AR054846A1 - Formas cristalinas de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4- piridin-3-il-pirimidin-2- ilamino)-benzamida - Google Patents

Formas cristalinas de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4- piridin-3-il-pirimidin-2- ilamino)-benzamida

Info

Publication number
AR054846A1
AR054846A1 ARP060103070A ARP060103070A AR054846A1 AR 054846 A1 AR054846 A1 AR 054846A1 AR P060103070 A ARP060103070 A AR P060103070A AR P060103070 A ARP060103070 A AR P060103070A AR 054846 A1 AR054846 A1 AR 054846A1
Authority
AR
Argentina
Prior art keywords
methyl
imidazol
phenyl
benzamida
trifluorometil
Prior art date
Application number
ARP060103070A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37451227&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR054846(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR054846A1 publication Critical patent/AR054846A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Sales de las mismas y composiciones farmacéuticas que las contienen. Reivindicacion 1: Una forma cristalina sustancialmente pura A de 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida como base libre. Reivindicacion 4: Una forma cristalina sustancialmente pura B de 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida como base libre.
ARP060103070A 2005-07-20 2006-07-18 Formas cristalinas de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4- piridin-3-il-pirimidin-2- ilamino)-benzamida AR054846A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70140505P 2005-07-20 2005-07-20
US71621405P 2005-09-12 2005-09-12

Publications (1)

Publication Number Publication Date
AR054846A1 true AR054846A1 (es) 2007-07-18

Family

ID=37451227

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060103070A AR054846A1 (es) 2005-07-20 2006-07-18 Formas cristalinas de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4- piridin-3-il-pirimidin-2- ilamino)-benzamida

Country Status (43)

Country Link
US (4) US8343984B2 (es)
EP (5) EP2543665A3 (es)
JP (3) JP5289948B2 (es)
KR (3) KR20130077915A (es)
CN (2) CN103804356A (es)
AR (1) AR054846A1 (es)
AU (3) AU2006276204A1 (es)
BR (1) BRPI0613615B1 (es)
CA (1) CA2614334C (es)
CR (1) CR9657A (es)
CU (1) CU23916B1 (es)
CY (2) CY1113076T1 (es)
DK (2) DK2284167T4 (es)
EA (2) EA013464B1 (es)
EC (1) ECSP088119A (es)
ES (3) ES2648288T3 (es)
GE (1) GEP20115302B (es)
GT (1) GT200600315A (es)
HK (1) HK1116783A1 (es)
HN (1) HN2008000311A (es)
HR (2) HRP20120573T1 (es)
HU (1) HUE031791T2 (es)
IL (2) IL188189A0 (es)
JO (1) JO3308B1 (es)
LT (1) LT2284167T (es)
MA (1) MA29626B1 (es)
MX (1) MX2008000899A (es)
MY (1) MY148554A (es)
NI (1) NI200800017A (es)
NO (1) NO341930B1 (es)
NZ (1) NZ564409A (es)
PE (1) PE20070214A1 (es)
PH (1) PH12013501590A1 (es)
PL (2) PL2284167T5 (es)
PT (2) PT1912973E (es)
RS (1) RS55929B2 (es)
SG (1) SG163620A1 (es)
SI (2) SI2284167T2 (es)
SM (1) SMP200800011B (es)
TN (1) TNSN08029A1 (es)
TW (1) TWI406661B (es)
UA (1) UA94234C2 (es)
WO (1) WO2007015870A2 (es)

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GT200600315A (es) 2005-07-20 2007-03-19 Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida
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Publication number Publication date
CA2614334C (en) 2015-04-21
EP2543665A3 (en) 2013-05-29
JP5289948B2 (ja) 2013-09-11
SI2284167T2 (sl) 2020-03-31
JP2014221831A (ja) 2014-11-27
ES2623608T3 (es) 2017-07-11
JP2013018789A (ja) 2013-01-31
PT1912973E (pt) 2012-09-03
HRP20170634T4 (hr) 2020-02-07
IL188189A0 (en) 2008-03-20
GT200600315A (es) 2007-03-19
US20130023548A1 (en) 2013-01-24
HN2008000311A (es) 2011-01-24
DK2284167T4 (da) 2020-03-02
CY1113076T1 (el) 2016-04-13
HRP20120573T1 (hr) 2012-08-31
ES2386974T3 (es) 2012-09-10
EP2535337A1 (en) 2012-12-19
UA94234C2 (uk) 2011-04-26
HUE031791T2 (en) 2017-08-28
EP1912973B1 (en) 2012-06-13
US8415363B2 (en) 2013-04-09
CU23916B1 (es) 2013-07-31
JO3308B1 (ar) 2018-09-16
LT2284167T (lt) 2017-04-25
SMAP200800011A (it) 2008-02-27
EP2284168A2 (en) 2011-02-16
BRPI0613615B1 (pt) 2022-02-08
MA29626B1 (fr) 2008-07-01
EP2284167B2 (en) 2019-11-27
EA016856B1 (ru) 2012-08-30
HRP20170634T1 (hr) 2017-06-30
EP2284167B1 (en) 2017-02-01
EP2543665A2 (en) 2013-01-09
EP2284168A3 (en) 2011-04-13
US20130165465A1 (en) 2013-06-27
JP5798101B2 (ja) 2015-10-21
CA2614334A1 (en) 2007-02-08
EA013464B1 (ru) 2010-04-30
CU20080006A7 (es) 2011-02-24
AU2012201453A1 (en) 2012-04-05
NO341930B1 (no) 2018-02-19
BRPI0613615A2 (pt) 2011-01-18
RS55929B1 (sr) 2017-09-29
TW200740793A (en) 2007-11-01
EP2284167A2 (en) 2011-02-16
CR9657A (es) 2008-04-16
TWI406661B (zh) 2013-09-01
SMP200800011B (it) 2008-02-27
AU2011202047A1 (en) 2011-05-26
MY148554A (en) 2013-04-30
TNSN08029A1 (en) 2009-07-14
ES2648288T3 (es) 2017-12-29
EP2284167A3 (en) 2011-03-02
US8343984B2 (en) 2013-01-01
NI200800017A (es) 2009-03-03
JP2009502795A (ja) 2009-01-29
SG163620A1 (en) 2010-08-30
KR20080027853A (ko) 2008-03-28
PH12013501590A1 (en) 2015-09-21
NO20080820L (no) 2008-04-15
EP2535337B1 (en) 2017-08-23
KR101651288B1 (ko) 2016-08-25
EA200800201A1 (ru) 2008-06-30
NZ564409A (en) 2011-07-29
ES2623608T5 (es) 2020-06-18
AU2006276204A1 (en) 2007-02-08
DK1912973T3 (da) 2012-07-23
RS55929B2 (sr) 2020-12-31
KR20130085444A (ko) 2013-07-29
DK2284167T3 (en) 2017-05-01
EP1912973A2 (en) 2008-04-23
WO2007015870A3 (en) 2007-06-07
EA201000145A1 (ru) 2010-06-30
WO2007015870A2 (en) 2007-02-08
ECSP088119A (es) 2008-02-20
HK1116783A1 (es) 2009-01-02
GEP20115302B (en) 2011-10-10
KR20130077915A (ko) 2013-07-09
IL214659A0 (en) 2011-09-27
MX2008000899A (es) 2008-03-18
US20080269269A1 (en) 2008-10-30
AU2012201453C1 (en) 2024-05-23
CN103804356A (zh) 2014-05-21
PL2284167T5 (pl) 2020-07-27
PT2284167T (pt) 2017-05-15
CY1119624T1 (el) 2018-04-04
PL2284167T3 (pl) 2017-07-31
PL1912973T3 (pl) 2012-09-28
CN102358736A (zh) 2012-02-22
AU2012201453B2 (en) 2013-09-05
US20140343087A1 (en) 2014-11-20
SI2284167T1 (sl) 2017-05-31
SI1912973T1 (sl) 2012-08-31
PE20070214A1 (es) 2007-04-02
US8829015B2 (en) 2014-09-09

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