IE59204B1 - Antibiotics - Google Patents
AntibioticsInfo
- Publication number
- IE59204B1 IE59204B1 IE228086A IE228086A IE59204B1 IE 59204 B1 IE59204 B1 IE 59204B1 IE 228086 A IE228086 A IE 228086A IE 228086 A IE228086 A IE 228086A IE 59204 B1 IE59204 B1 IE 59204B1
- Authority
- IE
- Ireland
- Prior art keywords
- bbm
- exhibiting
- antibiotic
- spectrum
- antitumor
- Prior art date
Links
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- AUJXLBOHYWTPFV-RQLJINDISA-N n-[(4s,7r,11s,17s,20r,24s)-2,4,12,15,17,25-hexamethyl-29-methylsulfanyl-3,6,10,13,16,19,23,26-octaoxo-11,24-di(propan-2-yl)-7-(quinoxaline-2-carbonylamino)-9,22-dioxa-28-thia-2,5,12,15,18,25-hexazabicyclo[12.12.3]nonacosan-20-yl]quinoxaline-2-carboxamide Chemical compound C([C@H](C(=O)N[C@@H](C)C(=O)N1C)NC(=O)C=2N=C3C=CC=CC3=NC=2)OC(=O)[C@H](C(C)C)N(C)C(=O)C2N(C)C(=O)[C@H](C)NC(=O)[C@H](NC(=O)C=3N=C4C=CC=CC4=NC=3)COC(=O)[C@H](C(C)C)N(C)C(=O)C1CSC2SC AUJXLBOHYWTPFV-RQLJINDISA-N 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229960003171 plicamycin Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- RAGFPHFDFVNLCG-INYQBOQCSA-N sibiromycin Chemical compound O[C@@H]1[C@@](O)(C)[C@@H](NC)[C@H](C)O[C@H]1OC(C(=C1O)C)=CC(C2=O)=C1N[C@H](O)[C@H]1N2C=C(\C=C\C)C1 RAGFPHFDFVNLCG-INYQBOQCSA-N 0.000 description 1
- RAGFPHFDFVNLCG-UHFFFAOYSA-N sibiromycin Natural products OC1C(O)(C)C(NC)C(C)OC1OC(C(=C1O)C)=CC(C2=O)=C1NC(O)C1N2C=C(C=CC)C1 RAGFPHFDFVNLCG-UHFFFAOYSA-N 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229940035024 thioglycerol Drugs 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/03—Actinomadura
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77033585A | 1985-08-27 | 1985-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE862280L IE862280L (en) | 1987-02-27 |
| IE59204B1 true IE59204B1 (en) | 1994-01-26 |
Family
ID=25088206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE228086A IE59204B1 (en) | 1985-08-27 | 1986-08-26 | Antibiotics |
Country Status (26)
| Country | Link |
|---|---|
| JP (2) | JPH0733393B2 (fi) |
| KR (1) | KR920010226B1 (fi) |
| AT (1) | AT392971B (fi) |
| AU (1) | AU604464B2 (fi) |
| BE (1) | BE905332A (fi) |
| CA (1) | CA1307256C (fi) |
| CH (1) | CH668598A5 (fi) |
| CY (1) | CY1676A (fi) |
| DE (1) | DE3629052C2 (fi) |
| DK (1) | DK170671B1 (fi) |
| ES (1) | ES2002728A6 (fi) |
| FI (1) | FI83422C (fi) |
| FR (1) | FR2586686B1 (fi) |
| GB (1) | GB2179649A (fi) |
| GR (1) | GR862160B (fi) |
| HK (1) | HK793A (fi) |
| HU (1) | HU197915B (fi) |
| IE (1) | IE59204B1 (fi) |
| IL (1) | IL79519A0 (fi) |
| IT (1) | IT1229176B (fi) |
| LU (1) | LU86562A1 (fi) |
| NL (1) | NL8602165A (fi) |
| PT (1) | PT83261B (fi) |
| SE (2) | SE469632B (fi) |
| SG (1) | SG109692G (fi) |
| ZA (1) | ZA865796B (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE219096T1 (de) * | 1987-01-30 | 2002-06-15 | American Cyanamid Co | Dihydroderivate der antibiotika vom typ ll-e33288 |
| US4916065A (en) * | 1988-06-10 | 1990-04-10 | Bristol-Myers Company | BU-3420T Antitumor antibiotic |
| US5028536A (en) * | 1989-03-15 | 1991-07-02 | Bristol-Myers Squibb Company | Antitumor antibiotic BMY-41339 |
| US5086045A (en) * | 1989-03-15 | 1992-02-04 | Bristol-Myers Squibb Company | Antitumor antibiotic |
| CA2027601A1 (en) * | 1989-11-06 | 1991-05-07 | Koko Sugawara | Antitumor antibiotic bu-3983t |
| CA2039789A1 (en) * | 1990-04-27 | 1991-10-28 | Samuel J. Danishefsky | Calicheamicinone, derivatives and analogs thereof and methods of making the same |
| US5116845A (en) * | 1990-05-04 | 1992-05-26 | Bristol-Myers Company | BU-3420T antitumor antibiotic |
| US5264586A (en) * | 1991-07-17 | 1993-11-23 | The Scripps Research Institute | Analogs of calicheamicin gamma1I, method of making and using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3148023A1 (de) * | 1981-12-04 | 1983-06-09 | Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer | Heizungskessel fuer heisse rauchgase |
| US4578271A (en) * | 1982-05-24 | 1986-03-25 | Fujisawa Pharmaceutical Co., Ltd. | Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions |
| NZ208013A (en) * | 1983-05-16 | 1987-07-31 | Bristol Myers Co | Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora |
| JPS606194A (ja) * | 1983-06-23 | 1985-01-12 | Meiji Seika Kaisha Ltd | 新規抗生物質ｓｆ−２２８８及びその製造法 |
| US4530835A (en) * | 1983-07-08 | 1985-07-23 | Warner-Lambert Company | CL-1577 Antibiotic compounds and their production |
-
1986
- 1986-07-25 IL IL79519A patent/IL79519A0/xx not_active IP Right Cessation
- 1986-08-01 ZA ZA865796A patent/ZA865796B/xx unknown
- 1986-08-15 CA CA000516111A patent/CA1307256C/en not_active Expired - Fee Related
- 1986-08-19 GB GB08620118A patent/GB2179649A/en active Granted
- 1986-08-20 GR GR862160A patent/GR862160B/el unknown
- 1986-08-22 FI FI863405A patent/FI83422C/fi not_active IP Right Cessation
- 1986-08-22 AU AU61751/86A patent/AU604464B2/en not_active Ceased
- 1986-08-26 LU LU86562A patent/LU86562A1/fr unknown
- 1986-08-26 DK DK406086A patent/DK170671B1/da not_active IP Right Cessation
- 1986-08-26 FR FR868612085A patent/FR2586686B1/fr not_active Expired - Fee Related
- 1986-08-26 ES ES8601355A patent/ES2002728A6/es not_active Expired
- 1986-08-26 CH CH3417/86A patent/CH668598A5/de not_active IP Right Cessation
- 1986-08-26 KR KR1019860007092A patent/KR920010226B1/ko not_active IP Right Cessation
- 1986-08-26 IE IE228086A patent/IE59204B1/en not_active IP Right Cessation
- 1986-08-26 IT IT8621527A patent/IT1229176B/it active
- 1986-08-26 NL NL8602165A patent/NL8602165A/nl not_active Application Discontinuation
- 1986-08-26 BE BE0/217084A patent/BE905332A/fr not_active IP Right Cessation
- 1986-08-26 SE SE8603597A patent/SE469632B/sv not_active IP Right Cessation
- 1986-08-27 PT PT83261A patent/PT83261B/pt unknown
- 1986-08-27 AT AT2317/86A patent/AT392971B/de not_active IP Right Cessation
- 1986-08-27 DE DE3629052A patent/DE3629052C2/de not_active Expired - Fee Related
- 1986-08-27 HU HU863709A patent/HU197915B/hu not_active IP Right Cessation
- 1986-08-27 JP JP61201199A patent/JPH0733393B2/ja not_active Expired - Lifetime
-
1992
- 1992-02-13 SE SE9200428A patent/SE9200428L/xx not_active Application Discontinuation
- 1992-10-16 SG SG1096/92A patent/SG109692G/en unknown
-
1993
- 1993-01-07 HK HK7/93A patent/HK793A/xx not_active IP Right Cessation
- 1993-10-10 CY CY1676A patent/CY1676A/xx unknown
-
1994
- 1994-08-19 JP JP6195156A patent/JPH07233186A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |