DK170671B1 - Svovlholdigt antitumorantibiotikum betegnet BBM-1675D, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende BBM-1675D - Google Patents

Svovlholdigt antitumorantibiotikum betegnet BBM-1675D, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende BBM-1675D Download PDF

Info

Publication number
DK170671B1
DK170671B1 DK406086A DK406086A DK170671B1 DK 170671 B1 DK170671 B1 DK 170671B1 DK 406086 A DK406086 A DK 406086A DK 406086 A DK406086 A DK 406086A DK 170671 B1 DK170671 B1 DK 170671B1
Authority
DK
Denmark
Prior art keywords
bbm
sulfur
spectrum
antibiotic designated
methanol
Prior art date
Application number
DK406086A
Other languages
Danish (da)
English (en)
Other versions
DK406086A (da
DK406086D0 (da
Inventor
Jerzy Golik
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of DK406086D0 publication Critical patent/DK406086D0/da
Publication of DK406086A publication Critical patent/DK406086A/da
Application granted granted Critical
Publication of DK170671B1 publication Critical patent/DK170671B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK406086A 1985-08-27 1986-08-26 Svovlholdigt antitumorantibiotikum betegnet BBM-1675D, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende BBM-1675D DK170671B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27
US77033585 1985-08-27

Publications (3)

Publication Number Publication Date
DK406086D0 DK406086D0 (da) 1986-08-26
DK406086A DK406086A (da) 1987-02-28
DK170671B1 true DK170671B1 (da) 1995-11-27

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
DK406086A DK170671B1 (da) 1985-08-27 1986-08-26 Svovlholdigt antitumorantibiotikum betegnet BBM-1675D, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende BBM-1675D

Country Status (26)

Country Link
JP (2) JPH0733393B2 (fi)
KR (1) KR920010226B1 (fi)
AT (1) AT392971B (fi)
AU (1) AU604464B2 (fi)
BE (1) BE905332A (fi)
CA (1) CA1307256C (fi)
CH (1) CH668598A5 (fi)
CY (1) CY1676A (fi)
DE (1) DE3629052C2 (fi)
DK (1) DK170671B1 (fi)
ES (1) ES2002728A6 (fi)
FI (1) FI83422C (fi)
FR (1) FR2586686B1 (fi)
GB (1) GB2179649A (fi)
GR (1) GR862160B (fi)
HK (1) HK793A (fi)
HU (1) HU197915B (fi)
IE (1) IE59204B1 (fi)
IL (1) IL79519A0 (fi)
IT (1) IT1229176B (fi)
LU (1) LU86562A1 (fi)
NL (1) NL8602165A (fi)
PT (1) PT83261B (fi)
SE (2) SE469632B (fi)
SG (1) SG109692G (fi)
ZA (1) ZA865796B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質sf−2288及びその製造法
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
DK406086A (da) 1987-02-28
IT8621527A0 (it) 1986-08-26
IL79519A0 (en) 1986-10-31
GB2179649B (fi) 1989-10-25
ZA865796B (en) 1987-04-29
SE469632B (sv) 1993-08-09
ATA231786A (de) 1990-12-15
IE862280L (en) 1987-02-27
IT1229176B (it) 1991-07-23
GR862160B (en) 1986-12-31
FI83422C (fi) 1991-07-10
JPH0733393B2 (ja) 1995-04-12
GB2179649A (en) 1987-03-11
KR870002269A (ko) 1987-03-30
SE8603597D0 (sv) 1986-08-26
FI83422B (fi) 1991-03-28
HUT44035A (en) 1988-01-28
SE9200428D0 (sv) 1992-02-13
ES2002728A6 (es) 1988-10-01
GB8620118D0 (en) 1986-10-01
AT392971B (de) 1991-07-25
IE59204B1 (en) 1994-01-26
HU197915B (en) 1989-06-28
NL8602165A (nl) 1987-03-16
FI863405A (fi) 1987-02-28
DE3629052A1 (de) 1987-05-07
LU86562A1 (fr) 1987-03-06
SG109692G (en) 1992-12-24
PT83261A (en) 1986-09-01
DE3629052C2 (de) 1995-09-28
DK406086D0 (da) 1986-08-26
CA1307256C (en) 1992-09-08
AU604464B2 (en) 1990-12-20
AU6175186A (en) 1987-03-05
FI863405A0 (fi) 1986-08-22
FR2586686B1 (fr) 1990-02-02
JPH07233186A (ja) 1995-09-05
CH668598A5 (de) 1989-01-13
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
JPS62116589A (ja) 1987-05-28
SE9200428L (sv) 1993-08-14
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
FR2586686A1 (fr) 1987-03-06
HK793A (en) 1993-01-15
KR920010226B1 (ko) 1992-11-21

Similar Documents

Publication Publication Date Title
US4518589A (en) BBM-2478 Antibiotic complex
US4837206A (en) Esperamicin derivatives
DK170671B1 (da) Svovlholdigt antitumorantibiotikum betegnet BBM-1675D, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende BBM-1675D
DK145200B (da) Fremgangsmaade til fremstilling af anthtacyclinglycosid-antibiotika
US4960755A (en) BU-3608 derivatives
DK158739B (da) Svovlholdige antibiotiske og cytotoxiske forbindelser, betegnet cl-1577d og cl-1577e, fremgangsmaade til fremstilling af disse, samt farmaceutiske praeparater indeholdende forbindelserne
CA2673506A1 (en) Antibacterial compounds and processes for its production
DK146282B (da) Fremgangsmaade til fremstilling af anthracyclin-glycosid-antibiotika, kaldet rhodirubin a og b eller salte eller deoxyribonukleinsyrekomplekser deraf
SU751332A3 (ru) Способ получени антибиотического комплекса а-35512
HU205932B (en) Process for producing triacetate derivative of bu-3420t antibioticum and pharmaceutical compositions containing them
US4921700A (en) BBM-1675c and d antitumor antibiotics
US4847387A (en) Antibiotic compounds DC-92B and DC-92D
AT393691B (de) Verfahren zur herstellung des neuen antitumorantibiotikum-komplexes bbm-1675
US5994543A (en) Antibiotic bravomicins
KR100862546B1 (ko) 칼로포로사이드 유도체, 이의 제조방법 및 이를 포함하는 의약
EP0056290B1 (en) Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions
DE2118636A1 (de) 3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
US4572895A (en) Process for preparing an antibiotic complex by culturing actinomyces strain ATCC 39417
US5229371A (en) Chemical modification of elsamicin A at the 3' and/or 4' OH groups
JPH0578322A (ja) 新規抗生物質sf2738物質及びその製造法並びに制癌剤
EP0447494A1 (en) Altromycin compounds
CA1189856A (en) Semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
IE921765A1 (en) Chemical modification of elsamicin a at the 3' and/or 4'oh¹groups
KR840000127B1 (ko) 이스타마이신의 제조방법
EP0423247B1 (en) Coumamidine compounds

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed