PH30236A - Implantable biodegradable system for releasing active substance - Google Patents
Implantable biodegradable system for releasing active substanceInfo
- Publication number
- PH30236A PH30236A PH37650A PH37650A PH30236A PH 30236 A PH30236 A PH 30236A PH 37650 A PH37650 A PH 37650A PH 37650 A PH37650 A PH 37650A PH 30236 A PH30236 A PH 30236A
- Authority
- PH
- Philippines
- Prior art keywords
- active substance
- releasing active
- implantable biodegradable
- biodegradable system
- carrier material
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
Abstract
The system consists of a carrier material based on poly-D,L-lactide and of a drug incorporated therein and, where appropriate pharmaceutical auxiliaries. The carrier material contains defined contents of additives in the form of pore formers, up to about 10% by weight of a physiologically acceptable solvent or plasticiser and/or low molecular weight polymers.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873734223 DE3734223A1 (en) | 1987-10-09 | 1987-10-09 | IMPLANTABLE, BIODEGRADABLE ACTIVE SUBSTANCE RELEASE SYSTEM |
Publications (1)
Publication Number | Publication Date |
---|---|
PH30236A true PH30236A (en) | 1997-02-05 |
Family
ID=6338006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH37650A PH30236A (en) | 1987-10-09 | 1988-10-07 | Implantable biodegradable system for releasing active substance |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0311065B1 (en) |
JP (1) | JP2763303B2 (en) |
KR (1) | KR970006082B1 (en) |
AT (1) | ATE101035T1 (en) |
AU (1) | AU609194B2 (en) |
CA (1) | CA1333770C (en) |
DE (2) | DE3734223A1 (en) |
DK (1) | DK175252B1 (en) |
ES (1) | ES2061589T3 (en) |
FI (1) | FI100302B (en) |
IE (1) | IE62505B1 (en) |
IL (1) | IL87973A (en) |
NO (1) | NO176304C (en) |
NZ (1) | NZ226514A (en) |
PH (1) | PH30236A (en) |
PT (1) | PT88703B (en) |
ZA (1) | ZA887535B (en) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
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GB2209937B (en) * | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
US5216050A (en) * | 1988-08-08 | 1993-06-01 | Biopak Technology, Ltd. | Blends of polyactic acid |
US5252642A (en) * | 1989-03-01 | 1993-10-12 | Biopak Technology, Ltd. | Degradable impact modified polyactic acid |
US6323307B1 (en) | 1988-08-08 | 2001-11-27 | Cargill Dow Polymers, Llc | Degradation control of environmentally degradable disposable materials |
US5180765A (en) * | 1988-08-08 | 1993-01-19 | Biopak Technology, Ltd. | Biodegradable packaging thermoplastics from lactides |
US5424346A (en) * | 1988-08-08 | 1995-06-13 | Ecopol, Llc | Biodegradable replacement of crystal polystyrene |
US5444113A (en) * | 1988-08-08 | 1995-08-22 | Ecopol, Llc | End use applications of biodegradable polymers |
US5702716A (en) * | 1988-10-03 | 1997-12-30 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
ATE141804T1 (en) * | 1989-06-05 | 1996-09-15 | Massachusetts Inst Technology | BIODEGRADABLE POLYMERS FOR DRUG ADMINISTRATION IN BONE |
US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
US5439688A (en) * | 1989-07-28 | 1995-08-08 | Debio Recherche Pharmaceutique S.A. | Process for preparing a pharmaceutical composition |
CH679207A5 (en) * | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
EP0514406B1 (en) * | 1990-01-30 | 1994-03-02 | Akzo Nobel N.V. | Article for the controlled delivery of an active substance, comprising a hollow space fully enclosed by a wall and filled in full or in part with one or more active substances |
EP0447719B1 (en) * | 1990-03-05 | 1993-11-03 | Minnesota Mining And Manufacturing Company | Device for extended delivery of pharmacologically active agents to the ear |
US5350580A (en) * | 1990-03-05 | 1994-09-27 | Minnesota Mining And Manufacturing Company | Device and method for extended delivery of pharmacologically active agents to the ear |
AU2605592A (en) * | 1991-10-15 | 1993-04-22 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
US5681873A (en) * | 1993-10-14 | 1997-10-28 | Atrix Laboratories, Inc. | Biodegradable polymeric composition |
US5605696A (en) * | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
US6350532B1 (en) * | 1997-04-04 | 2002-02-26 | Alcan International Ltd. | Aluminum alloy composition and method of manufacture |
TW577759B (en) * | 1997-04-18 | 2004-03-01 | Ipsen Pharma Biotech | Sustained release compositions in the form of microcapsules or implants and the process for their preparation |
US6261583B1 (en) | 1998-07-28 | 2001-07-17 | Atrix Laboratories, Inc. | Moldable solid delivery system |
US6143314A (en) * | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
DE19908753C2 (en) * | 1999-02-20 | 2003-10-02 | Jenapharm Gmbh | Biodegradable, injectable oligomer-polymer composition |
US6306425B1 (en) * | 1999-04-09 | 2001-10-23 | Southern Research Institute | Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol |
US8226598B2 (en) | 1999-09-24 | 2012-07-24 | Tolmar Therapeutics, Inc. | Coupling syringe system and methods for obtaining a mixed composition |
US6702849B1 (en) | 1999-12-13 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers |
EP1188781B1 (en) | 2000-03-22 | 2008-01-23 | Dainippon Ink And Chemicals, Inc. | Impact modifier and polyester composition containing the modifier |
US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
EP3167872B1 (en) * | 2000-07-05 | 2020-10-14 | Allergan, Inc. | Methods for treating inflammation-mediated conditions of the eye |
ES2250504T3 (en) | 2000-11-29 | 2006-04-16 | Allergan Inc. | PREVENTION OF REJECTION OF GRAFT IN THE EYE. |
US20050048099A1 (en) | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
US20070224278A1 (en) | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
AU2005209201B2 (en) | 2004-01-20 | 2010-06-03 | Allergan, Inc. | Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
US7771742B2 (en) | 2004-04-30 | 2010-08-10 | Allergan, Inc. | Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods |
US8147865B2 (en) | 2004-04-30 | 2012-04-03 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
BRPI0510485A (en) | 2004-04-30 | 2007-11-13 | Allergan Inc | biodegradable intravitreal tyrosine kinase inhibitor implants |
US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
US8591885B2 (en) | 2004-04-30 | 2013-11-26 | Allergan, Inc. | Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems |
US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
US20050244463A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular vasculopathies |
US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
US20050244458A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
DK2010184T3 (en) * | 2006-04-06 | 2013-03-25 | Nupathe Inc | Implants for the treatment of dopamine associated conditions |
US8802128B2 (en) | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
US8889173B2 (en) * | 2008-04-18 | 2014-11-18 | Warsaw Orthopedic, Inc. | Alpha adrenergic receptor agonists for treatment of pain and/or inflammation |
US8956641B2 (en) * | 2008-04-18 | 2015-02-17 | Warsaw Orthopedic, Inc. | Alpha adrenergic receptor agonists for treatment of inflammatory diseases |
US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US10588855B2 (en) | 2008-05-12 | 2020-03-17 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
BR122017013201B1 (en) | 2009-11-09 | 2018-05-15 | Allergan, Inc. | COMPOSITION FOR STIMULATION OF HAIR GROWTH |
JP4779169B1 (en) * | 2010-10-27 | 2011-09-28 | Necインフロンティア株式会社 | Button lighting structure, electronic equipment |
CN109602691A (en) | 2013-02-15 | 2019-04-12 | 阿勒根公司 | Sustained drug delivery implantation material |
GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
WO2019071246A2 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | Implantable depots for controlled release of analgesics to treat postoperative pain, and associated devices, systems, and methods |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL109293C (en) * | 1955-12-22 | |||
US3755558A (en) * | 1971-02-23 | 1973-08-28 | Du Pont | Polylactide drug mixtures for topical application atelet aggregation |
DE3218150C2 (en) * | 1982-05-14 | 1986-09-25 | Akzo Gmbh, 5600 Wuppertal | Active substance-containing body for long-term release and process for its production |
US4962091A (en) * | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
US4758435A (en) * | 1986-08-11 | 1988-07-19 | American Cyanamid Company | Estradiol implant composition and method for preparation |
DE3710175A1 (en) * | 1987-02-12 | 1988-08-25 | Hoechst Ag | MULTI-PIECE IMPLANTABLE MEDICINE PREPARATION WITH LONG-TERM EFFECT |
-
1987
- 1987-10-09 DE DE19873734223 patent/DE3734223A1/en not_active Withdrawn
-
1988
- 1988-10-06 EP EP88116522A patent/EP0311065B1/en not_active Expired - Lifetime
- 1988-10-06 AT AT88116522T patent/ATE101035T1/en not_active IP Right Cessation
- 1988-10-06 ES ES88116522T patent/ES2061589T3/en not_active Expired - Lifetime
- 1988-10-06 DE DE88116522T patent/DE3887616D1/en not_active Expired - Lifetime
- 1988-10-07 AU AU23522/88A patent/AU609194B2/en not_active Expired
- 1988-10-07 ZA ZA887535A patent/ZA887535B/en unknown
- 1988-10-07 JP JP63253600A patent/JP2763303B2/en not_active Expired - Lifetime
- 1988-10-07 NO NO884474A patent/NO176304C/en not_active IP Right Cessation
- 1988-10-07 IL IL87973A patent/IL87973A/en active Protection Beyond IP Right Term
- 1988-10-07 IE IE304088A patent/IE62505B1/en not_active IP Right Cessation
- 1988-10-07 PT PT88703A patent/PT88703B/en not_active IP Right Cessation
- 1988-10-07 DK DK198805615A patent/DK175252B1/en active
- 1988-10-07 PH PH37650A patent/PH30236A/en unknown
- 1988-10-07 FI FI884604A patent/FI100302B/en not_active IP Right Cessation
- 1988-10-07 CA CA000579561A patent/CA1333770C/en not_active Expired - Lifetime
- 1988-10-08 KR KR1019880013156A patent/KR970006082B1/en not_active IP Right Cessation
- 1988-10-10 NZ NZ226514A patent/NZ226514A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL87973A (en) | 1992-08-18 |
DK561588A (en) | 1989-04-10 |
EP0311065A1 (en) | 1989-04-12 |
PT88703A (en) | 1988-11-01 |
KR890006222A (en) | 1989-06-12 |
PT88703B (en) | 1992-12-31 |
NO884474L (en) | 1989-04-10 |
FI884604A (en) | 1989-04-10 |
CA1333770C (en) | 1995-01-03 |
NZ226514A (en) | 1990-02-26 |
FI100302B (en) | 1997-11-14 |
NO176304C (en) | 1995-03-22 |
JP2763303B2 (en) | 1998-06-11 |
DK175252B1 (en) | 2004-07-19 |
IE883040L (en) | 1989-04-09 |
KR970006082B1 (en) | 1997-04-23 |
AU2352288A (en) | 1989-04-13 |
ES2061589T3 (en) | 1994-12-16 |
IE62505B1 (en) | 1995-02-08 |
ATE101035T1 (en) | 1994-02-15 |
FI884604A0 (en) | 1988-10-07 |
DK561588D0 (en) | 1988-10-07 |
DE3734223A1 (en) | 1989-04-20 |
NO884474D0 (en) | 1988-10-07 |
AU609194B2 (en) | 1991-04-26 |
ZA887535B (en) | 1990-06-27 |
IL87973A0 (en) | 1989-03-31 |
NO176304B (en) | 1994-12-05 |
EP0311065B1 (en) | 1994-02-02 |
JPH02117A (en) | 1990-01-05 |
DE3887616D1 (en) | 1994-03-17 |
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