DK175569B1 - Rekombinant DNA-molekyle, fremgangsmåde til fremstilling deraf, transformeret vært indeholdende det rekombinante DNA-molekyle, fremgangsmåde til fremstilling af den transformerede vært samt fremgangsmåde til fremstilling af et polypeptid - Google Patents

Rekombinant DNA-molekyle, fremgangsmåde til fremstilling deraf, transformeret vært indeholdende det rekombinante DNA-molekyle, fremgangsmåde til fremstilling af den transformerede vært samt fremgangsmåde til fremstilling af et polypeptid Download PDF

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DK175569B1
DK175569B1 DK198800545A DK54588A DK175569B1 DK 175569 B1 DK175569 B1 DK 175569B1 DK 198800545 A DK198800545 A DK 198800545A DK 54588 A DK54588 A DK 54588A DK 175569 B1 DK175569 B1 DK 175569B1
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dna
recombinant dna
dna molecule
pli
gene
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DK198800545A
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Danish (da)
English (en)
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DK54588A (da
DK54588D0 (da
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Jutta Heim
Jacob Visser
Christof Gysler
Hermanus Cornelius Mari Kester
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Novartis Ag
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/685—Aspergillus niger

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Image Generation (AREA)
  • Complex Calculations (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Multi-Process Working Machines And Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hardware Redundancy (AREA)
DK198800545A 1987-02-04 1988-02-03 Rekombinant DNA-molekyle, fremgangsmåde til fremstilling deraf, transformeret vært indeholdende det rekombinante DNA-molekyle, fremgangsmåde til fremstilling af den transformerede vært samt fremgangsmåde til fremstilling af et polypeptid DK175569B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878702475A GB8702475D0 (en) 1987-02-04 1987-02-04 Expression system
GB8702475 1987-02-04

Publications (3)

Publication Number Publication Date
DK54588D0 DK54588D0 (da) 1988-02-03
DK54588A DK54588A (da) 1988-08-05
DK175569B1 true DK175569B1 (da) 2004-12-13

Family

ID=10611694

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198800545A DK175569B1 (da) 1987-02-04 1988-02-03 Rekombinant DNA-molekyle, fremgangsmåde til fremstilling deraf, transformeret vært indeholdende det rekombinante DNA-molekyle, fremgangsmåde til fremstilling af den transformerede vært samt fremgangsmåde til fremstilling af et polypeptid

Country Status (23)

Country Link
EP (2) EP0278355B2 (fr)
JP (1) JP2633885B2 (fr)
KR (1) KR970001116B1 (fr)
AT (1) ATE133706T1 (fr)
AU (1) AU625773B2 (fr)
CA (1) CA1327330C (fr)
DD (3) DD267511A5 (fr)
DE (1) DE3854947T3 (fr)
DK (1) DK175569B1 (fr)
ES (1) ES2082746T5 (fr)
FI (1) FI105484B (fr)
GB (1) GB8702475D0 (fr)
GR (1) GR3018863T3 (fr)
HU (1) HU214005B (fr)
IE (2) IE960902L (fr)
IL (1) IL85293A (fr)
MX (1) MX10286A (fr)
NO (1) NO179078C (fr)
NZ (1) NZ223392A (fr)
PH (1) PH26106A (fr)
PT (1) PT86684B (fr)
YU (1) YU21688A (fr)
ZA (1) ZA88757B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5576195A (en) * 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
EP0396612B1 (fr) * 1988-01-11 1996-07-24 Xoma Corporation Nouveau vecteur de plasmide avec sequence a fonction de signal pour pectate lyase
AU627443B2 (en) * 1988-01-11 1992-08-27 Xoma Corporation Novel plasmid vector with pectate lyase signal sequence
ES2063162T5 (es) * 1988-07-28 2002-11-16 Novartis Ag Nuevo sistema de expresion.
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
PL175670B1 (pl) * 1992-12-24 1999-01-29 Gist Brocades Nv Oczyszczona i wyizolowana sekwencja DNA kodująca polipeptyd wykazujący aktywność enzymu poligalakturonazy (PGX) z Aspergillus tubigensis
AU677296B2 (en) * 1993-02-16 1997-04-17 Novozymes A/S An enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
WO1997038123A1 (fr) * 1996-04-05 1997-10-16 Board Of Regents, The University Of Texas System Procedes de production de proteines eucaryotes, solubles, actives sur plan biologique et contenant des liaisons disulfure, a l'interieur de cellules bacteriennes
US6083715A (en) * 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
US6165769A (en) * 1997-11-24 2000-12-26 Novo Nordisk A/S Pectin degrading enzymes from Bacillus licheniformis
WO1999027083A1 (fr) * 1997-11-24 1999-06-03 Novo Nordisk A/S ENZYMES DE DEGRADATION DE LA PECTINE PROVENANT DU $i(BACILLUS LICHENIFORMIS)
US6187580B1 (en) 1997-11-24 2001-02-13 Novo Nordisk A/S Pectate lyases
EP1187925B1 (fr) * 1999-06-02 2005-03-30 Novozymes A/S Fusion de lyase de pectate permettant d'exprimer et de secreter des polypeptides
EP2379717B1 (fr) 2008-12-19 2015-09-02 DuPont Nutrition Biosciences ApS Complexe d'enzyme
TR201809053T4 (tr) 2012-08-16 2018-07-23 Bangladesh Jute Res Institute Macrophomina phaseolina'dan elde edilen pektin parçalama enzimleri ve bunların kullanımları.
WO2023225459A2 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885249A (en) 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
AU606033B2 (en) 1985-04-15 1991-01-31 Dsm Ip Assets B.V. Promotors of filamentous fungi and use thereof
ES2063162T5 (es) * 1988-07-28 2002-11-16 Novartis Ag Nuevo sistema de expresion.

Also Published As

Publication number Publication date
ZA88757B (en) 1988-08-04
IE880292L (en) 1988-08-04
GB8702475D0 (en) 1987-03-11
FI105484B (fi) 2000-08-31
ES2082746T5 (es) 2003-06-16
PT86684A (pt) 1988-03-01
MX10286A (es) 1993-12-01
CA1327330C (fr) 1994-03-01
NO179078B (no) 1996-04-22
EP0278355B2 (fr) 2002-10-23
PH26106A (en) 1992-02-06
DE3854947T3 (de) 2003-04-30
NO880470L (no) 1988-08-05
DK54588A (da) 1988-08-05
PT86684B (pt) 1992-04-30
KR970001116B1 (en) 1997-01-28
DE3854947T2 (de) 1996-11-14
DK54588D0 (da) 1988-02-03
IL85293A (en) 1992-12-01
JPS63273480A (ja) 1988-11-10
FI880439A (fi) 1988-08-05
KR880010126A (ko) 1988-10-07
GR3018863T3 (en) 1996-05-31
HU214005B (hu) 1998-08-28
JP2633885B2 (ja) 1997-07-23
DE3854947D1 (de) 1996-03-14
ES2082746T3 (es) 1996-04-01
NO880470D0 (no) 1988-02-03
DD283838A5 (de) 1990-10-24
AU625773B2 (en) 1992-07-16
EP0683228A2 (fr) 1995-11-22
IL85293A0 (en) 1988-07-31
HUT46357A (en) 1988-10-28
AU1123488A (en) 1988-08-18
DD283837A5 (de) 1990-10-24
EP0278355A2 (fr) 1988-08-17
IE960902L (en) 1988-08-04
FI880439A0 (fi) 1988-02-01
DD267511A5 (de) 1989-05-03
EP0278355A3 (en) 1989-12-20
EP0683228A3 (fr) 1996-03-06
NZ223392A (en) 1991-05-28
NO179078C (no) 1996-07-31
EP0278355B1 (fr) 1996-01-31
ATE133706T1 (de) 1996-02-15
IE72506B1 (en) 1997-04-23
YU21688A (en) 1991-04-30

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