ECSP088118A - Sales de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida - Google Patents

Sales de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida

Info

Publication number
ECSP088118A
ECSP088118A EC2008008118A ECSP088118A ECSP088118A EC SP088118 A ECSP088118 A EC SP088118A EC 2008008118 A EC2008008118 A EC 2008008118A EC SP088118 A ECSP088118 A EC SP088118A EC SP088118 A ECSP088118 A EC SP088118A
Authority
EC
Ecuador
Prior art keywords
methyl
imidazol
phenyl
salts
benzamida
Prior art date
Application number
EC2008008118A
Other languages
English (en)
Inventor
Paul William Manley
Piotr Karpinski
Paul Allen Sutton
Wen-Chung Shieh
Raeann Wu
Stephanie Monnier
Joerg Brozio
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37398525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088118(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP088118A publication Critical patent/ECSP088118A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Las sales de 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida son preparadas mediante varios procesos.
EC2008008118A 2005-07-20 2008-01-18 Sales de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida ECSP088118A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70140605P 2005-07-20 2005-07-20
US71621305P 2005-09-12 2005-09-12

Publications (1)

Publication Number Publication Date
ECSP088118A true ECSP088118A (es) 2008-02-20

Family

ID=37398525

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008118A ECSP088118A (es) 2005-07-20 2008-01-18 Sales de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida

Country Status (34)

Country Link
US (4) US8163904B2 (es)
EP (2) EP1910336B1 (es)
JP (1) JP5129132B2 (es)
KR (3) KR20140047737A (es)
CN (1) CN102267981A (es)
AR (1) AR057467A1 (es)
AT (1) ATE514689T1 (es)
AU (2) AU2006276205B2 (es)
BR (1) BRPI0613605A2 (es)
CA (2) CA2823946C (es)
CY (1) CY1111772T1 (es)
DK (1) DK1910336T3 (es)
EC (1) ECSP088118A (es)
ES (1) ES2634291T3 (es)
GT (1) GT200600316A (es)
HK (1) HK1116778A1 (es)
HR (1) HRP20110639T1 (es)
IL (1) IL187787A (es)
JO (1) JO2757B1 (es)
MA (1) MA29686B1 (es)
MX (1) MX2008000892A (es)
MY (1) MY149889A (es)
NO (1) NO341313B1 (es)
NZ (2) NZ591142A (es)
PE (1) PE20070241A1 (es)
PL (1) PL1910336T3 (es)
PT (1) PT1910336E (es)
RU (4) RU2483065C2 (es)
SG (1) SG170772A1 (es)
SI (1) SI1910336T1 (es)
TN (1) TNSN08028A1 (es)
TW (1) TWI455934B (es)
UY (1) UY29683A1 (es)
WO (1) WO2007015871A1 (es)

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WO2013063003A1 (en) 2011-10-28 2013-05-02 Novartis Ag Method of treating gastrointestinal stromal tumors
CA2853095A1 (en) 2011-10-28 2013-05-02 Novartis Ag Method of treating gastrointestinal stromal tumors
SG11201401476TA (en) 2011-11-14 2014-10-30 Novartis Ag Immediate release 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-[5-(4-methyl- 1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide formulation
MX2015000457A (es) 2012-07-11 2015-04-08 Novartis Ag Metodo de tratamiento de tumores del estroma gastrointestinal.
AU2013332205B2 (en) * 2012-10-15 2017-08-31 Apotex Inc. Solid forms of Nilotinib hydrochloride
RU2652121C2 (ru) * 2012-10-19 2018-04-25 Басф Се Многокомпонентная кристаллическая система, содержащая нилотиниб и выбранные сокристаллообразователи
EP2792360A1 (en) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV
EP2989090A4 (en) 2013-04-24 2017-01-18 Dr. Reddy's Laboratories Ltd. Polymorphic forms of nilotinib hydrochloride
RU2551359C9 (ru) * 2013-11-28 2021-08-20 Общество с ограниченной ответственностью "Мамонт Фарм" Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе
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WO2016020891A1 (en) 2014-08-08 2016-02-11 Dr. Reddy’S Laboratories Limited Process for the preparation of polymorphic forms of nilotinib
ES2908457T3 (es) * 2014-08-11 2022-04-29 Sun Pharmaceutical Ind Ltd Novedosas sales de nilotinib y polimorfos de las mismas
EP3271351A1 (en) 2015-03-20 2018-01-24 Cipla Limited Novel polymorphic form x of nilotinib dihydrochloride hydrate
WO2017129694A1 (en) 2016-01-26 2017-08-03 Farma Grs, D.O.O. Nilotinib dinitrate (v) and crystalline forms thereof
WO2017149550A1 (en) * 2016-03-02 2017-09-08 Msn Laboratories Private Limited Amorphous form of 4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide
LT3430004T (lt) 2016-03-14 2020-11-25 Pliva Hrvatska D.O.O. Nilotinibo druskų kietosios būsenos formos
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CN116808044A (zh) 2018-06-15 2023-09-29 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
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GT200600315A (es) 2005-07-20 2007-03-19 Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida

Also Published As

Publication number Publication date
MA29686B1 (fr) 2008-08-01
CN102267981A (zh) 2011-12-07
DK1910336T3 (da) 2011-10-03
HRP20110639T1 (hr) 2011-10-31
CA2823946C (en) 2015-12-29
MX2008000892A (es) 2008-03-18
AU2006276205A1 (en) 2007-02-08
CA2615669A1 (en) 2007-02-08
AU2006276205B2 (en) 2010-08-19
ES2634291T3 (es) 2017-09-27
EP1910336B1 (en) 2011-06-29
RU2008105827A (ru) 2009-08-27
US8580806B2 (en) 2013-11-12
TW200800950A (en) 2008-01-01
NZ564182A (en) 2011-03-31
WO2007015871A1 (en) 2007-02-08
KR20140047737A (ko) 2014-04-22
KR101755137B1 (ko) 2017-07-06
RU2011120363A (ru) 2012-11-27
SG170772A1 (en) 2011-05-30
AU2010241419A1 (en) 2010-12-02
JP2009502796A (ja) 2009-01-29
RU2509767C1 (ru) 2014-03-20
PE20070241A1 (es) 2007-03-22
EP1910336A1 (en) 2008-04-16
RU2013101749A (ru) 2014-07-27
RU2483065C2 (ru) 2013-05-27
AU2010241419C1 (en) 2024-05-23
UY29683A1 (es) 2007-02-28
CY1111772T1 (el) 2015-10-07
BRPI0613605A2 (pt) 2011-01-18
NO20080897L (no) 2008-02-20
GT200600316A (es) 2007-04-02
AU2010241419B2 (en) 2012-03-29
US8163904B2 (en) 2012-04-24
HK1116778A1 (es) 2009-01-02
TWI455934B (zh) 2014-10-11
KR20080027855A (ko) 2008-03-28
CA2823946A1 (en) 2007-02-08
TNSN08028A1 (en) 2009-07-14
AR057467A1 (es) 2007-12-05
IL187787A (en) 2012-07-31
RU2434864C2 (ru) 2011-11-27
RU2605551C2 (ru) 2016-12-20
US20120270891A1 (en) 2012-10-25
EP2186808A1 (en) 2010-05-19
US20130137712A1 (en) 2013-05-30
NO341313B1 (no) 2017-10-09
PT1910336E (pt) 2011-09-05
CA2615669C (en) 2013-11-12
JP5129132B2 (ja) 2013-01-23
EP2186808B1 (en) 2017-04-19
US20140038994A1 (en) 2014-02-06
US9163005B2 (en) 2015-10-20
IL187787A0 (en) 2008-08-07
US8389537B2 (en) 2013-03-05
MY149889A (en) 2013-10-31
PL1910336T3 (pl) 2011-11-30
NZ591142A (en) 2012-09-28
ATE514689T1 (de) 2011-07-15
JO2757B1 (en) 2014-03-15
SI1910336T1 (sl) 2011-10-28
KR20150100946A (ko) 2015-09-02
US20080200487A1 (en) 2008-08-21

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