DK174932B1 - Apolipoprotein B-specifikke monoklonale antistoffer og hybridomaer, som producerer disse antistoffer - Google Patents

Apolipoprotein B-specifikke monoklonale antistoffer og hybridomaer, som producerer disse antistoffer Download PDF

Info

Publication number
DK174932B1
DK174932B1 DK198704079A DK407987A DK174932B1 DK 174932 B1 DK174932 B1 DK 174932B1 DK 198704079 A DK198704079 A DK 198704079A DK 407987 A DK407987 A DK 407987A DK 174932 B1 DK174932 B1 DK 174932B1
Authority
DK
Denmark
Prior art keywords
receptor
apo
immunoreactant
ldl
apoprotein
Prior art date
Application number
DK198704079A
Other languages
Danish (da)
English (en)
Other versions
DK407987A (da
DK407987D0 (da
Inventor
Steven Young
Linda K Curtiss
Joseph L Witztum
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK407987D0 publication Critical patent/DK407987D0/da
Publication of DK407987A publication Critical patent/DK407987A/da
Application granted granted Critical
Publication of DK174932B1 publication Critical patent/DK174932B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198704079A 1986-08-06 1987-08-05 Apolipoprotein B-specifikke monoklonale antistoffer og hybridomaer, som producerer disse antistoffer DK174932B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89365986A 1986-08-06 1986-08-06
US89365986 1986-08-06

Publications (3)

Publication Number Publication Date
DK407987D0 DK407987D0 (da) 1987-08-05
DK407987A DK407987A (da) 1988-02-07
DK174932B1 true DK174932B1 (da) 2004-03-01

Family

ID=25401879

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198704079A DK174932B1 (da) 1986-08-06 1987-08-05 Apolipoprotein B-specifikke monoklonale antistoffer og hybridomaer, som producerer disse antistoffer

Country Status (13)

Country Link
US (2) US5330910A (de)
EP (1) EP0257778B1 (de)
JP (1) JP2831352B2 (de)
AT (1) ATE120233T1 (de)
AU (1) AU7657387A (de)
CA (1) CA1338032C (de)
DE (1) DE3751182T2 (de)
DK (1) DK174932B1 (de)
ES (1) ES2070820T3 (de)
FI (1) FI92714C (de)
IE (1) IE66195B1 (de)
NO (1) NO172596C (de)
PT (1) PT85490B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
JPH07104351B2 (ja) * 1988-09-29 1995-11-13 株式会社日本抗体研究所 脂質代謝異常検出用キット
KR950008684A (ko) * 1993-09-21 1995-04-19 쇼다 오사무 아포리포프로틴 b로 이루어진 엔도텔린 전환효소
US6107045A (en) 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
JPH1026621A (ja) * 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
US6506569B1 (en) * 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
US6716410B1 (en) * 1999-10-26 2004-04-06 The Regents Of The University Of California Reagents and methods for diagnosing, imaging and treating atherosclerotic disease
DE60237455D1 (de) * 2001-07-12 2010-10-07 Kyowa Medex Co Ltd Verfahren zur quantifizierung von denaturiertem lipoprotein
CN1968965B (zh) 2004-04-15 2015-12-16 阿瑟拉生物技术公司 磷酸胆碱偶联物和相应抗体
US7875182B2 (en) * 2006-11-20 2011-01-25 Cytosorbents, Inc. Size-selective hemoperfusion polymeric adsorbents
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
AR087485A1 (es) 2011-08-09 2014-03-26 Athera Biotechnologies Ab Anticuerpos de union a fosforilcolina (pc) y/o conjugados de pc
EP2741770A4 (de) 2011-08-09 2014-12-31 Athera Biotechnologies Ab Antikörperbindung an phosphorylcholin (pc) und/oder pc-konjugate
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
US10434141B2 (en) 2016-05-31 2019-10-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
JPS6015559A (ja) * 1983-07-06 1985-01-26 Shiraimatsu Shinyaku Kk アポリポ蛋白−ｂの酵素免疫測定試薬
DE3338836A1 (de) * 1983-10-26 1985-05-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60239425A (ja) * 1984-05-14 1985-11-28 Teijin Ltd 脂質代謝調節用固相担体
EP0209543A4 (de) * 1984-12-31 1989-07-11 Internat Genetic Engineering I Peptidfragmente menschlicher apolipoproteine, typspezifische antikörper und verwendungsverfahren.
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Also Published As

Publication number Publication date
AU7657387A (en) 1988-02-11
IE66195B1 (en) 1995-12-13
FI92714B (fi) 1994-09-15
IE872104L (en) 1988-02-06
PT85490A (en) 1987-09-01
FI873410A (fi) 1988-02-07
DK407987A (da) 1988-02-07
EP0257778A3 (en) 1990-03-21
DE3751182T2 (de) 1995-10-26
PT85490B (pt) 1990-06-29
EP0257778B1 (de) 1995-03-22
NO873271L (no) 1988-02-08
FI92714C (fi) 1994-12-27
US5460947A (en) 1995-10-24
NO172596C (no) 1993-08-11
NO172596B (no) 1993-05-03
ATE120233T1 (de) 1995-04-15
DK407987D0 (da) 1987-08-05
JPS63279783A (ja) 1988-11-16
ES2070820T3 (es) 1995-06-16
NO873271D0 (no) 1987-08-05
EP0257778A2 (de) 1988-03-02
FI873410A0 (fi) 1987-08-05
DE3751182D1 (de) 1995-04-27
JP2831352B2 (ja) 1998-12-02
CA1338032C (en) 1996-02-06
US5330910A (en) 1994-07-19

Similar Documents

Publication Publication Date Title
DK174932B1 (da) Apolipoprotein B-specifikke monoklonale antistoffer og hybridomaer, som producerer disse antistoffer
FI89214B (fi) Analysfoerfarande och diagnostiskt system foer ett markerande aemne foer abnorm lipidmetabolism
JP2505218B2 (ja) アポリポタンパクａ―１に対して特異性を有するモノクロ―ナル抗体又はそのパラト―プ含有ポリペプチド部分並びにそれを使用する診断装置
US20040106143A1 (en) Monoclonal antibody against estrogen stimulated leucine aminopeptidase
EP0218630A1 (de) Diagnosetestverfahren für die anwesenheit von mit plasmalipoproteinen hoher dichte assoziierten apolipoproteinen
Gulizia et al. Immunoreactivity of anti-streptococcal monoclonal antibodies to human heart valves. Evidence for multiple cross-reactive epitopes.
EP0433088A1 (de) Monoklonaler Antikörper spezifisch für ein humanes atherom-assoziiertes Antigen
EP0741144B1 (de) Monoklonaler antikörper gegen antiannexin-v, verfahren zu seiner herstellung und seiner verwendung
JPS62167479A (ja) ヒト銅・亜鉛−ス−パ−オキシドジスムタ−ゼのモノクロ−ナル抗体からなるヒト銅・亜鉛−ス−パ−オキシドジスムタ−ゼ測定用試薬およびそれを用いる胃癌の診断方法
KR100222232B1 (ko) 사람 리포단백질과 반응하는 모노클로날 항체 ferm bp-3755
IE881290L (en) Monoclonal antibodies for the selective immunological¹determination of intact procollagen peptide (Type III) and¹procollagen (Type III) in body fluids
JPH0431762A (ja) 心筋梗塞の判定方法
Milthorp et al. Immunological Characterization of Apolipoprotein AI from Normal Human Plasma: Mapping of Antigenic Determinants
Li Production, characterization, and use of monoclonal antibodies directed against bovine platelet thrombospondin

Legal Events

Date Code Title Description
PUP Patent expired