IL85144A - Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation - Google Patents

Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation

Info

Publication number
IL85144A
IL85144A IL85144A IL8514488A IL85144A IL 85144 A IL85144 A IL 85144A IL 85144 A IL85144 A IL 85144A IL 8514488 A IL8514488 A IL 8514488A IL 85144 A IL85144 A IL 85144A
Authority
IL
Israel
Prior art keywords
polymers
carboxylic acid
acid esters
preparation
carrier
Prior art date
Application number
IL85144A
Other versions
IL85144A0 (en
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of IL85144A0 publication Critical patent/IL85144A0/en
Publication of IL85144A publication Critical patent/IL85144A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The medicinal preparation having controlled continuous release of active compound is prepared from an excipient based on biologically degradable cyclic carboxylic acid esters, oligomers derived therefrom and/or polymers.
IL85144A 1987-01-21 1988-01-20 Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation IL85144A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873701625 DE3701625A1 (en) 1987-01-21 1987-01-21 PERORAL DRUG PREPARATION WITH DELAYED ACTIVE RELEASE

Publications (2)

Publication Number Publication Date
IL85144A0 IL85144A0 (en) 1988-06-30
IL85144A true IL85144A (en) 1991-06-30

Family

ID=6319213

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85144A IL85144A (en) 1987-01-21 1988-01-20 Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation

Country Status (14)

Country Link
EP (1) EP0275961B1 (en)
JP (1) JP2744240B2 (en)
KR (1) KR970002615B1 (en)
AT (1) ATE106718T1 (en)
AU (1) AU605824B2 (en)
CA (1) CA1329767C (en)
DE (2) DE3701625A1 (en)
DK (1) DK23588A (en)
FI (1) FI93425C (en)
IL (1) IL85144A (en)
MX (1) MX10146A (en)
NO (1) NO175352C (en)
NZ (1) NZ223228A (en)
ZA (1) ZA88358B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981696A (en) * 1986-12-22 1991-01-01 E. I. Du Pont De Nemours And Company Polylactide compositions
US4902515A (en) * 1988-04-28 1990-02-20 E. I. Dupont De Nemours And Company Polylactide compositions
FR2634770B1 (en) * 1988-07-29 1990-10-05 Rhone Poulenc Chimie EODABLE POLYESTER COMPOSITION CONTAINING IODINE FOR WATER TREATMENT
DE59003337D1 (en) * 1989-10-16 1993-12-09 Danubia Petrochem Polymere Pressling with delayed release of active ingredient.
DE4041563A1 (en) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS
DE19500977C2 (en) * 1995-01-14 1999-01-07 Lohmann Therapie Syst Lts Solid drug form with active ingredient distributed in polymeric material
DE19908753C2 (en) 1999-02-20 2003-10-02 Jenapharm Gmbh Biodegradable, injectable oligomer-polymer composition
EP3148552B1 (en) 2014-05-30 2019-07-31 Translate Bio, Inc. Biodegradable lipids for delivery of nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CA1098443A (en) * 1977-05-20 1981-03-31 Namassivaya Doddi Absorbable p-dioxanone polymer-drug compositions
DE2824112A1 (en) * 1978-06-01 1979-12-06 Garching Instrumente Micro-pellets of biodegradable polymeric carrier - esp. poly:hydroxy-carboxylic acid, and active ingredient e.g. narcotic antagonist
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS5966425A (en) * 1982-10-08 1984-04-14 Mitsui Toatsu Chem Inc Preparation of fine particle using biodegradable polymer
FR2557459B1 (en) * 1984-01-02 1986-05-30 Lhd Lab Hygiene Dietetique POLYCAPROLACTONE-BASED INERT MATRIX FOR ORAL ADMINISTRATION OF A MEDICAMENT, AND METHOD FOR PREPARING THE GALENIC FORM COMPRISING THE SAME

Also Published As

Publication number Publication date
EP0275961A2 (en) 1988-07-27
IL85144A0 (en) 1988-06-30
FI880210A (en) 1988-07-22
JPS6419025A (en) 1989-01-23
NO175352B (en) 1994-06-27
EP0275961B1 (en) 1994-06-08
FI880210A0 (en) 1988-01-19
MX10146A (en) 1993-09-01
CA1329767C (en) 1994-05-24
DK23588A (en) 1988-07-22
ZA88358B (en) 1989-09-27
NO880230L (en) 1988-07-22
DE3889933D1 (en) 1994-07-14
DE3701625A1 (en) 1988-08-04
EP0275961A3 (en) 1990-11-22
ATE106718T1 (en) 1994-06-15
NO175352C (en) 1994-10-05
KR970002615B1 (en) 1997-03-06
AU1065388A (en) 1988-07-28
NO880230D0 (en) 1988-01-20
JP2744240B2 (en) 1998-04-28
KR880008806A (en) 1988-09-13
NZ223228A (en) 1990-12-21
AU605824B2 (en) 1991-01-24
FI93425B (en) 1994-12-30
DK23588D0 (en) 1988-01-20
FI93425C (en) 1995-04-10

Similar Documents

Publication Publication Date Title
NO176304C (en) Process for the preparation of pharmaceutical implants based on polylactide
FI885460A (en) Process for the preparation of a pharmaceutical composition for oral administration and controlled release of the active substance
AU7452887A (en) Controlled absorption pharmaceutical composition
NO893021D0 (en) PROCEDURE FOR PREPARING A BIOLOGICAL ACTIVE COMPOUND, FR 901228.
AU7405387A (en) Pharmaceutical compositions containing levodopa methyl ester, preparation and therapeutic applications thereof
HUT43843A (en) Process for production of derivatives of benzimidasole and medical compounds containing thereof
IL85144A (en) Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation
HUT38097A (en) Process for preparing substituted benzopyrans and pharmaceutical compositions containing them as active substances
FR2692263B1 (en) Process for the preparation of cyclic esters of alpha-hydroxycarboxylic acids.
IL88020A0 (en) Oral formulation of buspirone and salts thereof
HU900717D0 (en) Process for preparation of 3-pyroglutamyl-thyazolidine-4-carboxylic acid derivatives and pharmaceutical compositions containing that compounds
EG18643A (en) Pharmaceutical compositions containing trapidil,a process for the preparation thereof and related therapeutic use

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees