ES2070820T3 - Anticuerpos monoclonales especificos de la apolipoproteina b, producidos por dos nuevos hibridomas. - Google Patents

Anticuerpos monoclonales especificos de la apolipoproteina b, producidos por dos nuevos hibridomas.

Info

Publication number
ES2070820T3
ES2070820T3 ES87306413T ES87306413T ES2070820T3 ES 2070820 T3 ES2070820 T3 ES 2070820T3 ES 87306413 T ES87306413 T ES 87306413T ES 87306413 T ES87306413 T ES 87306413T ES 2070820 T3 ES2070820 T3 ES 2070820T3
Authority
ES
Spain
Prior art keywords
apolipoprotein
hybridomes
produced
new
monoclonal antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87306413T
Other languages
English (en)
Inventor
Steven Young
Joseph L Witztum
Linda K Curtiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Application granted granted Critical
Publication of ES2070820T3 publication Critical patent/ES2070820T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE DESCUBRES DOS HIBRIDOMAS QUE PRODUCEN RECEPTORES QUE CONTIENEN NUCLEOS DE COMBINACION DE ANTICUERPOS QUE INMUNOREACCIONAN CON LA APOLIPROTEINA B-100, Y SE USAN COMO RECEPTORES, COMPOSICIONES Y SISTEMAS DE DIAGNOSTICO QUE INCLUYEN LOS RECEPTORES.
ES87306413T 1986-08-06 1987-07-20 Anticuerpos monoclonales especificos de la apolipoproteina b, producidos por dos nuevos hibridomas. Expired - Lifetime ES2070820T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89365986A 1986-08-06 1986-08-06

Publications (1)

Publication Number Publication Date
ES2070820T3 true ES2070820T3 (es) 1995-06-16

Family

ID=25401879

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87306413T Expired - Lifetime ES2070820T3 (es) 1986-08-06 1987-07-20 Anticuerpos monoclonales especificos de la apolipoproteina b, producidos por dos nuevos hibridomas.

Country Status (13)

Country Link
US (2) US5330910A (es)
EP (1) EP0257778B1 (es)
JP (1) JP2831352B2 (es)
AT (1) ATE120233T1 (es)
AU (1) AU7657387A (es)
CA (1) CA1338032C (es)
DE (1) DE3751182T2 (es)
DK (1) DK174932B1 (es)
ES (1) ES2070820T3 (es)
FI (1) FI92714C (es)
IE (1) IE66195B1 (es)
NO (1) NO172596C (es)
PT (1) PT85490B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
JPH07104351B2 (ja) * 1988-09-29 1995-11-13 株式会社日本抗体研究所 脂質代謝異常検出用キット
KR950008684A (ko) * 1993-09-21 1995-04-19 쇼다 오사무 아포리포프로틴 b로 이루어진 엔도텔린 전환효소
US6107045A (en) 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
JPH1026621A (ja) * 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
US6506569B1 (en) * 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
US6716410B1 (en) * 1999-10-26 2004-04-06 The Regents Of The University Of California Reagents and methods for diagnosing, imaging and treating atherosclerotic disease
DE60237455D1 (de) * 2001-07-12 2010-10-07 Kyowa Medex Co Ltd Verfahren zur quantifizierung von denaturiertem lipoprotein
CN1968965B (zh) 2004-04-15 2015-12-16 阿瑟拉生物技术公司 磷酸胆碱偶联物和相应抗体
US7875182B2 (en) * 2006-11-20 2011-01-25 Cytosorbents, Inc. Size-selective hemoperfusion polymeric adsorbents
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
AR087485A1 (es) 2011-08-09 2014-03-26 Athera Biotechnologies Ab Anticuerpos de union a fosforilcolina (pc) y/o conjugados de pc
EP2741770A4 (en) 2011-08-09 2014-12-31 Athera Biotechnologies Ab ANTIBODIES FOR BINDING TO PHOSPHORYLCHOLINE (PC) AND / OR PC CONJUGATE
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
US10434141B2 (en) 2016-05-31 2019-10-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
JPS6015559A (ja) * 1983-07-06 1985-01-26 Shiraimatsu Shinyaku Kk アポリポ蛋白−ｂの酵素免疫測定試薬
DE3338836A1 (de) * 1983-10-26 1985-05-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60239425A (ja) * 1984-05-14 1985-11-28 Teijin Ltd 脂質代謝調節用固相担体
EP0209543A4 (en) * 1984-12-31 1989-07-11 Internat Genetic Engineering I FRAGMENTS OF HUMAN APOLIPOPROTEINS PEPTIDES, TYPE-SPECIFIC ANTIBODIES AND METHODS OF USE.
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Also Published As

Publication number Publication date
AU7657387A (en) 1988-02-11
IE66195B1 (en) 1995-12-13
FI92714B (fi) 1994-09-15
IE872104L (en) 1988-02-06
PT85490A (en) 1987-09-01
FI873410A (fi) 1988-02-07
DK407987A (da) 1988-02-07
EP0257778A3 (en) 1990-03-21
DE3751182T2 (de) 1995-10-26
PT85490B (pt) 1990-06-29
DK174932B1 (da) 2004-03-01
EP0257778B1 (en) 1995-03-22
NO873271L (no) 1988-02-08
FI92714C (fi) 1994-12-27
US5460947A (en) 1995-10-24
NO172596C (no) 1993-08-11
NO172596B (no) 1993-05-03
ATE120233T1 (de) 1995-04-15
DK407987D0 (da) 1987-08-05
JPS63279783A (ja) 1988-11-16
NO873271D0 (no) 1987-08-05
EP0257778A2 (en) 1988-03-02
FI873410A0 (fi) 1987-08-05
DE3751182D1 (de) 1995-04-27
JP2831352B2 (ja) 1998-12-02
CA1338032C (en) 1996-02-06
US5330910A (en) 1994-07-19

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