A1 (ja) 2019-10-01 2021-04-08 国立大学法人京都大学 尿管芽先端部細胞の単離方法
JPWO2021085639A1 (OSRAM) * 2019-10-31 2021-05-06
JP7058431B2 (ja) 2019-12-12 2022-04-22 国立大学法人千葉大学 巨核球および血小板を含む凍結乾燥製剤
WO2021187602A1 (ja) 2020-03-19 2021-09-23 国立大学法人京都大学 心筋細胞の精製方法
CA3175573A1 (en) 2020-03-19 2021-09-23 Orizuru Therapeutics, Inc. Cardiomyocyte purification method
CN115843311A (zh) 2020-04-02 2023-03-24 国立大学法人东北大学 高潜能多能干细胞
US20230256024A1 (en) 2020-07-13 2023-08-17 Kyoto University Skeletal muscle precursor cells and method for purifying same, composition for treating myogenic diseases, and method for producing cell group containing skeletal muscle precursor cells
US20230270790A1 (en) * 2020-07-15 2023-08-31 National University Corporation Okayama University Pluripotent stem cells effective for treatment of motor neuron disease (mnd)
JP2021073305A (ja) * 2021-02-09 2021-05-13 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
TWI832070B (zh) * 2021-07-15 2024-02-11 國璽幹細胞應用技術股份有限公司 幹細胞製劑用於治療關節炎的用途及用於製備幹細胞製劑的方法
JP2023041486A (ja) * 2021-09-13 2023-03-24 国立大学法人東北大学 毛髪損傷の治療剤
JPWO2023153464A1 (OSRAM) 2022-02-09 2023-08-17
EP4530344A1 (en) 2022-05-23 2025-04-02 Kyoto University Production method for renal collecting duct cells and pelvic epithelial cells
JPWO2024210126A1 (OSRAM) 2023-04-03 2024-10-10
WO2024248017A1 (ja) 2023-05-29 2024-12-05 国立研究開発法人理化学研究所 心筋細胞を成熟させる方法及び成熟した心筋細胞の製造方法
CN117187174B (zh) * 2023-11-08 2024-02-06 广州正源生物技术有限公司 一种Muse细胞培养基以及一种脂肪Muse细胞的提取方法
JP2025123077A (ja) * 2024-02-09 2025-08-22 国立大学法人東北大学 脊髄梗塞治療のための多能性幹細胞

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1049350B (en) 1999-08-05 2012-01-27 Abt Holding Company Multipotent adult stem cells and methods for isolation
US7575921B2 (en) * 1999-12-30 2009-08-18 Vbi Technologies, L.L.C. Spore-like cells and uses thereof
WO2002057428A1 (en) * 2000-10-30 2002-07-25 University Of Massachusetts Isolation of spore-like cells from tissues exposed to extreme conditions
JP4182742B2 (ja) 2002-12-12 2008-11-19 日産自動車株式会社 自動車の前部車体構造
US20050042595A1 (en) 2003-08-14 2005-02-24 Martin Haas Banking of multipotent amniotic fetal stem cells
CN1845987A (zh) * 2003-08-29 2006-10-11 明尼苏达大学董事会 肾来源的干细胞及其分离、分化和使用方法
US20060216821A1 (en) * 2004-02-26 2006-09-28 Reliance Life Sciences Pvt. Ltd. Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
JP2009517001A (ja) * 2005-05-17 2009-04-30 リライアンス ライフ サイエンシーズ プライベイト リミテッド 哺乳動物細胞を使用するヒト胚性幹細胞株の構築
US9388382B2 (en) * 2005-10-05 2016-07-12 The Board Of Trustees Of The University Of Illinois Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
AU2006304390A1 (en) 2005-10-17 2007-04-26 Academia Sinica Pulmonary stem cells, related methods and kits
WO2009059032A2 (en) * 2007-10-30 2009-05-07 University Of Louisville Research Foundation, Inc. Uses and isolation of very small embryonic-like (vsel) stem cells
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
WO2008080200A1 (en) 2006-12-29 2008-07-10 Irina Kerkis Process for obtaining stem cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US20090172832A1 (en) * 2007-12-28 2009-07-02 Timothy Caspar Expression of rubisco enzyme from a non-rubisco locus
ITRM20080342A1 (it) * 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
US9550975B2 (en) 2009-07-15 2017-01-24 Mari Dezawa SSEA-3 pluripotent stem cell isolated from body tissue

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