DK2284167T4 - Krystallinsk form af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid - Google Patents

Krystallinsk form af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid Download PDF

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Publication number
DK2284167T4
DK2284167T4 DK10173956.3T DK10173956T DK2284167T4 DK 2284167 T4 DK2284167 T4 DK 2284167T4 DK 10173956 T DK10173956 T DK 10173956T DK 2284167 T4 DK2284167 T4 DK 2284167T4
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Prior art keywords
methyl
ylamino
benzamide
imidazol
pyrimidin
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DK10173956.3T
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English (en)
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DK2284167T3 (da
Inventor
Paul W Manley
Wen-Chung Shieh
Paul Allen Sutton
Piotr H Karpinski
Raeann Wu
Stéphanie Monnier
Jörg Brozio
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Novartis Ag
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK10173956.3T 2005-07-20 2006-07-18 Krystallinsk form af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid DK2284167T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70140505P 2005-07-20 2005-07-20
US71621405P 2005-09-12 2005-09-12
EP06800109A EP1912973B1 (en) 2005-07-20 2006-07-18 Crystalline forms of 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Publications (2)

Publication Number Publication Date
DK2284167T3 DK2284167T3 (da) 2017-05-01
DK2284167T4 true DK2284167T4 (da) 2020-03-02

Family

ID=37451227

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06800109.8T DK1912973T3 (da) 2005-07-20 2006-07-18 Krystallinske former af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid
DK10173956.3T DK2284167T4 (da) 2005-07-20 2006-07-18 Krystallinsk form af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06800109.8T DK1912973T3 (da) 2005-07-20 2006-07-18 Krystallinske former af 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluormethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamid

Country Status (43)

Country Link
US (4) US8343984B2 (da)
EP (5) EP1912973B1 (da)
JP (3) JP5289948B2 (da)
KR (3) KR101651288B1 (da)
CN (2) CN102358736A (da)
AR (1) AR054846A1 (da)
AU (3) AU2006276204A1 (da)
BR (1) BRPI0613615B1 (da)
CA (1) CA2614334C (da)
CR (1) CR9657A (da)
CU (1) CU23916B1 (da)
CY (2) CY1113076T1 (da)
DK (2) DK1912973T3 (da)
EA (2) EA016856B1 (da)
EC (1) ECSP088119A (da)
ES (3) ES2648288T3 (da)
GE (1) GEP20115302B (da)
GT (1) GT200600315A (da)
HK (1) HK1116783A1 (da)
HN (1) HN2008000311A (da)
HR (2) HRP20120573T1 (da)
HU (1) HUE031791T2 (da)
IL (2) IL188189A0 (da)
JO (1) JO3308B1 (da)
LT (1) LT2284167T (da)
MA (1) MA29626B1 (da)
MX (1) MX2008000899A (da)
MY (1) MY148554A (da)
NI (1) NI200800017A (da)
NO (1) NO341930B1 (da)
NZ (1) NZ564409A (da)
PE (1) PE20070214A1 (da)
PH (1) PH12013501590A1 (da)
PL (2) PL1912973T3 (da)
PT (2) PT2284167T (da)
RS (1) RS55929B2 (da)
SG (1) SG163620A1 (da)
SI (2) SI2284167T2 (da)
SM (1) SMAP200800011A (da)
TN (1) TNSN08029A1 (da)
TW (1) TWI406661B (da)
UA (1) UA94234C2 (da)
WO (1) WO2007015870A2 (da)

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KR20130077915A (ko) 2013-07-09
CA2614334A1 (en) 2007-02-08
US8829015B2 (en) 2014-09-09
PT1912973E (pt) 2012-09-03
MX2008000899A (es) 2008-03-18
CR9657A (es) 2008-04-16
EP1912973B1 (en) 2012-06-13
EP2543665A2 (en) 2013-01-09
HRP20170634T1 (hr) 2017-06-30
EA200800201A1 (ru) 2008-06-30
EP2284167B2 (en) 2019-11-27
EP2284168A3 (en) 2011-04-13
PE20070214A1 (es) 2007-04-02
TW200740793A (en) 2007-11-01
EP2284167A3 (en) 2011-03-02
CN102358736A (zh) 2012-02-22
SMP200800011B (it) 2008-02-27
GEP20115302B (en) 2011-10-10
MY148554A (en) 2013-04-30
CA2614334C (en) 2015-04-21
PH12013501590A1 (en) 2015-09-21
AR054846A1 (es) 2007-07-18
PL1912973T3 (pl) 2012-09-28
PL2284167T3 (pl) 2017-07-31
US20130023548A1 (en) 2013-01-24
UA94234C2 (uk) 2011-04-26
ECSP088119A (es) 2008-02-20
US8343984B2 (en) 2013-01-01
EP2543665A3 (en) 2013-05-29
JO3308B1 (ar) 2018-09-16
US20130165465A1 (en) 2013-06-27
AU2011202047A1 (en) 2011-05-26
ES2623608T3 (es) 2017-07-11
IL214659A0 (en) 2011-09-27
EP2284167A2 (en) 2011-02-16
RS55929B1 (sr) 2017-09-29
KR20080027853A (ko) 2008-03-28
AU2012201453B2 (en) 2013-09-05
ES2623608T5 (es) 2020-06-18
US20140343087A1 (en) 2014-11-20
EP2535337A1 (en) 2012-12-19
SMAP200800011A (it) 2008-02-27
BRPI0613615B1 (pt) 2022-02-08
SI2284167T2 (sl) 2020-03-31
EP2284167B1 (en) 2017-02-01
HN2008000311A (es) 2011-01-24
JP2014221831A (ja) 2014-11-27
HRP20170634T4 (hr) 2020-02-07
JP5798101B2 (ja) 2015-10-21
WO2007015870A2 (en) 2007-02-08
AU2006276204A1 (en) 2007-02-08
GT200600315A (es) 2007-03-19
PL2284167T5 (pl) 2020-07-27
CU23916B1 (es) 2013-07-31
JP2013018789A (ja) 2013-01-31
JP5289948B2 (ja) 2013-09-11
EP1912973A2 (en) 2008-04-23
ES2648288T3 (es) 2017-12-29
CU20080006A7 (es) 2011-02-24
PT2284167T (pt) 2017-05-15
EP2284168A2 (en) 2011-02-16
MA29626B1 (fr) 2008-07-01
NO341930B1 (no) 2018-02-19
HRP20120573T1 (hr) 2012-08-31
LT2284167T (lt) 2017-04-25
TWI406661B (zh) 2013-09-01
NO20080820L (no) 2008-04-15
EA013464B1 (ru) 2010-04-30
JP2009502795A (ja) 2009-01-29
SG163620A1 (en) 2010-08-30
TNSN08029A1 (en) 2009-07-14
RS55929B2 (sr) 2020-12-31
WO2007015870A3 (en) 2007-06-07
BRPI0613615A2 (pt) 2011-01-18
AU2012201453A1 (en) 2012-04-05
CY1113076T1 (el) 2016-04-13
EA016856B1 (ru) 2012-08-30
NI200800017A (es) 2009-03-03
ES2386974T3 (es) 2012-09-10
DK2284167T3 (da) 2017-05-01
KR20130085444A (ko) 2013-07-29
AU2012201453C1 (en) 2024-05-23
CN103804356A (zh) 2014-05-21
NZ564409A (en) 2011-07-29
SI2284167T1 (sl) 2017-05-31
EP2535337B1 (en) 2017-08-23
IL188189A0 (en) 2008-03-20
HUE031791T2 (en) 2017-08-28
EA201000145A1 (ru) 2010-06-30
DK1912973T3 (da) 2012-07-23
HK1116783A1 (da) 2009-01-02
US20080269269A1 (en) 2008-10-30
KR101651288B1 (ko) 2016-08-25
US8415363B2 (en) 2013-04-09
SI1912973T1 (sl) 2012-08-31
CY1119624T1 (el) 2018-04-04

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