MA29686B1 - Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide - Google Patents

Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Info

Publication number
MA29686B1
MA29686B1 MA30563A MA30563A MA29686B1 MA 29686 B1 MA29686 B1 MA 29686B1 MA 30563 A MA30563 A MA 30563A MA 30563 A MA30563 A MA 30563A MA 29686 B1 MA29686 B1 MA 29686B1
Authority
MA
Morocco
Prior art keywords
methyl
ylamino
imidazol
pyrimidin
pyridin
Prior art date
Application number
MA30563A
Other languages
English (en)
Inventor
Paul W Manley
Wen-Chung Shieh
Paul Allen Sutton
Piotr H Karpinski
Raeann Wu
Stephanie Monnier
Joerg Brozio
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37398525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29686(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29686B1 publication Critical patent/MA29686B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Sels de 4-méthyl-N-[3-(4-méthyl-imidazol-1-yl)-5-trifluorométhyl-phényl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide préparés à l'aide de divers procédés.
MA30563A 2005-07-20 2008-01-09 Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide MA29686B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70140605P 2005-07-20 2005-07-20
US71621305P 2005-09-12 2005-09-12

Publications (1)

Publication Number Publication Date
MA29686B1 true MA29686B1 (fr) 2008-08-01

Family

ID=37398525

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30563A MA29686B1 (fr) 2005-07-20 2008-01-09 Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Country Status (34)

Country Link
US (4) US8163904B2 (fr)
EP (2) EP1910336B1 (fr)
JP (1) JP5129132B2 (fr)
KR (3) KR20080027855A (fr)
CN (1) CN102267981A (fr)
AR (1) AR057467A1 (fr)
AT (1) ATE514689T1 (fr)
AU (2) AU2006276205C1 (fr)
BR (1) BRPI0613605A2 (fr)
CA (2) CA2823946C (fr)
CY (1) CY1111772T1 (fr)
DK (1) DK1910336T3 (fr)
EC (1) ECSP088118A (fr)
ES (1) ES2634291T3 (fr)
GT (1) GT200600316A (fr)
HK (1) HK1116778A1 (fr)
HR (1) HRP20110639T1 (fr)
IL (1) IL187787A (fr)
JO (1) JO2757B1 (fr)
MA (1) MA29686B1 (fr)
MX (1) MX2008000892A (fr)
MY (1) MY149889A (fr)
NO (1) NO341313B1 (fr)
NZ (2) NZ564182A (fr)
PE (1) PE20070241A1 (fr)
PL (1) PL1910336T3 (fr)
PT (1) PT1910336E (fr)
RU (4) RU2483065C2 (fr)
SG (1) SG170772A1 (fr)
SI (1) SI1910336T1 (fr)
TN (1) TNSN08028A1 (fr)
TW (1) TWI455934B (fr)
UY (1) UY29683A1 (fr)
WO (1) WO2007015871A1 (fr)

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EP2770999A1 (fr) 2011-10-28 2014-09-03 Novartis AG Procédé de traitement de tumeurs stromales gastro-intestinales
WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
WO2013074432A1 (fr) 2011-11-14 2013-05-23 Novartis Ag Formulation à libération immédiate de 4-méthyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-[5-(4-méthyl- 1h-imidazol-1-yl)-3-(trifluorométhyl)phényl]benzamide
US20150202203A1 (en) 2012-07-11 2015-07-23 Novartis Ag Method of Treating Gastrointestinal Stromal Tumors
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EP2909191B1 (fr) * 2012-10-19 2019-03-20 Basf Se Système cristallin multicomposant comprenant du nilotinib et des formateurs de co-cristal sélectionnés
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CN105324375A (zh) 2013-04-24 2016-02-10 雷迪博士实验室有限公司 盐酸尼洛替尼的多晶型形式
RU2551359C9 (ru) * 2013-11-28 2021-08-20 Общество с ограниченной ответственностью "Мамонт Фарм" Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе
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Also Published As

Publication number Publication date
HRP20110639T1 (hr) 2011-10-31
AU2010241419A1 (en) 2010-12-02
NZ564182A (en) 2011-03-31
ES2634291T3 (es) 2017-09-27
US8580806B2 (en) 2013-11-12
NO20080897L (no) 2008-02-20
KR20140047737A (ko) 2014-04-22
RU2434864C2 (ru) 2011-11-27
RU2605551C2 (ru) 2016-12-20
AU2010241419C1 (en) 2024-05-23
US20140038994A1 (en) 2014-02-06
HK1116778A1 (fr) 2009-01-02
GT200600316A (es) 2007-04-02
US8163904B2 (en) 2012-04-24
US20080200487A1 (en) 2008-08-21
CA2823946C (fr) 2015-12-29
IL187787A (en) 2012-07-31
CN102267981A (zh) 2011-12-07
AU2010241419B2 (en) 2012-03-29
EP1910336A1 (fr) 2008-04-16
AU2006276205C1 (en) 2024-08-01
JP2009502796A (ja) 2009-01-29
JP5129132B2 (ja) 2013-01-23
EP2186808A1 (fr) 2010-05-19
EP1910336B1 (fr) 2011-06-29
MY149889A (en) 2013-10-31
KR101755137B1 (ko) 2017-07-06
RU2509767C1 (ru) 2014-03-20
ECSP088118A (es) 2008-02-20
NO341313B1 (no) 2017-10-09
PT1910336E (pt) 2011-09-05
RU2008105827A (ru) 2009-08-27
RU2013101749A (ru) 2014-07-27
NZ591142A (en) 2012-09-28
UY29683A1 (es) 2007-02-28
MX2008000892A (es) 2008-03-18
US8389537B2 (en) 2013-03-05
TW200800950A (en) 2008-01-01
KR20150100946A (ko) 2015-09-02
US20120270891A1 (en) 2012-10-25
RU2483065C2 (ru) 2013-05-27
DK1910336T3 (da) 2011-10-03
KR20080027855A (ko) 2008-03-28
TWI455934B (zh) 2014-10-11
PE20070241A1 (es) 2007-03-22
CA2615669A1 (fr) 2007-02-08
AU2006276205B2 (en) 2010-08-19
US20130137712A1 (en) 2013-05-30
CY1111772T1 (el) 2015-10-07
EP2186808B1 (fr) 2017-04-19
AU2006276205A1 (en) 2007-02-08
AR057467A1 (es) 2007-12-05
IL187787A0 (en) 2008-08-07
PL1910336T3 (pl) 2011-11-30
JO2757B1 (en) 2014-03-15
SG170772A1 (en) 2011-05-30
WO2007015871A1 (fr) 2007-02-08
RU2011120363A (ru) 2012-11-27
CA2615669C (fr) 2013-11-12
TNSN08028A1 (en) 2009-07-14
SI1910336T1 (sl) 2011-10-28
ATE514689T1 (de) 2011-07-15
CA2823946A1 (fr) 2007-02-08
US9163005B2 (en) 2015-10-20
BRPI0613605A2 (pt) 2011-01-18

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