DK2718431T3 - dsRNA endoribonucleases. - Google Patents

dsRNA endoribonucleases. Download PDF

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Publication number
DK2718431T3
DK2718431T3 DK12735349.8T DK12735349T DK2718431T3 DK 2718431 T3 DK2718431 T3 DK 2718431T3 DK 12735349 T DK12735349 T DK 12735349T DK 2718431 T3 DK2718431 T3 DK 2718431T3
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DK
Denmark
Prior art keywords
dsrna
endoribonuclease
sequence
seq
cleavage
Prior art date
Application number
DK12735349.8T
Other languages
Danish (da)
English (en)
Inventor
Janusz Marek Bujnicki
Krzysztof Jerzy Skowronek
Dariusz Pianka
Agata Agnieszka Sulej
Original Assignee
Miedzynarodowy Inst Biolog Molekularnej I Komorkowej
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Miedzynarodowy Inst Biolog Molekularnej I Komorkowej filed Critical Miedzynarodowy Inst Biolog Molekularnej I Komorkowej
Application granted granted Critical
Publication of DK2718431T3 publication Critical patent/DK2718431T3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003—Ribonuclease III (3.1.26.3)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK12735349.8T 2011-06-08 2012-06-07 dsRNA endoribonucleases. DK2718431T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161494574P 2011-06-08 2011-06-08
PL395178A PL222511B1 (pl) 2011-06-08 2011-06-08 Endorybonukleazy dsRNA
PCT/PL2012/050020 WO2012169917A1 (en) 2011-06-08 2012-06-07 Dsrna endoribonucleases

Publications (1)

Publication Number Publication Date
DK2718431T3 true DK2718431T3 (en) 2015-11-16

Family

ID=47296271

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12735349.8T DK2718431T3 (en) 2011-06-08 2012-06-07 dsRNA endoribonucleases.

Country Status (11)

Country Link
US (1) US9238805B2 (https=)
EP (1) EP2718431B1 (https=)
JP (1) JP6075892B2 (https=)
KR (1) KR20140045371A (https=)
CN (1) CN103764821B (https=)
AU (1) AU2012267271B2 (https=)
CA (1) CA2837143C (https=)
DK (1) DK2718431T3 (https=)
ES (1) ES2555661T3 (https=)
PL (1) PL222511B1 (https=)
WO (1) WO2012169917A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013055995A2 (en) 2011-10-14 2013-04-18 President And Fellows Of Harvard College Sequencing by structure assembly
EP4697020A2 (en) 2011-12-22 2026-02-18 President And Fellows Of Harvard College Compositions and methods for analyte detection
ES2991004T3 (es) 2011-12-22 2024-12-02 Harvard College Métodos para la detección de analitos
US9914967B2 (en) 2012-06-05 2018-03-13 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using DNA origami probes
EP3578666A1 (en) 2013-03-12 2019-12-11 President and Fellows of Harvard College Method of generating a three-dimensional nucleic acid containing matrix
EP4596565A3 (en) 2013-06-04 2025-11-05 President And Fellows Of Harvard College Rna-guided transcriptional regulation
WO2016007839A1 (en) 2014-07-11 2016-01-14 President And Fellows Of Harvard College Methods for high-throughput labelling and detection of biological features in situ using microscopy
CN104306989A (zh) * 2014-09-27 2015-01-28 郭和友 一种利用切割酶治疗细菌方法
JP6882282B2 (ja) 2015-11-03 2021-06-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 三次元核酸含有マトリックスの立体撮像のための方法と装置
PL415883A1 (pl) * 2016-01-22 2017-07-31 Międzynarodowy Instytut Biologii Molekularnej I Komórkowej RNazy MiniIII, sposoby zmiany specyficzności cięcia sekwencji RNA przez RNazy MiniIII oraz ich zastosowania
CN109415761B (zh) 2016-04-25 2022-09-20 哈佛学院董事及会员团体 用于原位分子检测的杂交链反应方法
CN109923216B (zh) 2016-08-31 2024-08-02 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
GB2570412A (en) 2016-08-31 2019-07-24 Harvard College Methods of generating libraries of nucleic acid sequences for detection via fluorescent in situ sequencing
WO2018134386A1 (en) * 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
CN112770776B (zh) 2018-07-30 2025-08-19 瑞德库尔有限责任公司 用于样品处理或分析的方法和系统
WO2020076976A1 (en) 2018-10-10 2020-04-16 Readcoor, Inc. Three-dimensional spatial molecular indexing
WO2021155063A1 (en) 2020-01-29 2021-08-05 Readcoor, Llc Compositions and methods for analyte detection
US20220049303A1 (en) 2020-08-17 2022-02-17 Readcoor, Llc Methods and systems for spatial mapping of genetic variants
CN120098964B (zh) * 2025-03-05 2026-01-02 江苏百时美生物科技有限公司 高效热稳定的核糖核酸酶SiRe_0902在特异性识别GG位点中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5459392A (en) 1977-10-14 1979-05-12 Rikagaku Kenkyusho Novel nuclease and its preparation
US20060057590A1 (en) 2004-09-14 2006-03-16 Azeddine Si-Ammour RNA probes

Also Published As

Publication number Publication date
EP2718431B1 (en) 2015-10-28
JP6075892B2 (ja) 2017-02-08
AU2012267271B2 (en) 2015-06-04
WO2012169917A1 (en) 2012-12-13
CA2837143A1 (en) 2012-12-13
PL222511B1 (pl) 2016-08-31
CA2837143C (en) 2016-01-05
US9238805B2 (en) 2016-01-19
CN103764821B (zh) 2016-04-27
ES2555661T3 (es) 2016-01-07
CN103764821A (zh) 2014-04-30
US20140087427A1 (en) 2014-03-27
PL395178A1 (pl) 2012-12-17
JP2014518641A (ja) 2014-08-07
KR20140045371A (ko) 2014-04-16
AU2012267271A1 (en) 2013-12-12
EP2718431A1 (en) 2014-04-16

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