ATE120233T1 - Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden. - Google Patents

Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden.

Info

Publication number
ATE120233T1
ATE120233T1 AT87306413T AT87306413T ATE120233T1 AT E120233 T1 ATE120233 T1 AT E120233T1 AT 87306413 T AT87306413 T AT 87306413T AT 87306413 T AT87306413 T AT 87306413T AT E120233 T1 ATE120233 T1 AT E120233T1
Authority
AT
Austria
Prior art keywords
apolipoprotein
hybridomes
produced
specific
monoclonal antibodies
Prior art date
Application number
AT87306413T
Other languages
English (en)
Inventor
Steven Young
Joseph L Witztum
Linda K Curtiss
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE120233T1 publication Critical patent/ATE120233T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT87306413T 1986-08-06 1987-07-20 Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden. ATE120233T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89365986A 1986-08-06 1986-08-06

Publications (1)

Publication Number Publication Date
ATE120233T1 true ATE120233T1 (de) 1995-04-15

Family

ID=25401879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87306413T ATE120233T1 (de) 1986-08-06 1987-07-20 Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden.

Country Status (13)

Country Link
US (2) US5330910A (de)
EP (1) EP0257778B1 (de)
JP (1) JP2831352B2 (de)
AT (1) ATE120233T1 (de)
AU (1) AU7657387A (de)
CA (1) CA1338032C (de)
DE (1) DE3751182T2 (de)
DK (1) DK174932B1 (de)
ES (1) ES2070820T3 (de)
FI (1) FI92714C (de)
IE (1) IE66195B1 (de)
NO (1) NO172596C (de)
PT (1) PT85490B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
JPH07104351B2 (ja) * 1988-09-29 1995-11-13 株式会社日本抗体研究所 脂質代謝異常検出用キット
KR950008684A (ko) * 1993-09-21 1995-04-19 쇼다 오사무 아포리포프로틴 b로 이루어진 엔도텔린 전환효소
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
JPH1026621A (ja) * 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
US6506569B1 (en) * 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
US6716410B1 (en) * 1999-10-26 2004-04-06 The Regents Of The University Of California Reagents and methods for diagnosing, imaging and treating atherosclerotic disease
WO2003006989A1 (fr) * 2001-07-12 2003-01-23 Kyowa Medex Co., Ltd. Procede de quantification de lipoproteines denaturees, reactifs pour la quantification de lipoproteines denaturees, procede de detection de maladies du systeme circulatoire et reactifs pour la detection de maladies du systeme circulatoire
DE602005023428D1 (de) 2004-04-15 2010-10-21 Athera Biotechnologies Ab Verfahren zur Feststellung der Gefahren von ischemischen Herzgefässerkrankungen mit PhosphorylcholinKonjugaten
US7875182B2 (en) * 2006-11-20 2011-01-25 Cytosorbents, Inc. Size-selective hemoperfusion polymeric adsorbents
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
AU2012294431B2 (en) 2011-08-09 2017-03-30 Athera Biotechnologies Ab Antibodies binding to phosphorylcholine (PC) and/or PC conjugates
TR201909072T4 (tr) 2011-08-09 2019-08-21 Athera Biotechnologies Ab Fosforilkoline karşı yeni antikorlar.
EP3463416A1 (de) 2016-05-31 2019-04-10 CardioVax, LLC Verfahren zur diagnose und behandlung von systemischen lupus erythematodes
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS6015559A (ja) * 1983-07-06 1985-01-26 Shiraimatsu Shinyaku Kk アポリポ蛋白−ｂの酵素免疫測定試薬
DE3338836A1 (de) * 1983-10-26 1985-05-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Also Published As

Publication number Publication date
ES2070820T3 (es) 1995-06-16
IE872104L (en) 1988-02-06
FI873410L (fi) 1988-02-07
PT85490A (en) 1987-09-01
AU7657387A (en) 1988-02-11
JP2831352B2 (ja) 1998-12-02
JPS63279783A (ja) 1988-11-16
EP0257778A3 (en) 1990-03-21
CA1338032C (en) 1996-02-06
EP0257778B1 (de) 1995-03-22
NO873271L (no) 1988-02-08
US5330910A (en) 1994-07-19
DK407987A (da) 1988-02-07
US5460947A (en) 1995-10-24
IE66195B1 (en) 1995-12-13
FI92714B (fi) 1994-09-15
NO172596B (no) 1993-05-03
DE3751182T2 (de) 1995-10-26
FI92714C (fi) 1994-12-27
NO172596C (no) 1993-08-11
FI873410A0 (fi) 1987-08-05
DK407987D0 (da) 1987-08-05
NO873271D0 (no) 1987-08-05
DK174932B1 (da) 2004-03-01
EP0257778A2 (de) 1988-03-02
PT85490B (pt) 1990-06-29
DE3751182D1 (de) 1995-04-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time