ZA88991B - Fused azepinone and azocinone derivatives,processes for their preparation,agents containing them and their use,and intermediates in their preparation - Google Patents

Fused azepinone and azocinone derivatives,processes for their preparation,agents containing them and their use,and intermediates in their preparation

Info

Publication number
ZA88991B
ZA88991B ZA880991A ZA88991A ZA88991B ZA 88991 B ZA88991 B ZA 88991B ZA 880991 A ZA880991 A ZA 880991A ZA 88991 A ZA88991 A ZA 88991A ZA 88991 B ZA88991 B ZA 88991B
Authority
ZA
South Africa
Prior art keywords
preparation
azocinone
intermediates
derivatives
processes
Prior art date
Application number
ZA880991A
Other languages
English (en)
Inventor
Urbach Hansjoerg
Henning Rainer
Schoelkens Bernward
Becker Reinhard
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA88991B publication Critical patent/ZA88991B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA880991A 1987-02-14 1988-02-12 Fused azepinone and azocinone derivatives,processes for their preparation,agents containing them and their use,and intermediates in their preparation ZA88991B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873704661 DE3704661A1 (de) 1987-02-14 1987-02-14 Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA88991B true ZA88991B (en) 1988-08-10

Family

ID=6320980

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA880991A ZA88991B (en) 1987-02-14 1988-02-12 Fused azepinone and azocinone derivatives,processes for their preparation,agents containing them and their use,and intermediates in their preparation

Country Status (26)

Country Link
US (1) US4857520A (xx)
EP (1) EP0279350B1 (xx)
JP (1) JP2638034B2 (xx)
KR (1) KR960011376B1 (xx)
AR (1) AR246957A1 (xx)
AT (1) ATE97913T1 (xx)
AU (1) AU610124B2 (xx)
CA (1) CA1313371C (xx)
CZ (1) CZ280148B6 (xx)
DD (1) DD279877A5 (xx)
DE (2) DE3704661A1 (xx)
DK (1) DK172553B1 (xx)
ES (1) ES2061531T3 (xx)
FI (1) FI86849C (xx)
HU (2) HU208425B (xx)
IE (1) IE62354B1 (xx)
IL (1) IL85406A (xx)
JO (1) JO1524B1 (xx)
MA (1) MA21181A1 (xx)
MX (1) MX174166B (xx)
NO (1) NO176763C (xx)
NZ (1) NZ223500A (xx)
PH (1) PH25186A (xx)
PT (1) PT86748B (xx)
TN (1) TNSN88010A1 (xx)
ZA (1) ZA88991B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
TR200200515T2 (tr) * 1999-08-30 2002-11-21 Aventis Pharma Deutschland Gmbh Renin-anjiyotensin sistem önleyicilerinin kardiyovasküler vakaların engellenmesinde kullanılması.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354146A (en) * 1967-11-21 Process for the production of cyclo- pentano omega-oenantholactam
US4141893A (en) * 1976-11-02 1979-02-27 Eli Lilly And Company Decahydrocyclopent[c]azepines
CY1403A (en) * 1981-08-11 1987-12-18 Ciba Geigy Ag Benzazepin-2-ones
DE3373469D1 (en) * 1982-09-30 1987-10-15 Merck & Co Inc 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
DE3426720A1 (de) * 1984-07-20 1986-01-23 Hoechst Ag, 6230 Frankfurt Benzthiazepinon- und benzthiazocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Also Published As

Publication number Publication date
JP2638034B2 (ja) 1997-08-06
AR246957A1 (es) 1994-10-31
JO1524B1 (en) 1989-01-25
FI880632A0 (fi) 1988-02-11
NZ223500A (en) 1990-11-27
NO880628L (no) 1988-08-15
EP0279350A3 (en) 1990-09-05
DD279877A5 (de) 1990-06-20
FI880632A (fi) 1988-08-15
AU1167288A (en) 1988-08-18
DE3885914D1 (de) 1994-01-13
PH25186A (en) 1991-03-27
PT86748B (pt) 1992-04-30
NO880628D0 (no) 1988-02-12
MX174166B (es) 1994-04-26
HUT48602A (en) 1989-06-28
NO176763C (no) 1995-05-24
FI86849C (fi) 1992-10-26
CZ89288A3 (en) 1994-12-15
TNSN88010A1 (fr) 1990-07-10
HU203727B (en) 1991-09-30
DK72488A (da) 1988-08-15
ATE97913T1 (de) 1993-12-15
DK172553B1 (da) 1999-01-11
HU208425B (en) 1993-10-28
IL85406A0 (en) 1988-07-31
US4857520A (en) 1989-08-15
EP0279350B1 (de) 1993-12-01
NO176763B (no) 1995-02-13
IL85406A (en) 1992-06-21
JPS63203665A (ja) 1988-08-23
MX10408A (es) 1993-07-01
CA1313371C (en) 1993-02-02
MA21181A1 (fr) 1988-10-01
CZ280148B6 (cs) 1995-11-15
KR880009939A (ko) 1988-10-06
ES2061531T3 (es) 1994-12-16
EP0279350A2 (de) 1988-08-24
IE880390L (en) 1988-08-14
FI86849B (fi) 1992-07-15
PT86748A (pt) 1988-03-01
DK72488D0 (da) 1988-02-12
IE62354B1 (en) 1995-01-25
AU610124B2 (en) 1991-05-16
KR960011376B1 (ko) 1996-08-22
HUT50785A (en) 1990-03-28
DE3704661A1 (de) 1988-08-25

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