DK3213056T3 - Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund - Google Patents
Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund Download PDFInfo
- Publication number
- DK3213056T3 DK3213056T3 DK15855907.0T DK15855907T DK3213056T3 DK 3213056 T3 DK3213056 T3 DK 3213056T3 DK 15855907 T DK15855907 T DK 15855907T DK 3213056 T3 DK3213056 T3 DK 3213056T3
- Authority
- DK
- Denmark
- Prior art keywords
- glycosyled
- biomolecules
- procedures
- analysis
- same background
- Prior art date
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/98—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072747P | 2014-10-30 | 2014-10-30 | |
| US201562107994P | 2015-01-26 | 2015-01-26 | |
| PCT/US2015/057848 WO2016069764A1 (en) | 2014-10-30 | 2015-10-28 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3213056T3 true DK3213056T3 (da) | 2020-09-28 |
Family
ID=55858312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20188814.6T DK3748340T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme |
| DK15855907.0T DK3213056T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20188814.6T DK3748340T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11371996B2 (da) |
| EP (3) | EP3213056B1 (da) |
| JP (3) | JP7055634B2 (da) |
| CN (2) | CN107110785A (da) |
| DK (2) | DK3748340T3 (da) |
| WO (1) | WO2016069764A1 (da) |
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|---|---|---|---|---|
| US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| US10416166B2 (en) | 2011-09-28 | 2019-09-17 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| CN107110785A (zh) | 2014-10-30 | 2017-08-29 | 沃特世科技公司 | 快速制备标记的葡糖基胺和分析生产所述标记的葡糖基胺的糖基化生物分子的方法 |
| EP3744708B1 (en) | 2014-11-13 | 2023-08-09 | Waters Technologies Corporation | Calibrant for liquid chromatography calibration of labeled n-glycans |
| WO2017222954A1 (en) | 2016-06-21 | 2017-12-28 | Waters Technologies Corporation | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced ms signals |
| EP3471728A4 (en) * | 2016-06-21 | 2020-02-26 | Waters Technologies Corporation | METHOD FOR IMPROVING MS DETECTION OF LABELED GLYCANS |
| EP4234062A3 (en) * | 2016-06-21 | 2023-10-25 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
| CN114839302A (zh) | 2016-07-01 | 2022-08-02 | 沃特世科技公司 | 使用分子量截留过滤和过滤器上去糖基化从复杂基质快速制备标记的葡基胺的方法 |
| US11280766B2 (en) | 2016-07-28 | 2022-03-22 | Waters Technologies Corporation | Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis |
| WO2018067398A1 (en) * | 2016-10-03 | 2018-04-12 | Waters Technologies Corporation | Labeled glycan amino acid complexes useful in lc-ms analysis and methods of making the same |
| EP3601336A1 (en) * | 2017-03-31 | 2020-02-05 | Alexion Pharmaceuticals, Inc. | Method for simultaneous quantification of alxn1210 and eculizumab in human serum or urine |
| CN109254101B (zh) * | 2017-07-13 | 2021-07-09 | 中国科学院大连化学物理研究所 | 一种母乳酸性寡糖净化和分析方法 |
| US11231401B2 (en) | 2018-03-16 | 2022-01-25 | Quest Diagnostics Investments Llc | Methods for detecting chromogranin a by mass spectrometry |
| EP3821238B1 (en) | 2018-07-11 | 2022-08-31 | Waters Technologies Corporation | Chromatographic system and method for trap-elute mixed mode chromatography |
| IL294765B2 (en) * | 2020-01-21 | 2023-12-01 | Regeneron Pharma | Deglycosylation methods for electrophoresis of glycosylated proteins |
| CN113295778A (zh) * | 2021-04-02 | 2021-08-24 | 东莞太力生物工程有限公司 | 糖蛋白n-糖链分析方法 |
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2015
- 2015-10-28 CN CN201580071764.2A patent/CN107110785A/zh active Pending
- 2015-10-28 DK DK20188814.6T patent/DK3748340T3/da active
- 2015-10-28 JP JP2017523362A patent/JP7055634B2/ja active Active
- 2015-10-28 US US15/522,908 patent/US11371996B2/en active Active
- 2015-10-28 CN CN202211161685.9A patent/CN115753702A/zh active Pending
- 2015-10-28 EP EP15855907.0A patent/EP3213056B1/en active Active
- 2015-10-28 WO PCT/US2015/057848 patent/WO2016069764A1/en active Application Filing
- 2015-10-28 EP EP20188814.6A patent/EP3748340B1/en active Active
- 2015-10-28 EP EP22160505.8A patent/EP4033223A1/en active Pending
- 2015-10-28 DK DK15855907.0T patent/DK3213056T3/da active
-
2021
- 2021-03-31 JP JP2021059591A patent/JP2021119345A/ja active Pending
-
2022
- 2022-05-11 US US17/741,865 patent/US20220268779A1/en active Pending
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2023
- 2023-08-03 JP JP2023126905A patent/JP2023162207A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN107110785A (zh) | 2017-08-29 |
| JP2018501465A (ja) | 2018-01-18 |
| US20180188259A1 (en) | 2018-07-05 |
| EP3213056A4 (en) | 2018-08-08 |
| JP2023162207A (ja) | 2023-11-08 |
| EP3748340B1 (en) | 2022-04-06 |
| US20220268779A1 (en) | 2022-08-25 |
| JP2021119345A (ja) | 2021-08-12 |
| DK3748340T3 (da) | 2022-04-19 |
| EP4033223A1 (en) | 2022-07-27 |
| US11371996B2 (en) | 2022-06-28 |
| WO2016069764A1 (en) | 2016-05-06 |
| EP3213056A1 (en) | 2017-09-06 |
| EP3748340A1 (en) | 2020-12-09 |
| CN115753702A (zh) | 2023-03-07 |
| JP7055634B2 (ja) | 2022-04-18 |
| EP3213056B1 (en) | 2020-08-12 |
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