DK175252B1 - Implanterbart biologisk nedbrydeligt system til frigivelse af biologisk virksomme stoffer - Google Patents
Implanterbart biologisk nedbrydeligt system til frigivelse af biologisk virksomme stoffer Download PDFInfo
- Publication number
- DK175252B1 DK175252B1 DK198805615A DK561588A DK175252B1 DK 175252 B1 DK175252 B1 DK 175252B1 DK 198805615 A DK198805615 A DK 198805615A DK 561588 A DK561588 A DK 561588A DK 175252 B1 DK175252 B1 DK 175252B1
- Authority
- DK
- Denmark
- Prior art keywords
- release
- active
- film
- active substance
- small
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3734223 | 1987-10-09 | ||
DE19873734223 DE3734223A1 (de) | 1987-10-09 | 1987-10-09 | Implantierbares, biologisch abbaubares wirkstofffreigabesystem |
Publications (3)
Publication Number | Publication Date |
---|---|
DK561588D0 DK561588D0 (da) | 1988-10-07 |
DK561588A DK561588A (da) | 1989-04-10 |
DK175252B1 true DK175252B1 (da) | 2004-07-19 |
Family
ID=6338006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198805615A DK175252B1 (da) | 1987-10-09 | 1988-10-07 | Implanterbart biologisk nedbrydeligt system til frigivelse af biologisk virksomme stoffer |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0311065B1 (fr) |
JP (1) | JP2763303B2 (fr) |
KR (1) | KR970006082B1 (fr) |
AT (1) | ATE101035T1 (fr) |
AU (1) | AU609194B2 (fr) |
CA (1) | CA1333770C (fr) |
DE (2) | DE3734223A1 (fr) |
DK (1) | DK175252B1 (fr) |
ES (1) | ES2061589T3 (fr) |
FI (1) | FI100302B (fr) |
IE (1) | IE62505B1 (fr) |
IL (1) | IL87973A (fr) |
NO (1) | NO176304C (fr) |
NZ (1) | NZ226514A (fr) |
PH (1) | PH30236A (fr) |
PT (1) | PT88703B (fr) |
ZA (1) | ZA887535B (fr) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2209937B (en) * | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
US5216050A (en) * | 1988-08-08 | 1993-06-01 | Biopak Technology, Ltd. | Blends of polyactic acid |
US5180765A (en) * | 1988-08-08 | 1993-01-19 | Biopak Technology, Ltd. | Biodegradable packaging thermoplastics from lactides |
US5424346A (en) * | 1988-08-08 | 1995-06-13 | Ecopol, Llc | Biodegradable replacement of crystal polystyrene |
US5444113A (en) * | 1988-08-08 | 1995-08-22 | Ecopol, Llc | End use applications of biodegradable polymers |
US6323307B1 (en) | 1988-08-08 | 2001-11-27 | Cargill Dow Polymers, Llc | Degradation control of environmentally degradable disposable materials |
US5252642A (en) * | 1989-03-01 | 1993-10-12 | Biopak Technology, Ltd. | Degradable impact modified polyactic acid |
US5702716A (en) * | 1988-10-03 | 1997-12-30 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
CA2056384C (fr) * | 1989-06-05 | 1998-06-23 | Tobin N. Gerhart | Polymeres bioerodables pour la liberation de medicaments dans les os |
US5487897A (en) * | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
US5439688A (en) * | 1989-07-28 | 1995-08-08 | Debio Recherche Pharmaceutique S.A. | Process for preparing a pharmaceutical composition |
CH679207A5 (fr) * | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
DE69101313T2 (de) * | 1990-01-30 | 1994-06-30 | Akzo Nv | Gegenstand zur gesteuerten wirkstoffabgabe mit einem von einer wand völlig umschlossenen hohlraum und völlig oder teilweise mit einem oder mehreren wirkstoffen gefüllt. |
DE69004415D1 (de) * | 1990-03-05 | 1993-12-09 | Minnesota Mining & Mfg | Vorrichtung zur verzögerten Abgabe von pharmakologisch aktiven Verbindungen ins Ohr. |
US5350580A (en) * | 1990-03-05 | 1994-09-27 | Minnesota Mining And Manufacturing Company | Device and method for extended delivery of pharmacologically active agents to the ear |
AU2605592A (en) * | 1991-10-15 | 1993-04-22 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
US5681873A (en) * | 1993-10-14 | 1997-10-28 | Atrix Laboratories, Inc. | Biodegradable polymeric composition |
US5605696A (en) * | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
US5869079A (en) | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
AU6491898A (en) * | 1997-04-04 | 1998-10-30 | Alcan International Limited | Aluminum alloy composition and method of manufacture |
MY118835A (en) * | 1997-04-18 | 2005-01-31 | Ipsen Pharma Biotech | Sustained release compositions and the process for their preparation |
US6261583B1 (en) | 1998-07-28 | 2001-07-17 | Atrix Laboratories, Inc. | Moldable solid delivery system |
US6143314A (en) * | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
DE19908753C2 (de) * | 1999-02-20 | 2003-10-02 | Jenapharm Gmbh | Bioabbaubare, injizierbare Oligomer-Polymer-Zusammensetzung |
US6306425B1 (en) * | 1999-04-09 | 2001-10-23 | Southern Research Institute | Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol |
US8226598B2 (en) | 1999-09-24 | 2012-07-24 | Tolmar Therapeutics, Inc. | Coupling syringe system and methods for obtaining a mixed composition |
US6702849B1 (en) | 1999-12-13 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers |
DE60132525T2 (de) | 2000-03-22 | 2009-01-29 | Dainippon Ink And Chemicals, Inc. | Schlagzäh-modifizierer und diese modifizierer enthaltende polyesterzusammensetzung |
US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
EP3167872B1 (fr) * | 2000-07-05 | 2020-10-14 | Allergan, Inc. | Procédés de traitement des états inflammatoires de l' oeil |
AU3649502A (en) | 2000-11-29 | 2002-06-11 | Oculex Pharm Inc | Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
US20050048099A1 (en) | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
US20070224278A1 (en) | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
CA2553381C (fr) | 2004-01-20 | 2011-03-22 | Allergan, Inc. | Compositions pour traitement local de l'oeil, comprenant de preference de l'acetonide de triamcinolone et de l'acide hyaluronique |
US8591885B2 (en) | 2004-04-30 | 2013-11-26 | Allergan, Inc. | Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems |
US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
BRPI0510485A (pt) | 2004-04-30 | 2007-11-13 | Allergan Inc | implantes inibidores de tirosina cinase intravìtreos biodegradáveis |
US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
US20050244463A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular vasculopathies |
US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
US8147865B2 (en) | 2004-04-30 | 2012-04-03 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US20050244458A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
US7771742B2 (en) | 2004-04-30 | 2010-08-10 | Allergan, Inc. | Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods |
US8475829B2 (en) * | 2006-04-06 | 2013-07-02 | Nupathe Inc. | Implants for the treatment of dopamine associated states |
US8802128B2 (en) | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
US8889173B2 (en) * | 2008-04-18 | 2014-11-18 | Warsaw Orthopedic, Inc. | Alpha adrenergic receptor agonists for treatment of pain and/or inflammation |
US8956641B2 (en) * | 2008-04-18 | 2015-02-17 | Warsaw Orthopedic, Inc. | Alpha adrenergic receptor agonists for treatment of inflammatory diseases |
US10588855B2 (en) | 2008-05-12 | 2020-03-17 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
JP5982287B2 (ja) | 2009-11-09 | 2016-08-31 | アラーガン、インコーポレイテッドAllergan,Incorporated | 発毛を刺激する組成物および方法 |
JP4779169B1 (ja) * | 2010-10-27 | 2011-09-28 | Necインフロンティア株式会社 | ボタン照明構造、電子機器 |
RU2641021C2 (ru) | 2013-02-15 | 2018-01-17 | Аллерган, Инк. | Имплантат для пролонгированной доставки лекарственного средства |
GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
CA3078555A1 (fr) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | Depots implantabes pour la liberation controlee d'agents therapeutiques |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL109293C (fr) * | 1955-12-22 | |||
US3755558A (en) * | 1971-02-23 | 1973-08-28 | Du Pont | Polylactide drug mixtures for topical application atelet aggregation |
DE3218150C2 (de) * | 1982-05-14 | 1986-09-25 | Akzo Gmbh, 5600 Wuppertal | Wirkstoff enthaltender Körper für die Langzeitabgabe sowie Verfahren zu dessen Herstellung |
US4962091A (en) * | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
US4758435A (en) * | 1986-08-11 | 1988-07-19 | American Cyanamid Company | Estradiol implant composition and method for preparation |
DE3710175A1 (de) * | 1987-02-12 | 1988-08-25 | Hoechst Ag | Mehrteilige implantierbare arzneizubereitung mit langzeitwirkung |
-
1987
- 1987-10-09 DE DE19873734223 patent/DE3734223A1/de not_active Withdrawn
-
1988
- 1988-10-06 DE DE88116522T patent/DE3887616D1/de not_active Expired - Lifetime
- 1988-10-06 AT AT88116522T patent/ATE101035T1/de not_active IP Right Cessation
- 1988-10-06 ES ES88116522T patent/ES2061589T3/es not_active Expired - Lifetime
- 1988-10-06 EP EP88116522A patent/EP0311065B1/fr not_active Expired - Lifetime
- 1988-10-07 NO NO884474A patent/NO176304C/no not_active IP Right Cessation
- 1988-10-07 FI FI884604A patent/FI100302B/fi not_active IP Right Cessation
- 1988-10-07 IL IL87973A patent/IL87973A/xx active Protection Beyond IP Right Term
- 1988-10-07 IE IE304088A patent/IE62505B1/en not_active IP Right Cessation
- 1988-10-07 AU AU23522/88A patent/AU609194B2/en not_active Expired
- 1988-10-07 CA CA000579561A patent/CA1333770C/fr not_active Expired - Lifetime
- 1988-10-07 DK DK198805615A patent/DK175252B1/da active
- 1988-10-07 JP JP63253600A patent/JP2763303B2/ja not_active Expired - Lifetime
- 1988-10-07 PT PT88703A patent/PT88703B/pt not_active IP Right Cessation
- 1988-10-07 PH PH37650A patent/PH30236A/en unknown
- 1988-10-07 ZA ZA887535A patent/ZA887535B/xx unknown
- 1988-10-08 KR KR1019880013156A patent/KR970006082B1/ko not_active IP Right Cessation
- 1988-10-10 NZ NZ226514A patent/NZ226514A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PH30236A (en) | 1997-02-05 |
IL87973A (en) | 1992-08-18 |
EP0311065B1 (fr) | 1994-02-02 |
KR890006222A (ko) | 1989-06-12 |
PT88703B (pt) | 1992-12-31 |
DK561588D0 (da) | 1988-10-07 |
EP0311065A1 (fr) | 1989-04-12 |
DE3734223A1 (de) | 1989-04-20 |
NO884474D0 (no) | 1988-10-07 |
FI884604A0 (fi) | 1988-10-07 |
DE3887616D1 (de) | 1994-03-17 |
DK561588A (da) | 1989-04-10 |
FI884604A (fi) | 1989-04-10 |
NO884474L (no) | 1989-04-10 |
IE883040L (en) | 1989-04-09 |
NO176304C (no) | 1995-03-22 |
CA1333770C (fr) | 1995-01-03 |
NZ226514A (en) | 1990-02-26 |
AU609194B2 (en) | 1991-04-26 |
JP2763303B2 (ja) | 1998-06-11 |
IE62505B1 (en) | 1995-02-08 |
PT88703A (pt) | 1988-11-01 |
ES2061589T3 (es) | 1994-12-16 |
JPH02117A (ja) | 1990-01-05 |
FI100302B (fi) | 1997-11-14 |
ZA887535B (en) | 1990-06-27 |
AU2352288A (en) | 1989-04-13 |
IL87973A0 (en) | 1989-03-31 |
KR970006082B1 (ko) | 1997-04-23 |
NO176304B (no) | 1994-12-05 |
ATE101035T1 (de) | 1994-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK175252B1 (da) | Implanterbart biologisk nedbrydeligt system til frigivelse af biologisk virksomme stoffer | |
US5633002A (en) | Implantable, biodegradable system for releasing active substance | |
KR102637575B1 (ko) | 버스트 방출이 감소된 약물 전달용 이식 가능한 장치 | |
KR101194894B1 (ko) | 클로니딘을 포함하는 수술-후 통증 치료용 조성물 | |
JP5881606B2 (ja) | 脊髄損傷治療用製剤 | |
US6206920B1 (en) | Composition and method for forming biodegradable implants in situ and uses of these implants | |
JP2003517014A (ja) | 即放性および徐放性成分を含有する医薬インプラントおよび投与方法 | |
JP2009539862A (ja) | 強化剤を含む固体経口投与剤形 | |
JP2009268915A (ja) | ゼロ次長期放出同軸インプラント | |
KR19990022212A (ko) | 친수성 제제와 소수성 제제를 혼합하여 약물 방출을 조절하는개선된 제형 | |
BG64782B1 (bg) | Течни полимерни състави за контролирано отделяне на биоактивни вещества, метод за получаването и използването им | |
MXPA05013698A (es) | Implantes subcutaneos con liberacion inicial limitada del principio activo y subsiguiente liberacion extendida linear variante del mismo. | |
JP2005521682A (ja) | 結腸放出組成物 | |
CN112601519A (zh) | 用作植入物的可负载多孔结构 | |
JP6250005B2 (ja) | 制御放出製剤 | |
US20060099254A1 (en) | Sustained release drug delivery system and method | |
JPH029812A (ja) | 活性物質の制御放出用経口投与系 | |
US20210113664A1 (en) | Implants for release of lipophilic or amphiphilic pharmaceutical substances | |
JP2007130028A (ja) | 薬剤塗付医療用具 | |
JP2018500278A (ja) | 外部粘膜に適用する剤形物品 | |
CN107205942A (zh) | 包含富马酸二甲酯的药物基质制剂 | |
JP5898619B2 (ja) | 水溶性薬物放出制御製剤 | |
WO2023086832A1 (fr) | Procédés de préparation de formes posologiques à l'aide d'une impression 3d contenant des dispersions solides amorphes | |
McConville | Ian Major1, Sarah Lastakchi2, Maurice Dalton1 and | |
WO2022175977A1 (fr) | Composition d'implant biodégradable et procédé d'administration à long terme de buprénorphine et utilisation associée |