DK168512B1 - Terapeutiske præparater til brug ved fotodiagnose og fototerapi - Google Patents

Terapeutiske præparater til brug ved fotodiagnose og fototerapi Download PDF

Info

Publication number
DK168512B1
DK168512B1 DK197386A DK197386A DK168512B1 DK 168512 B1 DK168512 B1 DK 168512B1 DK 197386 A DK197386 A DK 197386A DK 197386 A DK197386 A DK 197386A DK 168512 B1 DK168512 B1 DK 168512B1
Authority
DK
Denmark
Prior art keywords
chlorine
mono
alanyl
oak
mesochlorin
Prior art date
Application number
DK197386A
Other languages
Danish (da)
English (en)
Other versions
DK197386D0 (da
DK197386A (da
Inventor
Jerry C Bommer
Bruce F Burnham
Original Assignee
Nippon Petrochemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Petrochemicals Co Ltd filed Critical Nippon Petrochemicals Co Ltd
Publication of DK197386D0 publication Critical patent/DK197386D0/da
Publication of DK197386A publication Critical patent/DK197386A/da
Application granted granted Critical
Publication of DK168512B1 publication Critical patent/DK168512B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK197386A 1985-04-30 1986-04-30 Terapeutiske præparater til brug ved fotodiagnose og fototerapi DK168512B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/728,752 US4977177A (en) 1985-04-30 1985-04-30 Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
US72875285 1985-04-30

Publications (3)

Publication Number Publication Date
DK197386D0 DK197386D0 (da) 1986-04-30
DK197386A DK197386A (da) 1986-10-31
DK168512B1 true DK168512B1 (da) 1994-04-11

Family

ID=24928150

Family Applications (1)

Application Number Title Priority Date Filing Date
DK197386A DK168512B1 (da) 1985-04-30 1986-04-30 Terapeutiske præparater til brug ved fotodiagnose og fototerapi

Country Status (9)

Country Link
US (1) US4977177A (de)
EP (1) EP0213272B1 (de)
JP (1) JPH0794392B2 (de)
AT (1) ATE80297T1 (de)
AU (1) AU583373B2 (de)
CA (1) CA1314042C (de)
DE (1) DE3686683T2 (de)
DK (1) DK168512B1 (de)
NO (1) NO169292C (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8522670D0 (en) * 1985-09-13 1985-10-16 Efamol Ltd Drug treatments
US6184232B1 (en) 1986-12-02 2001-02-06 University Of Florida Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
US5004811A (en) * 1987-12-24 1991-04-02 Nippon Petrochemicals Company, Ltd. Tetrapyrrole aminocarboxylic acids
DE3827940A1 (de) * 1988-08-13 1990-03-01 Schering Ag 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
CN1039283C (zh) * 1988-12-12 1998-07-29 Fmc公司 卟啉的应用
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5567687A (en) * 1989-03-06 1996-10-22 University Of Texas Texaphyrins and uses thereof
US5162509A (en) * 1989-03-06 1992-11-10 Board Of Regents, The University Of Texas System Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5599923A (en) * 1989-03-06 1997-02-04 Board Of Regents, University Of Tx Texaphyrin metal complexes having improved functionalization
US5252720A (en) * 1989-03-06 1993-10-12 Board Of Regents, The University Of Texas System Metal complexes of water soluble texaphyrins
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5234940A (en) * 1989-07-28 1993-08-10 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5955490A (en) * 1989-07-28 1999-09-21 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US6710066B2 (en) * 1989-07-28 2004-03-23 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5079262A (en) * 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US20020058008A1 (en) * 1989-07-28 2002-05-16 Kennedy James C. Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US4997639A (en) * 1989-11-27 1991-03-05 Nippon Petrochemicals Company, Limited Method for detecting cholesterol deposited in bodies of mammals
US5594136A (en) * 1989-12-21 1997-01-14 Pharmacyclics, Inc. Texaphyrin solid supports and devices
US5587394A (en) * 1991-03-28 1996-12-24 The University Of Toledo Production and use of diels alder adducts of vinyl porphyrins, of metal complexes thereof, and of compositions containing such adducts and complexes
JP3154742B2 (ja) * 1991-04-30 2001-04-09 日本石油化学株式会社 哺乳類の動脈硬化症治療剤
US20040110819A1 (en) * 1991-10-28 2004-06-10 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
WO1993008847A1 (en) * 1991-10-31 1993-05-13 Ctm Associates, Inc. Biological stain composition, method of preparation and method of use for delineation of epitheleal cancer
US5565552A (en) * 1992-01-21 1996-10-15 Pharmacyclics, Inc. Method of expanded porphyrin-oligonucleotide conjugate synthesis
US5763172A (en) * 1992-01-21 1998-06-09 Board Of Regents, The University Of Texas System Method of phosphate ester hydrolysis
US5888997A (en) * 1994-04-14 1999-03-30 Pharmacyclics, Inc. Radiation sensitization using texaphyrins
US5595726A (en) * 1992-01-21 1997-01-21 Pharmacyclics, Inc. Chromophore probe for detection of nucleic acid
US5607924A (en) * 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
US5330741A (en) * 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
US6417003B1 (en) * 1993-01-14 2002-07-09 Zila, Inc. Method and kit for epithelial cancer screening
AU696368B2 (en) * 1993-01-14 1998-09-10 Zila Biotechnology, Inc. Method and kit for epithelial cancer screening
JP3565442B2 (ja) * 1993-04-22 2004-09-15 新日本石油化学株式会社 哺乳類の関節炎の診断剤および／または治療剤
US5798491A (en) * 1993-06-09 1998-08-25 Board Of Regents, The University Of Texas System Multi-mechanistic chemical cleavage using certain metal complexes
US5539100A (en) * 1993-07-01 1996-07-23 The United States Of America As Represented By The United States Department Of Energy Organic solid state switches incorporating porphyrin compounds and method for producing organic solid state optical switches
US5492924A (en) * 1993-09-24 1996-02-20 Fox Chase Cancer Center Phorbine derivatives and their use in the diagnosis and therapy of cancer
US5510390A (en) 1994-01-28 1996-04-23 University Of Florida Research Foundation, Inc. Anti-hypertensive composition and methods of treatment
US5969111A (en) * 1994-04-14 1999-10-19 Board Of Regents, The University Of Texas System Texaphyrins substituted with imidazole are provided
US5837866A (en) * 1994-09-21 1998-11-17 Board Of Regents, The University Of Texas Phosphoramidite derivatives of macrocycles
US5633354A (en) * 1994-09-21 1997-05-27 Pharmacyclics, Inc. Phosphoramidite derivatives of texaphyrins
US5669916A (en) * 1994-09-28 1997-09-23 The General Hospital Corporation Method of hair removal
US5756726A (en) * 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
US5714328A (en) * 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
WO2000000204A1 (en) 1997-02-14 2000-01-06 Miravant Pharmaceuticals, Inc. Indium photosensitizers for pdt
US6316215B1 (en) 1999-12-27 2001-11-13 Edwin L. Adair Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods
IL126953A0 (en) 1998-11-08 1999-09-22 Yeda Res & Dev Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives
CN1090633C (zh) * 1999-10-28 2002-09-11 许德余 叶绿素a降解产物金属络合物、其制备方法及抗胃溃疡药物
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6190877B1 (en) 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
RU2183956C1 (ru) 2001-03-30 2002-06-27 Общество с ограниченной ответственностью "РАДА-ФАРМА" Фотосенсибилизатор и способ его получения
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
US7353532B2 (en) * 2002-08-30 2008-04-01 International Business Machines Corporation Secure system and method for enforcement of privacy policy and protection of confidentiality
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
US10376711B2 (en) 2003-03-14 2019-08-13 Light Sciences Oncology Inc. Light generating guide wire for intravascular use
CN2885311Y (zh) 2006-01-18 2007-04-04 郑成福 经尿道光动力疗法前列腺治疗仪
WO2004110438A1 (fr) * 2003-06-17 2004-12-23 Peter Timofeevich Petrov Agent de diagnostic et de therapie photodynamiques de maladies oncologiques
WO2007025244A2 (en) 2005-08-25 2007-03-01 Houle Philip R Treatment systems for delivery of sensitizer solutions
WO2007103427A2 (en) * 2006-03-06 2007-09-13 Wang Xiang H Medical use of bilirubin and its structural analogues
US8198312B2 (en) * 2006-06-30 2012-06-12 Light Sciences Oncology, Inc. Compositions and methods of making a photoactive agent
KR100808630B1 (ko) * 2006-12-28 2008-02-29 광주과학기술원 클로린 화합물을 포함하는 경구투여용 항종양 조성물
WO2014071138A1 (en) 2012-11-02 2014-05-08 Lewis Thomas J Disease detection and treatment through activation of compounds using external energy
EP3923729A4 (de) * 2019-02-15 2022-11-23 Suncor Energy Inc. Verwendung von protoporphyrin-ix-derivaten zur verbesserung der gesundheit von pflanzen

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819644B2 (ja) 1975-03-13 1983-04-19 ウェルファイド株式会社 スイチユウボウオザイ
US4393071A (en) * 1975-03-17 1983-07-12 Naoharu Fujii Method of treating gastric, mammary, lung and uterus tumors
JPS53109929A (en) * 1977-03-04 1978-09-26 Nippon Oil Co Ltd Medicin for malignant tumor
JPS5810388B2 (ja) * 1980-11-19 1983-02-25 森六株式会社 近位塩基型鉄ポルフィリン錯体
JPS58981A (ja) * 1981-06-26 1983-01-06 Tama Seikagaku Kk 水溶性ポルフイリン誘導体
JPS58201791A (ja) * 1982-05-19 1983-11-24 Katsuo Unno ヘマトポルフイリン誘導体
JPS60500132A (ja) * 1982-09-27 1985-01-31 ヘルス・リサーチ・インコーポレーテッド 腫瘍の診断および治療のための精製されたヘマトポルフイリン誘導体ならびにその方法
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
JPS60126291A (ja) * 1983-03-14 1985-07-05 Koichi Shiyudo ポルフイリン誘導体
EP0142732B1 (de) 1983-10-24 1990-01-24 Toyo Hakka Kogyo Kabushiki Kaisha Pheophorbidderivate und diese enthaltende pharmazeutische Mittel
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4693885A (en) * 1984-07-18 1987-09-15 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4624666A (en) * 1984-07-20 1986-11-25 Personal Products Company Channeled napkin with dry cover
SE455172B (sv) * 1984-10-24 1988-06-27 Seco Tools Ab Skerverktyg med ett elastiskt fjedrande element for fastspenning av ett sker
JPH0764728B2 (ja) * 1985-04-30 1995-07-12 日本石油化学株式会社 新規なテトラピロ−ル医薬用組成物
US4656186A (en) * 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents

Also Published As

Publication number Publication date
NO861722L (no) 1986-10-31
EP0213272A3 (en) 1988-05-04
DE3686683T2 (de) 1993-03-11
AU583373B2 (en) 1989-04-27
EP0213272B1 (de) 1992-09-09
ATE80297T1 (de) 1992-09-15
DK197386D0 (da) 1986-04-30
JPS625924A (ja) 1987-01-12
JPH0794392B2 (ja) 1995-10-11
US4977177A (en) 1990-12-11
NO169292B (no) 1992-02-24
EP0213272A2 (de) 1987-03-11
DE3686683D1 (en) 1992-10-15
CA1314042C (en) 1993-03-02
AU5688986A (en) 1986-11-06
DK197386A (da) 1986-10-31
NO169292C (no) 1992-06-03

Similar Documents

Publication Publication Date Title
DK168512B1 (da) Terapeutiske præparater til brug ved fotodiagnose og fototerapi
DK168296B1 (da) Fluorescerende mono-, di- eller polyamider af en amino-monocarboxylsyre og en tetrapyrrolforbindelse samt anvendelse af disse til fremstilling af et farmaceutisk præparat til fotodiagnose og/eller fototerapi af tumorer
DK167769B1 (da) Fluorescerende mono-, di- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende tre carboxylgrupper samt fremgangsmaade til fremstilling deraf
EP0168832B1 (de) Pharmazeutische Zubereitung enthaltend eine Tetrahydropyrrolverbindung als aktiven Bestandteil und Verfahren zur Herstellung dieser Tetrapyrrolverbindung
EP0322795B1 (de) Tetrapyrrolaminocarbonsäuren
CA2121716C (en) Method and medical agent for diagnosis of arthritis
DK168690B1 (da) Farmaceutiske præparater til detektion og/eller behandling af pattedyrtumorer
JP2001507369A (ja) 光活性薬剤としてのモノヒドロベンゾポルフィリン誘導体のエチレングリコールエステル
HU224553B1 (hu) Átészterezési eljárás klorofill- és bakterioklorofill C-133, C-173 diészterek előállítására
SK287784B6 (sk) Fotosenzitizér a spôsob jeho prípravy
US5066274A (en) Tetrapyrrole therapeutic agents
JP5290142B2 (ja) 新規な糖連結クロリン誘導体
US20080139804A1 (en) Photosensitive Compounds
JPH02149519A (ja) 波長特異的細胞毒性試薬

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired