ZA88358B - Oral pharmaceutical preparation with delayed release of active substance - Google Patents

Oral pharmaceutical preparation with delayed release of active substance

Info

Publication number
ZA88358B
ZA88358B ZA88358A ZA88358A ZA88358B ZA 88358 B ZA88358 B ZA 88358B ZA 88358 A ZA88358 A ZA 88358A ZA 88358 A ZA88358 A ZA 88358A ZA 88358 B ZA88358 B ZA 88358B
Authority
ZA
South Africa
Prior art keywords
active substance
pharmaceutical preparation
delayed release
oral pharmaceutical
polymers
Prior art date
Application number
ZA88358A
Inventor
Bernd Zierenberg
Zierenberg Bernd
Bernhard Freund
Freund Bernhard
Dieter Bendix
Bendix Dieter
Guenther Entenmann
Entenmann Guenther
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA88358B publication Critical patent/ZA88358B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The medicinal preparation having controlled continuous release of active compound is prepared from an excipient based on biologically degradable cyclic carboxylic acid esters, oligomers derived therefrom and/or polymers.
ZA88358A 1987-01-21 1988-01-20 Oral pharmaceutical preparation with delayed release of active substance ZA88358B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873701625 DE3701625A1 (en) 1987-01-21 1987-01-21 PERORAL DRUG PREPARATION WITH DELAYED ACTIVE RELEASE

Publications (1)

Publication Number Publication Date
ZA88358B true ZA88358B (en) 1989-09-27

Family

ID=6319213

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA88358A ZA88358B (en) 1987-01-21 1988-01-20 Oral pharmaceutical preparation with delayed release of active substance

Country Status (14)

Country Link
EP (1) EP0275961B1 (en)
JP (1) JP2744240B2 (en)
KR (1) KR970002615B1 (en)
AT (1) ATE106718T1 (en)
AU (1) AU605824B2 (en)
CA (1) CA1329767C (en)
DE (2) DE3701625A1 (en)
DK (1) DK23588A (en)
FI (1) FI93425C (en)
IL (1) IL85144A (en)
MX (1) MX10146A (en)
NO (1) NO175352C (en)
NZ (1) NZ223228A (en)
ZA (1) ZA88358B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981696A (en) * 1986-12-22 1991-01-01 E. I. Du Pont De Nemours And Company Polylactide compositions
US4902515A (en) * 1988-04-28 1990-02-20 E. I. Dupont De Nemours And Company Polylactide compositions
FR2634770B1 (en) * 1988-07-29 1990-10-05 Rhone Poulenc Chimie EODABLE POLYESTER COMPOSITION CONTAINING IODINE FOR WATER TREATMENT
EP0423484B1 (en) * 1989-10-16 1993-11-03 PCD-Polymere Gesellschaft m.b.H. Tablet with sustained release
DE4041563A1 (en) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS
DE19500977C2 (en) * 1995-01-14 1999-01-07 Lohmann Therapie Syst Lts Solid drug form with active ingredient distributed in polymeric material
DE19908753C2 (en) 1999-02-20 2003-10-02 Jenapharm Gmbh Biodegradable, injectable oligomer-polymer composition
JP6557722B2 (en) 2014-05-30 2019-08-07 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド Biodegradable lipids for delivery of nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CA1098443A (en) * 1977-05-20 1981-03-31 Namassivaya Doddi Absorbable p-dioxanone polymer-drug compositions
DE2824112A1 (en) * 1978-06-01 1979-12-06 Garching Instrumente Micro-pellets of biodegradable polymeric carrier - esp. poly:hydroxy-carboxylic acid, and active ingredient e.g. narcotic antagonist
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS5966425A (en) * 1982-10-08 1984-04-14 Mitsui Toatsu Chem Inc Preparation of fine particle using biodegradable polymer
FR2557459B1 (en) * 1984-01-02 1986-05-30 Lhd Lab Hygiene Dietetique POLYCAPROLACTONE-BASED INERT MATRIX FOR ORAL ADMINISTRATION OF A MEDICAMENT, AND METHOD FOR PREPARING THE GALENIC FORM COMPRISING THE SAME

Also Published As

Publication number Publication date
DK23588D0 (en) 1988-01-20
NZ223228A (en) 1990-12-21
DE3889933D1 (en) 1994-07-14
NO880230L (en) 1988-07-22
ATE106718T1 (en) 1994-06-15
NO880230D0 (en) 1988-01-20
DK23588A (en) 1988-07-22
CA1329767C (en) 1994-05-24
MX10146A (en) 1993-09-01
EP0275961A2 (en) 1988-07-27
FI93425C (en) 1995-04-10
EP0275961A3 (en) 1990-11-22
FI93425B (en) 1994-12-30
JPS6419025A (en) 1989-01-23
DE3701625A1 (en) 1988-08-04
AU1065388A (en) 1988-07-28
KR970002615B1 (en) 1997-03-06
EP0275961B1 (en) 1994-06-08
JP2744240B2 (en) 1998-04-28
NO175352B (en) 1994-06-27
IL85144A (en) 1991-06-30
AU605824B2 (en) 1991-01-24
FI880210A0 (en) 1988-01-19
FI880210A (en) 1988-07-22
NO175352C (en) 1994-10-05
IL85144A0 (en) 1988-06-30
KR880008806A (en) 1988-09-13

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