DK172553B1 - Annellerede azepinonderivater og fysiologisk uskadelige salte deraf, deres anvendelse samt farmaceutisk præparat - Google Patents

Annellerede azepinonderivater og fysiologisk uskadelige salte deraf, deres anvendelse samt farmaceutisk præparat Download PDF

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Publication number
DK172553B1
DK172553B1 DK198800724A DK72488A DK172553B1 DK 172553 B1 DK172553 B1 DK 172553B1 DK 198800724 A DK198800724 A DK 198800724A DK 72488 A DK72488 A DK 72488A DK 172553 B1 DK172553 B1 DK 172553B1
Authority
DK
Denmark
Prior art keywords
oxo
formula
azepine
compounds
perhydrocyclopent
Prior art date
Application number
DK198800724A
Other languages
Danish (da)
English (en)
Other versions
DK72488A (da
DK72488D0 (da
Inventor
Hansjoerg Urbach
Rainer Henning
Reinhard Becker
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK72488D0 publication Critical patent/DK72488D0/da
Publication of DK72488A publication Critical patent/DK72488A/da
Application granted granted Critical
Publication of DK172553B1 publication Critical patent/DK172553B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
DK198800724A 1987-02-14 1988-02-12 Annellerede azepinonderivater og fysiologisk uskadelige salte deraf, deres anvendelse samt farmaceutisk præparat DK172553B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873704661 DE3704661A1 (de) 1987-02-14 1987-02-14 Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung
DE3704661 1987-02-14

Publications (3)

Publication Number Publication Date
DK72488D0 DK72488D0 (da) 1988-02-12
DK72488A DK72488A (da) 1988-08-15
DK172553B1 true DK172553B1 (da) 1999-01-11

Family

ID=6320980

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198800724A DK172553B1 (da) 1987-02-14 1988-02-12 Annellerede azepinonderivater og fysiologisk uskadelige salte deraf, deres anvendelse samt farmaceutisk præparat

Country Status (26)

Country Link
US (1) US4857520A (fr)
EP (1) EP0279350B1 (fr)
JP (1) JP2638034B2 (fr)
KR (1) KR960011376B1 (fr)
AR (1) AR246957A1 (fr)
AT (1) ATE97913T1 (fr)
AU (1) AU610124B2 (fr)
CA (1) CA1313371C (fr)
CZ (1) CZ280148B6 (fr)
DD (1) DD279877A5 (fr)
DE (2) DE3704661A1 (fr)
DK (1) DK172553B1 (fr)
ES (1) ES2061531T3 (fr)
FI (1) FI86849C (fr)
HU (2) HU208425B (fr)
IE (1) IE62354B1 (fr)
IL (1) IL85406A (fr)
JO (1) JO1524B1 (fr)
MA (1) MA21181A1 (fr)
MX (1) MX174166B (fr)
NO (1) NO176763C (fr)
NZ (1) NZ223500A (fr)
PH (1) PH25186A (fr)
PT (1) PT86748B (fr)
TN (1) TNSN88010A1 (fr)
ZA (1) ZA88991B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
RU2276997C2 (ru) * 1999-08-30 2006-05-27 Санофи-Авентис Дойчланд Гмбх Применение ингибиторов ренин-ангиотензиновой системы для профилактики сердечно-сосудистых явлений

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354146A (en) * 1967-11-21 Process for the production of cyclo- pentano omega-oenantholactam
US4141893A (en) * 1976-11-02 1979-02-27 Eli Lilly And Company Decahydrocyclopent[c]azepines
CY1403A (en) * 1981-08-11 1987-12-18 Ciba Geigy Ag Benzazepin-2-ones
DE3373469D1 (en) * 1982-09-30 1987-10-15 Merck & Co Inc 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
DE3426720A1 (de) * 1984-07-20 1986-01-23 Hoechst Ag, 6230 Frankfurt Benzthiazepinon- und benzthiazocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Also Published As

Publication number Publication date
NO176763C (no) 1995-05-24
AU1167288A (en) 1988-08-18
CA1313371C (fr) 1993-02-02
PT86748B (pt) 1992-04-30
DE3704661A1 (de) 1988-08-25
AU610124B2 (en) 1991-05-16
DE3885914D1 (de) 1994-01-13
HU208425B (en) 1993-10-28
FI86849B (fi) 1992-07-15
ZA88991B (en) 1988-08-10
MX10408A (es) 1993-07-01
KR880009939A (ko) 1988-10-06
TNSN88010A1 (fr) 1990-07-10
NO176763B (no) 1995-02-13
EP0279350B1 (fr) 1993-12-01
IL85406A0 (en) 1988-07-31
HUT48602A (en) 1989-06-28
DK72488A (da) 1988-08-15
IE62354B1 (en) 1995-01-25
CZ89288A3 (en) 1994-12-15
HUT50785A (en) 1990-03-28
NO880628L (no) 1988-08-15
IL85406A (en) 1992-06-21
PT86748A (pt) 1988-03-01
IE880390L (en) 1988-08-14
FI880632A0 (fi) 1988-02-11
MX174166B (es) 1994-04-26
US4857520A (en) 1989-08-15
PH25186A (en) 1991-03-27
NZ223500A (en) 1990-11-27
AR246957A1 (es) 1994-10-31
JPS63203665A (ja) 1988-08-23
NO880628D0 (no) 1988-02-12
JO1524B1 (en) 1989-01-25
MA21181A1 (fr) 1988-10-01
ES2061531T3 (es) 1994-12-16
EP0279350A2 (fr) 1988-08-24
CZ280148B6 (cs) 1995-11-15
FI86849C (fi) 1992-10-26
DK72488D0 (da) 1988-02-12
ATE97913T1 (de) 1993-12-15
EP0279350A3 (en) 1990-09-05
KR960011376B1 (ko) 1996-08-22
DD279877A5 (de) 1990-06-20
FI880632A (fi) 1988-08-15
JP2638034B2 (ja) 1997-08-06
HU203727B (en) 1991-09-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed