DE3751182D1 - Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden. - Google Patents

Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden.

Info

Publication number
DE3751182D1
DE3751182D1 DE3751182T DE3751182T DE3751182D1 DE 3751182 D1 DE3751182 D1 DE 3751182D1 DE 3751182 T DE3751182 T DE 3751182T DE 3751182 T DE3751182 T DE 3751182T DE 3751182 D1 DE3751182 D1 DE 3751182D1
Authority
DE
Germany
Prior art keywords
apolipoprotein
hybridomas
produced
specific
monoclonal antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3751182T
Other languages
English (en)
Other versions
DE3751182T2 (de
Inventor
Steven Young
Joseph L Witztum
Linda K Curtiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Application granted granted Critical
Publication of DE3751182D1 publication Critical patent/DE3751182D1/de
Publication of DE3751182T2 publication Critical patent/DE3751182T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3751182T 1986-08-06 1987-07-20 Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden. Expired - Lifetime DE3751182T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89365986A 1986-08-06 1986-08-06

Publications (2)

Publication Number Publication Date
DE3751182D1 true DE3751182D1 (de) 1995-04-27
DE3751182T2 DE3751182T2 (de) 1995-10-26

Family

ID=25401879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3751182T Expired - Lifetime DE3751182T2 (de) 1986-08-06 1987-07-20 Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden.

Country Status (13)

Country Link
US (2) US5330910A (de)
EP (1) EP0257778B1 (de)
JP (1) JP2831352B2 (de)
AT (1) ATE120233T1 (de)
AU (1) AU7657387A (de)
CA (1) CA1338032C (de)
DE (1) DE3751182T2 (de)
DK (1) DK174932B1 (de)
ES (1) ES2070820T3 (de)
FI (1) FI92714C (de)
IE (1) IE66195B1 (de)
NO (1) NO172596C (de)
PT (1) PT85490B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
JPH07104351B2 (ja) * 1988-09-29 1995-11-13 株式会社日本抗体研究所 脂質代謝異常検出用キット
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
KR950008684A (ko) * 1993-09-21 1995-04-19 쇼다 오사무 아포리포프로틴 b로 이루어진 엔도텔린 전환효소
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
JPH1026621A (ja) * 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
US6506569B1 (en) * 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
US6716410B1 (en) * 1999-10-26 2004-04-06 The Regents Of The University Of California Reagents and methods for diagnosing, imaging and treating atherosclerotic disease
JP4179988B2 (ja) * 2001-07-12 2008-11-12 協和メデックス株式会社 変性リポ蛋白質の定量法、変性リポ蛋白質の定量用試薬、循環器疾患の検出方法および循環器疾患の検出試薬
US8012483B2 (en) 2004-04-15 2011-09-06 Athera Biotechnologies Ab Phosphorylcholine conjugates and corresponding antibodies
US7875182B2 (en) * 2006-11-20 2011-01-25 Cytosorbents, Inc. Size-selective hemoperfusion polymeric adsorbents
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
US9796786B2 (en) 2011-08-09 2017-10-24 Athera Biotechnologies Ab Antibodies binding to phosphorylcholine (PC) and/or PC conjugates
AU2012293646B2 (en) 2011-08-09 2017-08-31 Athera Biotechnologies Ab New antibodies against phosphorylcholine
US10434141B2 (en) 2016-05-31 2019-10-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS6015559A (ja) * 1983-07-06 1985-01-26 Shiraimatsu Shinyaku Kk アポリポ蛋白−ｂの酵素免疫測定試薬
DE3338836A1 (de) * 1983-10-26 1985-05-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60239425A (ja) * 1984-05-14 1985-11-28 Teijin Ltd 脂質代謝調節用固相担体
EP0209543A4 (de) * 1984-12-31 1989-07-11 Internat Genetic Engineering I Peptidfragmente menschlicher apolipoproteine, typspezifische antikörper und verwendungsverfahren.
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Also Published As

Publication number Publication date
JPS63279783A (ja) 1988-11-16
CA1338032C (en) 1996-02-06
DK174932B1 (da) 2004-03-01
IE872104L (en) 1988-02-06
EP0257778A2 (de) 1988-03-02
DK407987D0 (da) 1987-08-05
EP0257778B1 (de) 1995-03-22
US5330910A (en) 1994-07-19
IE66195B1 (en) 1995-12-13
AU7657387A (en) 1988-02-11
DK407987A (da) 1988-02-07
FI873410A0 (fi) 1987-08-05
US5460947A (en) 1995-10-24
NO873271D0 (no) 1987-08-05
FI92714C (fi) 1994-12-27
ES2070820T3 (es) 1995-06-16
PT85490A (en) 1987-09-01
NO172596B (no) 1993-05-03
PT85490B (pt) 1990-06-29
DE3751182T2 (de) 1995-10-26
NO172596C (no) 1993-08-11
ATE120233T1 (de) 1995-04-15
NO873271L (no) 1988-02-08
FI92714B (fi) 1994-09-15
EP0257778A3 (en) 1990-03-21
FI873410A (fi) 1988-02-07
JP2831352B2 (ja) 1998-12-02

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