FR2788518B1 - Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees - Google Patents

Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees

Info

Publication number
FR2788518B1
FR2788518B1 FR9900330A FR9900330A FR2788518B1 FR 2788518 B1 FR2788518 B1 FR 2788518B1 FR 9900330 A FR9900330 A FR 9900330A FR 9900330 A FR9900330 A FR 9900330A FR 2788518 B1 FR2788518 B1 FR 2788518B1
Authority
FR
France
Prior art keywords
preparation
urea
stable active
novel stable
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9900330A
Other languages
English (en)
Other versions
FR2788518A1 (fr
Inventor
Gilles Guichard
Marc Rodruguez
Vincent Semetey
Jean Paul Briand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9900330A priority Critical patent/FR2788518B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to CA2360275A priority patent/CA2360275C/fr
Priority to EP00900588A priority patent/EP1140822A1/fr
Priority to JP2000593577A priority patent/JP2002534501A/ja
Priority to PCT/FR2000/000080 priority patent/WO2000042009A1/fr
Priority to AU30549/00A priority patent/AU3054900A/en
Publication of FR2788518A1 publication Critical patent/FR2788518A1/fr
Application granted granted Critical
Publication of FR2788518B1 publication Critical patent/FR2788518B1/fr
Priority to US09/904,459 priority patent/US7060845B2/en
Priority to US11/076,861 priority patent/US20050159585A1/en
Priority to US11/077,257 priority patent/US7186739B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G71/00—Macromolecular compounds obtained by reactions forming a ureide or urethane link, otherwise, than from isocyanate radicals in the main chain of the macromolecule
    • C08G71/02—Polyureas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
FR9900330A 1999-01-14 1999-01-14 Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees Expired - Fee Related FR2788518B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9900330A FR2788518B1 (fr) 1999-01-14 1999-01-14 Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees
EP00900588A EP1140822A1 (fr) 1999-01-14 2000-01-14 Nouveaux derives actives stables d'acide carbamique, leur procede de preparation et leur utilisation pour la preparation d'urees
JP2000593577A JP2002534501A (ja) 1999-01-14 2000-01-14 カルバミン酸の安定な新規活性化誘導体、その調製方法及び尿素調製のためのその利用
PCT/FR2000/000080 WO2000042009A1 (fr) 1999-01-14 2000-01-14 Nouveaux derives actives stables d'acide carbamique, leur procede de preparation et leur utilisation pour la preparation d'urees
CA2360275A CA2360275C (fr) 1999-01-14 2000-01-14 Stable activated novel carbamic acid derivatives, preparation method and use for preparing urea
AU30549/00A AU3054900A (en) 1999-01-14 2000-01-14 Stable activated novel carbamic acid derivatives, preparation method and use forpreparing urea
US09/904,459 US7060845B2 (en) 1999-01-14 2001-07-16 Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas
US11/076,861 US20050159585A1 (en) 1999-01-14 2005-03-11 Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas
US11/077,257 US7186739B2 (en) 1999-01-14 2005-03-11 Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9900330A FR2788518B1 (fr) 1999-01-14 1999-01-14 Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees

Publications (2)

Publication Number Publication Date
FR2788518A1 FR2788518A1 (fr) 2000-07-21
FR2788518B1 true FR2788518B1 (fr) 2001-03-02

Family

ID=9540844

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9900330A Expired - Fee Related FR2788518B1 (fr) 1999-01-14 1999-01-14 Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees

Country Status (7)

Country Link
US (3) US7060845B2 (fr)
EP (1) EP1140822A1 (fr)
JP (1) JP2002534501A (fr)
AU (1) AU3054900A (fr)
CA (1) CA2360275C (fr)
FR (1) FR2788518B1 (fr)
WO (1) WO2000042009A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830252B1 (fr) 2001-10-02 2005-02-04 Centre Nat Rech Scient Nouveaux oligomeres d'urees, leur procede de preparation et compositions pharmaceutiques les contenant
WO2006131833A2 (fr) * 2005-03-18 2006-12-14 Centre National De La Recherche Scientifique Nouveaux oligomeres hybrides, leur processus de preparation et compositions pharmaceutiques les contenant
US20080033167A1 (en) * 2005-12-29 2008-02-07 Gilles Guichard Compositions and methods for synthesizing heterocyclic therapeutic compounds
CA2667714C (fr) * 2006-10-27 2014-09-09 Metkinen Chemistry Oy Carbamoylation d'amines, de thiophenols, de mercaptans et de phenols mettant en oeuvre des azides organiques
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
WO2015024955A1 (fr) 2013-08-21 2015-02-26 Ureka Sarl Composés chimériques de peptide-oligourée et leurs procédés d'utilisation
DK3213056T3 (da) 2014-10-30 2020-09-28 Waters Technologies Corp Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund
CN111796039B (zh) 2014-11-13 2023-03-17 沃特世科技公司 快速标记的n-聚糖的液相色谱校准方法
US10414722B2 (en) 2015-06-22 2019-09-17 Ureka Sarl Bioinspired catalysis using oligourea helical foldamers
US10233213B2 (en) 2015-08-31 2019-03-19 Ureka Sarl Foldamer helix bundle-based molecular encapsulation
AU2017252015A1 (en) 2016-04-19 2018-11-08 Ureka Sarl Peptide-oligourea foldamer compounds and methods of their use
CN109641846A (zh) 2016-06-21 2019-04-16 沃特世科技公司 通过用于增强的ms信号的还原胺化的聚糖和其他生物分子的荧光标记
CN109642906A (zh) 2016-06-21 2019-04-16 沃特世科技公司 对用两亲强碱性部分改性的聚糖进行电喷雾电离的方法
CN109690297A (zh) 2016-07-01 2019-04-26 沃特世科技公司 使用分子量截留过滤和过滤器上去糖基化从复杂基质快速制备标记的葡基胺的方法
TWI756496B (zh) * 2017-11-27 2022-03-01 台灣積體電路製造股份有限公司 加熱台以及具有加熱台的設備
EP3911960A1 (fr) 2019-01-18 2021-11-24 UREKA Sarl Composés hybrides de peptide-oligourée

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1568629C3 (de) 1966-11-30 1974-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von organischen Isocyanaten
US4003912A (en) * 1973-06-11 1977-01-18 Monsanto Company Dicarboximido-N-phenylsubstituted carbamates and derivatives
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives
DE3435070A1 (de) * 1984-09-25 1986-04-03 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von gegebenenfalls geschaeumten polyurethanen, die mit einem anderen werkstoff verbunden oder konfektioniert worden sind
EP0209855A2 (fr) * 1985-07-18 1987-01-28 Board of Trustees of Wichita State University Dérivés des amino-acides utilisables pour la désactivation des enzymes
US4680338A (en) * 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
JPS62195361A (ja) * 1986-02-21 1987-08-28 Haruo Ogura 新規なアミノ基標識試薬化合物
US5296599A (en) * 1991-09-19 1994-03-22 Millipore Corporation Activated carbamates compounds
JP3583489B2 (ja) * 1994-12-22 2004-11-04 日清紡績株式会社 カルボジイミド誘導体
NZ313713A (en) * 1995-08-02 2001-03-30 Univ Newcastle Ventures Ltd Benzimidazole-4-carboxamide derivatives useful as poly(ADP-ribose)polymerase or PARP enzyme inhibitors

Also Published As

Publication number Publication date
WO2000042009A1 (fr) 2000-07-20
JP2002534501A (ja) 2002-10-15
EP1140822A1 (fr) 2001-10-10
US20020143191A1 (en) 2002-10-03
AU3054900A (en) 2000-08-01
FR2788518A1 (fr) 2000-07-21
US20050159585A1 (en) 2005-07-21
CA2360275C (fr) 2011-10-18
US7186739B2 (en) 2007-03-06
US20050159584A1 (en) 2005-07-21
CA2360275A1 (fr) 2000-07-20
US7060845B2 (en) 2006-06-13

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TQ Partial transmission of property
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FC Decision of inpi director general to approve request for restoration

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