DK171644B1 - 2-Biheterocyklothiopenemderivater samt mellemprodukt til disses fremstilling - Google Patents

2-Biheterocyklothiopenemderivater samt mellemprodukt til disses fremstilling Download PDF

Info

Publication number
DK171644B1
DK171644B1 DK283586A DK283586A DK171644B1 DK 171644 B1 DK171644 B1 DK 171644B1 DK 283586 A DK283586 A DK 283586A DK 283586 A DK283586 A DK 283586A DK 171644 B1 DK171644 B1 DK 171644B1
Authority
DK
Denmark
Prior art keywords
ppm
added
compound
solvent
dihydro
Prior art date
Application number
DK283586A
Other languages
Danish (da)
English (en)
Other versions
DK283586A (da
DK283586D0 (da
Inventor
Makoto Sato
Makoto Takemura
Kunio Higashi
Tsunehiko Sosa
Hiroo Matsumoto
Toshiyuki Nishi
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of DK283586D0 publication Critical patent/DK283586D0/da
Publication of DK283586A publication Critical patent/DK283586A/da
Application granted granted Critical
Publication of DK171644B1 publication Critical patent/DK171644B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pens And Brushes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Electrotherapy Devices (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
DK283586A 1985-06-17 1986-06-17 2-Biheterocyklothiopenemderivater samt mellemprodukt til disses fremstilling DK171644B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP13139485 1985-06-17
JP13139485 1985-06-17
JP21342085 1985-09-26
JP21342085 1985-09-26

Publications (3)

Publication Number Publication Date
DK283586D0 DK283586D0 (da) 1986-06-17
DK283586A DK283586A (da) 1986-12-18
DK171644B1 true DK171644B1 (da) 1997-03-03

Family

ID=26466241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK283586A DK171644B1 (da) 1985-06-17 1986-06-17 2-Biheterocyklothiopenemderivater samt mellemprodukt til disses fremstilling

Country Status (14)

Country Link
US (2) US4962202A (sh)
EP (1) EP0210883B1 (sh)
JP (2) JPH0826040B2 (sh)
AT (1) ATE118007T1 (sh)
AU (2) AU593558B2 (sh)
CA (1) CA1339860C (sh)
DE (1) DE3650221T2 (sh)
DK (1) DK171644B1 (sh)
ES (1) ES8801286A1 (sh)
FI (1) FI87218C (sh)
GR (1) GR861568B (sh)
IE (1) IE67525B1 (sh)
NO (1) NO167982C (sh)
YU (1) YU46172B (sh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339860C (en) * 1985-06-17 1998-05-12 Tsunehiko Soga Derivatives of penem
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
JP2579472B2 (ja) * 1986-12-17 1997-02-05 第一製薬株式会社 ペネム化合物
JP2708576B2 (ja) * 1988-11-08 1998-02-04 第一製薬株式会社 カルバペネム誘導体
US5541694A (en) * 1993-05-24 1996-07-30 Nikon Corporation Light shielding blade caulking pin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS58198486A (ja) * 1982-05-14 1983-11-18 Sankyo Co Ltd ペネムまたはカルバペネム−３−カルボン酸誘導体およびその製法
US4748162A (en) * 1982-03-01 1988-05-31 Merck & Co., Inc. 6-substituted-2-carbaminidoyl-pen-2-em-3-carboxylic acids
US4650794A (en) * 1982-04-29 1987-03-17 Merck & Co., Inc. 6-(1-hydroxyethyl)-2-carbamimidoyl-pen-2-em-3-carboxylic acids
JPS58180490A (ja) * 1982-03-01 1983-10-21 メルク・エンド・カムパニ−・インコ−ポレ−テツド ６−置換−２−カルバムイミドイル−ペン−２−エム−３−カルボン酸
NO831160L (no) * 1982-04-08 1983-10-10 Erba Farmitalia Fremstilling av substituerte penem-derivater
ZA836966B (en) * 1982-09-28 1984-04-25 Bristol Myers Co Carbapenem antibiotics
ZA841781B (en) * 1983-03-14 1985-07-31 Schering Corp Penim compounds,methods for their preparation and pharmaceutical compositions containing them
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
CA1273011A (en) * 1984-07-02 1990-08-21 Susan M. Schmitt Carbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
IE851586L (en) * 1984-07-02 1986-01-02 Interchem Internat S A I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
GB8509180D0 (en) * 1985-04-10 1985-05-15 Erba Farmitalia Penem derivatives
CA1339860C (en) * 1985-06-17 1998-05-12 Tsunehiko Soga Derivatives of penem
JP2579472B2 (ja) * 1986-12-17 1997-02-05 第一製薬株式会社 ペネム化合物

Also Published As

Publication number Publication date
US4962202A (en) 1990-10-09
FI87218C (fi) 1992-12-10
DE3650221D1 (de) 1995-03-16
FI862566A (fi) 1986-12-18
EP0210883B1 (en) 1995-02-01
DE3650221T2 (de) 1995-06-22
JPH0826040B2 (ja) 1996-03-13
DK283586A (da) 1986-12-18
AU4478489A (en) 1990-03-08
GR861568B (en) 1986-10-17
JP2691678B2 (ja) 1997-12-17
YU104986A (en) 1988-02-29
JPS62149683A (ja) 1987-07-03
YU46172B (sh) 1993-05-28
AU5890986A (en) 1986-12-24
AU593558B2 (en) 1990-02-15
EP0210883A2 (en) 1987-02-04
EP0210883A3 (en) 1987-07-01
NO167982C (no) 1992-01-02
CA1339860C (en) 1998-05-12
US5079357A (en) 1992-01-07
ES8801286A1 (es) 1988-01-01
NO862411D0 (no) 1986-06-17
ATE118007T1 (de) 1995-02-15
ES556137A0 (es) 1988-01-01
FI87218B (fi) 1992-08-31
IE67525B1 (en) 1996-04-03
JPH06184146A (ja) 1994-07-05
IE861593L (en) 1986-12-17
NO862411L (no) 1986-12-18
FI862566A0 (fi) 1986-06-17
NO167982B (no) 1991-09-23
DK283586D0 (da) 1986-06-17
AU626606B2 (en) 1992-08-06

Similar Documents

Publication Publication Date Title
US20230339960A1 (en) Bicyclic-Fused Heteroaryl or Aryl Compounds
JP6974331B2 (ja) 化合物、組成物及び方法
JPS60202886A (ja) １―置換カルバペネム―３―カルボン酸誘導体
CN101321726A (zh) 新型稠合吡咯衍生物
HU221041B1 (hu) (Trifluor-metil)-pirrolo-indol-karbonsav-észterek, eljárás az előállításukra és intermediereik
JPH0745500B2 (ja) １−メチルカルバペネム誘導体及びその製法
US6825187B2 (en) Carbapenem derivatives of quarternary salt type
DK171644B1 (da) 2-Biheterocyklothiopenemderivater samt mellemprodukt til disses fremstilling
JP2021527102A (ja) ガレクチン−３抑制剤を模したテトラヒドロピラン系チオ二糖類
JP2023515780A (ja) ヘテロ環状ｐａｄ４阻害剤
CN111542516B (zh) Irak4抑制剂及其用途
EP1022279B1 (en) New carbapenem derivatives
EP0167100A1 (en) Penem derivatives
JPH0463076B2 (sh)
KR930004012B1 (ko) 페넴 유도체의 제조방법
JPH0625243A (ja) １−メチルカルバペネム誘導体の製造法
WO1995014692A1 (en) Cabapenem derivatives and processes for preparing the same
CN116323606A (zh) 用于治疗整合素相关疾病的氮杂环丁烷衍生物
CN112279853A (zh) 一种选择性jak1抑制剂化合物及其制备方法和用途
JPH1045758A (ja) カルバペネム化合物、その製造法および剤
JP2004516298A (ja) ストレプトグラミン誘導体、その製造およびそれを含有する組成物

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed