JPH0733393B2 - 新規bbm―1675c抗腫瘍性抗生物質 - Google Patents

新規bbm―1675c抗腫瘍性抗生物質

Info

Publication number
JPH0733393B2
JPH0733393B2 JP61201199A JP20119986A JPH0733393B2 JP H0733393 B2 JPH0733393 B2 JP H0733393B2 JP 61201199 A JP61201199 A JP 61201199A JP 20119986 A JP20119986 A JP 20119986A JP H0733393 B2 JPH0733393 B2 JP H0733393B2
Authority
JP
Japan
Prior art keywords
bbm
antibiotic
antitumor
cdcl
magnetic resonance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61201199A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62116589A (ja
Inventor
ゴーリック ジャージー
Original Assignee
ブリストル―マイアーズ スクイブ コムパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ブリストル―マイアーズ スクイブ コムパニー filed Critical ブリストル―マイアーズ スクイブ コムパニー
Publication of JPS62116589A publication Critical patent/JPS62116589A/ja
Publication of JPH0733393B2 publication Critical patent/JPH0733393B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
JP61201199A 1985-08-27 1986-08-27 新規bbm―1675c抗腫瘍性抗生物質 Expired - Lifetime JPH0733393B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27
US770335 1985-08-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP6195156A Division JPH07233186A (ja) 1985-08-27 1994-08-19 新規bbm−1675d抗腫瘍性抗生物質

Publications (2)

Publication Number Publication Date
JPS62116589A JPS62116589A (ja) 1987-05-28
JPH0733393B2 true JPH0733393B2 (ja) 1995-04-12

Family

ID=25088206

Family Applications (2)

Application Number Title Priority Date Filing Date
JP61201199A Expired - Lifetime JPH0733393B2 (ja) 1985-08-27 1986-08-27 新規bbm―1675c抗腫瘍性抗生物質
JP6195156A Pending JPH07233186A (ja) 1985-08-27 1994-08-19 新規bbm−1675d抗腫瘍性抗生物質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP6195156A Pending JPH07233186A (ja) 1985-08-27 1994-08-19 新規bbm−1675d抗腫瘍性抗生物質

Country Status (26)

Country Link
JP (2) JPH0733393B2 (fi)
KR (1) KR920010226B1 (fi)
AT (1) AT392971B (fi)
AU (1) AU604464B2 (fi)
BE (1) BE905332A (fi)
CA (1) CA1307256C (fi)
CH (1) CH668598A5 (fi)
CY (1) CY1676A (fi)
DE (1) DE3629052C2 (fi)
DK (1) DK170671B1 (fi)
ES (1) ES2002728A6 (fi)
FI (1) FI83422C (fi)
FR (1) FR2586686B1 (fi)
GB (1) GB2179649A (fi)
GR (1) GR862160B (fi)
HK (1) HK793A (fi)
HU (1) HU197915B (fi)
IE (1) IE59204B1 (fi)
IL (1) IL79519A0 (fi)
IT (1) IT1229176B (fi)
LU (1) LU86562A1 (fi)
NL (1) NL8602165A (fi)
PT (1) PT83261B (fi)
SE (2) SE469632B (fi)
SG (1) SG109692G (fi)
ZA (1) ZA865796B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質sf−2288及びその製造法
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
DK406086A (da) 1987-02-28
IT8621527A0 (it) 1986-08-26
IL79519A0 (en) 1986-10-31
GB2179649B (fi) 1989-10-25
ZA865796B (en) 1987-04-29
SE469632B (sv) 1993-08-09
DK170671B1 (da) 1995-11-27
ATA231786A (de) 1990-12-15
IE862280L (en) 1987-02-27
IT1229176B (it) 1991-07-23
GR862160B (en) 1986-12-31
FI83422C (fi) 1991-07-10
GB2179649A (en) 1987-03-11
KR870002269A (ko) 1987-03-30
SE8603597D0 (sv) 1986-08-26
FI83422B (fi) 1991-03-28
HUT44035A (en) 1988-01-28
SE9200428D0 (sv) 1992-02-13
ES2002728A6 (es) 1988-10-01
GB8620118D0 (en) 1986-10-01
AT392971B (de) 1991-07-25
IE59204B1 (en) 1994-01-26
HU197915B (en) 1989-06-28
NL8602165A (nl) 1987-03-16
FI863405A (fi) 1987-02-28
DE3629052A1 (de) 1987-05-07
LU86562A1 (fr) 1987-03-06
SG109692G (en) 1992-12-24
PT83261A (en) 1986-09-01
DE3629052C2 (de) 1995-09-28
DK406086D0 (da) 1986-08-26
CA1307256C (en) 1992-09-08
AU604464B2 (en) 1990-12-20
AU6175186A (en) 1987-03-05
FI863405A0 (fi) 1986-08-22
FR2586686B1 (fr) 1990-02-02
JPH07233186A (ja) 1995-09-05
CH668598A5 (de) 1989-01-13
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
JPS62116589A (ja) 1987-05-28
SE9200428L (sv) 1993-08-14
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
FR2586686A1 (fr) 1987-03-06
HK793A (en) 1993-01-15
KR920010226B1 (ko) 1992-11-21

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