DK175635B1 - Hybridomacellelinier, der producerer monoklonale antistoffer, som reagerer med nye mucinepitoper - Google Patents

Hybridomacellelinier, der producerer monoklonale antistoffer, som reagerer med nye mucinepitoper Download PDF

Info

Publication number
DK175635B1
DK175635B1 DK198706062A DK606287A DK175635B1 DK 175635 B1 DK175635 B1 DK 175635B1 DK 198706062 A DK198706062 A DK 198706062A DK 606287 A DK606287 A DK 606287A DK 175635 B1 DK175635 B1 DK 175635B1
Authority
DK
Denmark
Prior art keywords
antibody
antibodies
hybridoma cell
sample
cell line
Prior art date
Application number
DK198706062A
Other languages
Danish (da)
English (en)
Other versions
DK606287A (da
DK606287D0 (da
Inventor
Joseph P Brown
Diane Horn
Linsley Peter S
Original Assignee
Sanofi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26801637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK175635(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Inc filed Critical Sanofi Inc
Publication of DK606287D0 publication Critical patent/DK606287D0/da
Publication of DK606287A publication Critical patent/DK606287A/da
Application granted granted Critical
Publication of DK175635B1 publication Critical patent/DK175635B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023Lung
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015Breast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK198706062A 1986-11-19 1987-11-18 Hybridomacellelinier, der producerer monoklonale antistoffer, som reagerer med nye mucinepitoper DK175635B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93278186A 1986-11-19 1986-11-19
US93278186 1986-11-19
US10451187A 1987-10-08 1987-10-08
US10451187 1987-10-08

Publications (3)

Publication Number Publication Date
DK606287D0 DK606287D0 (da) 1987-11-18
DK606287A DK606287A (da) 1988-05-20
DK175635B1 true DK175635B1 (da) 2004-12-27

Family

ID=26801637

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198706062A DK175635B1 (da) 1986-11-19 1987-11-18 Hybridomacellelinier, der producerer monoklonale antistoffer, som reagerer med nye mucinepitoper

Country Status (17)

Country Link
US (1) US5849876A (ja)
EP (1) EP0268279B2 (ja)
JP (1) JP2597372B2 (ja)
KR (1) KR900007951B1 (ja)
AT (1) ATE130029T1 (ja)
AU (1) AU613590B2 (ja)
CA (1) CA1340815C (ja)
DE (1) DE3751585T3 (ja)
DK (1) DK175635B1 (ja)
ES (1) ES2080717T5 (ja)
GR (1) GR3018093T3 (ja)
HK (1) HK1007766A1 (ja)
IE (1) IE71154B1 (ja)
IL (1) IL84475A (ja)
NO (1) NO175944C (ja)
NZ (1) NZ222509A (ja)
PT (1) PT86180B (ja)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054438A (en) * 1987-01-07 2000-04-25 Imperial Cancer Research Technology Limited Nucleic acid fragments encoding portions of the core protein of the human mammary epithelial mucin
AU625856B2 (en) * 1987-07-15 1992-07-16 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Second generation monoclonal antibodies having binding specificity to tag-72 and human carcinomas and methods for employing the same
JPH02255097A (ja) * 1989-03-29 1990-10-15 Ikuo Yamashina 単クローン抗体nny128
EP0544898A1 (en) * 1991-06-26 1993-06-09 The Biomembrane Institute Early diagnosis of lung cancer using anti-carbohydrate antibody combinations
FR2697088B1 (fr) * 1992-10-15 1997-06-27 Lacassagne Centre Antoine Anticorps monoclonaux pour le diagnostic différentiel de cancers épithéliaux dans des épanchements séreux, hybridomes les secrétant et kit de diagnostic.
EP0695760A1 (en) * 1994-08-05 1996-02-07 F. Hoffmann-La Roche Ag Novel tumor marker for lung cancer
US6207805B1 (en) * 1997-07-18 2001-03-27 University Of Iowa Research Foundation Prostate cell surface antigen-specific antibodies
US6881405B2 (en) * 1998-06-15 2005-04-19 Altarex Medical Corp. Reagents and methods for inducing an immune response to prostate specific antigen
US8071072B2 (en) * 1999-10-08 2011-12-06 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US8048416B2 (en) 1999-10-08 2011-11-01 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US6657048B2 (en) * 1999-10-08 2003-12-02 Arius Research, Inc. Individualized anti-cancer antibodies
US20080124327A1 (en) * 1999-10-08 2008-05-29 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US6794494B1 (en) 2003-04-14 2004-09-21 Arius Research, Inc. Cancerous disease modifying antibodies
US7442776B2 (en) * 1999-10-08 2008-10-28 Young David S F Cancerous disease modifying antibodies
US7947496B2 (en) 1999-10-08 2011-05-24 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7252821B2 (en) * 1999-10-08 2007-08-07 Arius Research Inc. Cancerous disease modifying antibodies
US20040001789A1 (en) * 1999-10-08 2004-01-01 Young David S. F. Cytotoxicity mediation of cells evidencing surface expression of gp96 or precursors thereof
US7189397B2 (en) * 1999-10-08 2007-03-13 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20050100542A1 (en) * 1999-10-08 2005-05-12 Young David S. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7419792B2 (en) * 1999-10-08 2008-09-02 Arius Research Inc. Laminin Receptor 1 Precursor Protein (37LRP) epitope delineated by an Hepatocellular carcinoma specific antibody
US20090004103A1 (en) * 1999-10-08 2009-01-01 Young David S F Cytotoxicity mediation of cells evidencing surface expression of CD44
US6180357B1 (en) * 1999-10-08 2001-01-30 Arius Research, Inc. Individualized patient-specific anti-cancer antibodies
US7256271B2 (en) 2003-01-21 2007-08-14 Arius Research Inc. Cancerous disease modifying antibodies
US20040105816A1 (en) * 1999-10-08 2004-06-03 Young David S. F. Cancerous disease modifying antibodies
CA2408594A1 (en) * 2000-05-08 2001-11-15 Medarex, Inc. Human monoclonal antibodies to dendritic cells
US7361343B2 (en) * 2003-01-21 2008-04-22 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US7534429B2 (en) * 2000-11-29 2009-05-19 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US7431923B2 (en) * 2005-01-03 2008-10-07 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US7442777B2 (en) * 2000-11-29 2008-10-28 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US20060210474A1 (en) * 2000-11-29 2006-09-21 Young David S Cytotoxicity mediation of cells evidencing surface expression of CD63
US7009040B2 (en) * 2003-01-21 2006-03-07 Arius Research, Inc. Cancerous disease modifying antibodies
JP4473117B2 (ja) 2002-03-13 2010-06-02 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗αvβ6抗体
CN1756845A (zh) 2002-11-12 2006-04-05 A·B·德塞罗斯 腺病毒载体疫苗
US7488475B2 (en) 2003-01-21 2009-02-10 Arius Research, Inc. Antibody therapy of tumors
US7175846B2 (en) * 2003-01-21 2007-02-13 Arius Research Inc. Cancerous disease modifying antibodies
US7361342B2 (en) * 2003-01-21 2008-04-22 Arius Research Inc. Cancerous disease modifying antibodies
US7468254B2 (en) * 2003-01-21 2008-12-23 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of MCSP
US7393531B2 (en) 2003-01-21 2008-07-01 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of MCSP
US20080213169A1 (en) * 2003-04-14 2008-09-04 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of CD59
US7195764B2 (en) 2003-04-14 2007-03-27 Arius Research Inc. Cancerous disease modifying antibodies
US7399835B2 (en) * 2004-02-26 2008-07-15 Arius Research Inc. Cancerous disease modifying antibodies
US20060140963A1 (en) * 2003-04-14 2006-06-29 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of CD59
US20080025977A1 (en) * 2003-04-14 2008-01-31 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of CD59
US20050027106A1 (en) * 2003-07-28 2005-02-03 Young David S. F. Cancerous disease modifying antibodies
CA2544946A1 (en) 2003-11-24 2005-03-06 Sidney Kimmel Cancer Center Mucin antigen vaccine
US8828957B2 (en) * 2003-12-11 2014-09-09 Microvax, Llc Methods for generating immunity to antigen
US7348413B2 (en) * 2004-02-26 2008-03-25 Arius Research Inc. Cancerous disease modifying antibodies
US20050255041A1 (en) * 2004-05-13 2005-11-17 Arius Research, Inc. Cancerous disease modifying antibodies
CA2521973C (en) * 2004-09-29 2013-12-10 Tir Systems Ltd. System and method for controlling luminaires
WO2006130525A2 (en) * 2005-05-31 2006-12-07 Sidney Kimmel Cancer Center Methods for immunotherapy of cancer
US7494648B2 (en) * 2005-08-02 2009-02-24 Hoffmann-La Roche Inc. Cancerous disease modifying antibodies
US7456258B2 (en) 2005-08-02 2008-11-25 Arius Research, Inc. Cancerous disease modifying antibodies
US7411046B2 (en) 2005-08-02 2008-08-12 Arius Research Inc Cancerous disease modifying antibodies
US7452978B2 (en) * 2005-08-02 2008-11-18 Arius Research, Inc. Cancerous disease modifying antibodies
US7456259B2 (en) 2005-08-02 2008-11-25 Arius Research, Inc. Cancerous disease modifying antibodies
US7452979B2 (en) 2005-08-02 2008-11-18 Arius Research, Inc. Cancerous disease modifying antibodies
WO2007056266A2 (en) * 2005-11-07 2007-05-18 Sidney Kimmel Cancer Center Cd40 ligand fusion protein vaccine
CN101490247A (zh) 2006-02-24 2009-07-22 阿里乌斯研究公司 癌性疾病调节抗体141205-02
US7456016B2 (en) * 2006-02-24 2008-11-25 Arius Research Inc. Cancerous disease modifying antibodies
US20080305104A1 (en) * 2006-02-24 2008-12-11 Young David S F Cytotoxicity mediation of cells evidencing surface expression of TROP-2
US20080213267A1 (en) * 2006-02-24 2008-09-04 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of TROP-2
US7420040B2 (en) * 2006-02-24 2008-09-02 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of TROP-2
US20080089891A1 (en) * 2006-07-26 2008-04-17 Arius Research, Inc. Cancerous disease modifying antibodies
KR20090059166A (ko) * 2006-09-28 2009-06-10 센토코 오르토 바이오테크 인코포레이티드 단일클론 항체 생산에서 애주번트로서의 프로스타글란딘 e2 (pge2)
AU2007321665A1 (en) * 2006-11-13 2008-05-22 F. Hoffmann-La Roche Ag Cancerous disease modifying antibodies
US20080241062A1 (en) * 2006-11-13 2008-10-02 Young David S F Cancerous disease modifying antibodies
US8129502B2 (en) * 2006-11-13 2012-03-06 Hoffmann-La Roche Inc. Cancerous disease modifying antibodies
US8003761B2 (en) * 2007-01-23 2011-08-23 Hoffmann-La Roche Inc. Cancerous disease modifying antibodies
US20080206133A1 (en) * 2007-01-23 2008-08-28 Young David S F Cancerous Disease Modifying Antibodies
WO2008116299A1 (en) * 2007-03-26 2008-10-02 F. Hoffmann-La Roche Ag Cancer disease modifying antibody 010207-01 produced by hybridoma cell line ar51a630.3.
WO2008134876A1 (en) * 2007-05-07 2008-11-13 F. Hoffmann-La Roche Ag Cancerous disease modifying antibodies
US20090191197A1 (en) * 2008-01-28 2009-07-30 Young David S F Cancerous disease modifying antibodies
US20090285751A1 (en) * 2008-04-10 2009-11-19 Young David S F Cancerous disease modifying antibodies
US20090304578A1 (en) * 2008-05-19 2009-12-10 Young David S F Cancerous Disease Modifying Antibodies
WO2010007000A1 (en) * 2008-07-17 2010-01-21 F. Hoffmann-La Roche Ag Cancerous disease modifying antibodies
WO2011004899A1 (en) 2009-07-06 2011-01-13 Takeda Pharmaceutical Company Limited Cancerous disease modifying antibodies
US10035859B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
US10035860B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
WO2017117500A1 (en) 2015-12-30 2017-07-06 Colgate-Palmolive Company Mucin coated silica for bacterial aggregation
CN110317273A (zh) * 2018-03-30 2019-10-11 积水医疗株式会社 与dupan-2抗原特异性反应的单克隆抗体及其制造方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650756A (en) * 1981-08-31 1987-03-17 Sloan Kettering Institute For Cancer Research Monoclonal antibodies to cell surface antigens of human renal cancer
US4584268A (en) * 1981-10-13 1986-04-22 Ceriani Roberto Luis Method and compositions for carcinoma diagnosis
US4612282A (en) * 1981-12-15 1986-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Monoclonal antibodies reactive with human breast cancer
US4522918A (en) * 1981-12-15 1985-06-11 Jeffery Schlom Process for producing monoclonal antibodies reactive with human breast cancer
US4485093A (en) * 1982-08-13 1984-11-27 Runge Richard G Immunotoxin conjugate which comprises arsanilic acid, useful for treating malignant tumors, particularly pancreatic cancer
GB2131830A (en) * 1982-12-10 1984-06-27 Ludwig Inst Cancer Res Monoclonal antibody for use against breast cancer
US4678747A (en) * 1983-02-18 1987-07-07 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies for detection of an H (O) blood group antigen
US4916213A (en) * 1983-02-22 1990-04-10 Xoma Corporation Ribosomal inhibiting protein-immunoglobulin conjugates with specificity for tumor cell surface antigens, and mixtures thereof
CA1215331A (en) * 1983-03-04 1986-12-16 Tsann M. Chu Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy
US4643971A (en) * 1983-03-11 1987-02-17 Sloan-Kettering Institute Monoclonal antibodies to human bladder and ureter cancers and method
WO1985002411A1 (en) * 1983-11-25 1985-06-06 The University Of Melbourne Cell line and monoclonal antibody
US4753894A (en) * 1984-02-08 1988-06-28 Cetus Corporation Monoclonal anti-human breast cancer antibodies
US4935344A (en) * 1984-04-30 1990-06-19 Sloan-Kettering Institute For Cancer Research Method for characterizing types of renal carcinoma and prognosis
DE3586216T2 (de) * 1984-05-01 1992-12-10 Ciba Corning Diagnostics Corp Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
US4960716A (en) * 1984-05-01 1990-10-02 Ciba Corning Diagnostics Corp. Monoclonal antibodies specific for 330 KD breast tumor antigen and assay using said monoclonal antibodies
US4683200A (en) * 1984-05-17 1987-07-28 Setsuo Hirohashi Monoclonal antibody to human cancer antigen and method for producing same
US4752569A (en) * 1984-06-21 1988-06-21 The Regents Of The University Of California Sialylated Lewisx epitope, antibodies and diagnosis
NZ212419A (en) * 1984-06-25 1988-08-30 Mucan Diagnostics Pty Ltd In vitro diagnostic test for detecting cancer cells producing mucin antigens
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies
CA1306428C (en) * 1984-12-05 1992-08-18 Christine A. White Monoclonal antibody specific for a mammary tumor cell surface antigen
US4628032A (en) * 1984-12-05 1986-12-09 The Salk Institute For Biological Studies Monoclonal antibody specific for a mammary tumor cytoplasmic antigen
ES8800604A1 (es) * 1985-04-22 1987-11-16 Hybritech Inc Un metodo para producir anticuerpos monoclonales
US4814275A (en) * 1985-05-13 1989-03-21 E.I. Dupont De Nemours And Company Monoclonal hybridoma antibody specific for a human epithelial antigen
US4863854A (en) * 1985-08-12 1989-09-05 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to mucin-like human differentiation antigens
US4938948A (en) * 1985-10-07 1990-07-03 Cetus Corporation Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies
US4803169A (en) * 1986-02-05 1989-02-07 Cetus Corporation Assay for human breast cancer
EP1103623A1 (en) 1987-01-07 2001-05-30 Imperial Cancer Research Technology Limited Human mucin core protein: nucleic acid probes, peptide fragments and antibodies thereto, and uses thereof in diagnostic and therapeutic methods

Also Published As

Publication number Publication date
ES2080717T3 (es) 1996-02-16
KR900007951B1 (ko) 1990-10-23
IL84475A (en) 1992-06-21
KR880006358A (ko) 1988-07-22
NO874796L (no) 1988-05-20
JP2597372B2 (ja) 1997-04-02
IL84475A0 (en) 1988-04-29
DK606287A (da) 1988-05-20
DE3751585T2 (de) 1996-04-25
GR3018093T3 (en) 1996-02-29
ES2080717T5 (es) 2004-07-16
ATE130029T1 (de) 1995-11-15
DK606287D0 (da) 1987-11-18
NO175944C (no) 1995-01-04
PT86180A (en) 1987-12-01
EP0268279A3 (en) 1991-07-03
AU613590B2 (en) 1991-08-08
IE873110L (en) 1988-05-19
AU8099487A (en) 1988-06-09
HK1007766A1 (en) 1999-04-23
EP0268279B2 (en) 2003-12-03
NO175944B (no) 1994-09-26
CA1340815C (en) 1999-11-09
IE71154B1 (en) 1997-01-29
EP0268279B1 (en) 1995-11-08
DE3751585T3 (de) 2004-08-05
DE3751585D1 (de) 1995-12-14
NZ222509A (en) 1993-03-26
JPS63279784A (ja) 1988-11-16
PT86180B (pt) 1990-11-07
EP0268279A2 (en) 1988-05-25
US5849876A (en) 1998-12-15
NO874796D0 (no) 1987-11-18

Similar Documents

Publication Publication Date Title
DK175635B1 (da) Hybridomacellelinier, der producerer monoklonale antistoffer, som reagerer med nye mucinepitoper
JP4122050B2 (ja) ヒト癌腫抗原(hca)、hca抗体、hca免疫アッセイ法、画像化の方法及び治療
Kuroki et al. Serological mapping of the TAG-72 tumor-associated antigen using 19 distinct monoclonal antibodies
Linsley et al. Monoclonal antibodies reactive with mucin glycoproteins found in sera from breast cancer patients
AU606605B2 (en) Monoclonal antibodies to unreduced, nonenzymatically- glycated proteins
WO1991006865A1 (en) Human tumor-associated thomsen-friedenreich antigen
Lan et al. Polypeptide core of a human pancreatic tumor mucin antigen
JPS6319561A (ja) 抗ヒト肺癌単クロ−ン性抗体
KR910000903B1 (ko) 인체의 비-소 세포 폐암치료용 단클론의 항체 및 항원
JP3137976B2 (ja) 結腸癌のムチンエピトープに対するモノクローナル抗体を産生するハイブリドーマct43
US6004761A (en) Method for detecting cancer using monoclonal antibodies to new mucin epitopes
AU601379B2 (en) Antigen indicative of human breast cancer and assays based thereon
JPS6321562A (ja) 抗ヒト胃癌単クロ−ン性抗体amc−462
EP0184906A1 (en) Monoclonal antibodies specific for human squamous lung carninoma cells, their preparation and use
Hertzog et al. Aberrant expression of intestinal mucin antigens associated with colorectal carcinoma defined by a panel of monoclonal antibodies
JP3581160B2 (ja) 抗粘液糖タンパク質モノクローナル抗体
Deutsch et al. Detection of a novel marker in the bronchial secretions of patients with non‐small cell lung cancer using the 4B5 monoclonal antibody
Prat et al. Biochemical and immunological properties of the human carcinoma antigen car‐5 defined by the monoclonal antibody BD‐5
JP2003344414A (ja) Rcas1の測定方法、及びrcas1測定用キット
Deutsch et al. Detection of a Novel Marker in the Bronchial Secretions of Patients With Non-Small Cell Lung Cancer Using the 4B5 Monoclonal Antibody zyxwvutsrqpo
LINSLEY et al. JOSEPH P. BROWN
JPS62207298A (ja) 抗ヒト胃癌単クロ−ン性抗体
JPH06102038B2 (ja) モノクロ−ナル抗体
JPH11116500A (ja) 抗体及び診断方法
JPH0423997A (ja) モノクローナル抗体

Legal Events

Date Code Title Description
PUP Patent expired