JP6075892B2 - 二本鎖ｒｎａエンドリボヌクレアーゼ - Google Patents

二本鎖ｒｎａエンドリボヌクレアーゼ Download PDF

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JP6075892B2
JP6075892B2 JP2014514835A JP2014514835A JP6075892B2 JP 6075892 B2 JP6075892 B2 JP 6075892B2 JP 2014514835 A JP2014514835 A JP 2014514835A JP 2014514835 A JP2014514835 A JP 2014514835A JP 6075892 B2 JP6075892 B2 JP 6075892B2
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double
stranded rna
endoribonuclease
sequence
seq
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JP2014514835A
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Japanese (ja)
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JP2014518641A5 (https=
JP2014518641A (ja
Inventor
ヤヌスズ マレク ブジニキ
ヤヌスズ マレク ブジニキ
イェルジ スコウロネク，クリストフ
イェルジ スコウロネク，クリストフ
ピアンカ，ダリウス
アグニエスカ スレジ，アガタ
アグニエスカ スレジ，アガタ
Original Assignee
ミエドジナロドウィ インスティタット バイオロジーモレキュラーネイ アイ コモルコウェイ
ミエドジナロドウィ インスティタット バイオロジーモレキュラーネイ アイ コモルコウェイ
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003—Ribonuclease III (3.1.26.3)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2014514835A 2011-06-08 2012-06-07 二本鎖ｒｎａエンドリボヌクレアーゼ Expired - Fee Related JP6075892B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161494574P 2011-06-08 2011-06-08
PL395178A PL222511B1 (pl) 2011-06-08 2011-06-08 Endorybonukleazy dsRNA
PLP.395178 2011-06-08
US61/494,574 2011-06-08
PCT/PL2012/050020 WO2012169917A1 (en) 2011-06-08 2012-06-07 Dsrna endoribonucleases

Publications (3)

Publication Number Publication Date
JP2014518641A JP2014518641A (ja) 2014-08-07
JP2014518641A5 JP2014518641A5 (https=) 2016-03-17
JP6075892B2 true JP6075892B2 (ja) 2017-02-08

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ID=47296271

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JP2014514835A Expired - Fee Related JP6075892B2 (ja) 2011-06-08 2012-06-07 二本鎖ｒｎａエンドリボヌクレアーゼ

Country Status (11)

Country Link
US (1) US9238805B2 (https=)
EP (1) EP2718431B1 (https=)
JP (1) JP6075892B2 (https=)
KR (1) KR20140045371A (https=)
CN (1) CN103764821B (https=)
AU (1) AU2012267271B2 (https=)
CA (1) CA2837143C (https=)
DK (1) DK2718431T3 (https=)
ES (1) ES2555661T3 (https=)
PL (1) PL222511B1 (https=)
WO (1) WO2012169917A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013055995A2 (en) 2011-10-14 2013-04-18 President And Fellows Of Harvard College Sequencing by structure assembly
EP4697020A2 (en) 2011-12-22 2026-02-18 President And Fellows Of Harvard College Compositions and methods for analyte detection
ES2991004T3 (es) 2011-12-22 2024-12-02 Harvard College Métodos para la detección de analitos
US9914967B2 (en) 2012-06-05 2018-03-13 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using DNA origami probes
EP3578666A1 (en) 2013-03-12 2019-12-11 President and Fellows of Harvard College Method of generating a three-dimensional nucleic acid containing matrix
EP4596565A3 (en) 2013-06-04 2025-11-05 President And Fellows Of Harvard College Rna-guided transcriptional regulation
WO2016007839A1 (en) 2014-07-11 2016-01-14 President And Fellows Of Harvard College Methods for high-throughput labelling and detection of biological features in situ using microscopy
CN104306989A (zh) * 2014-09-27 2015-01-28 郭和友 一种利用切割酶治疗细菌方法
JP6882282B2 (ja) 2015-11-03 2021-06-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 三次元核酸含有マトリックスの立体撮像のための方法と装置
PL415883A1 (pl) * 2016-01-22 2017-07-31 Międzynarodowy Instytut Biologii Molekularnej I Komórkowej RNazy MiniIII, sposoby zmiany specyficzności cięcia sekwencji RNA przez RNazy MiniIII oraz ich zastosowania
CN109415761B (zh) 2016-04-25 2022-09-20 哈佛学院董事及会员团体 用于原位分子检测的杂交链反应方法
CN109923216B (zh) 2016-08-31 2024-08-02 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
GB2570412A (en) 2016-08-31 2019-07-24 Harvard College Methods of generating libraries of nucleic acid sequences for detection via fluorescent in situ sequencing
WO2018134386A1 (en) * 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
CN112770776B (zh) 2018-07-30 2025-08-19 瑞德库尔有限责任公司 用于样品处理或分析的方法和系统
WO2020076976A1 (en) 2018-10-10 2020-04-16 Readcoor, Inc. Three-dimensional spatial molecular indexing
WO2021155063A1 (en) 2020-01-29 2021-08-05 Readcoor, Llc Compositions and methods for analyte detection
US20220049303A1 (en) 2020-08-17 2022-02-17 Readcoor, Llc Methods and systems for spatial mapping of genetic variants
CN120098964B (zh) * 2025-03-05 2026-01-02 江苏百时美生物科技有限公司 高效热稳定的核糖核酸酶SiRe_0902在特异性识别GG位点中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5459392A (en) 1977-10-14 1979-05-12 Rikagaku Kenkyusho Novel nuclease and its preparation
US20060057590A1 (en) 2004-09-14 2006-03-16 Azeddine Si-Ammour RNA probes

Also Published As

Publication number Publication date
EP2718431B1 (en) 2015-10-28
AU2012267271B2 (en) 2015-06-04
WO2012169917A1 (en) 2012-12-13
DK2718431T3 (en) 2015-11-16
CA2837143A1 (en) 2012-12-13
PL222511B1 (pl) 2016-08-31
CA2837143C (en) 2016-01-05
US9238805B2 (en) 2016-01-19
CN103764821B (zh) 2016-04-27
ES2555661T3 (es) 2016-01-07
CN103764821A (zh) 2014-04-30
US20140087427A1 (en) 2014-03-27
PL395178A1 (pl) 2012-12-17
JP2014518641A (ja) 2014-08-07
KR20140045371A (ko) 2014-04-16
AU2012267271A1 (en) 2013-12-12
EP2718431A1 (en) 2014-04-16

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