DK168512B1 - Terapeutiske præparater til brug ved fotodiagnose og fototerapi - Google Patents
Terapeutiske præparater til brug ved fotodiagnose og fototerapi Download PDFInfo
- Publication number
- DK168512B1 DK168512B1 DK197386A DK197386A DK168512B1 DK 168512 B1 DK168512 B1 DK 168512B1 DK 197386 A DK197386 A DK 197386A DK 197386 A DK197386 A DK 197386A DK 168512 B1 DK168512 B1 DK 168512B1
- Authority
- DK
- Denmark
- Prior art keywords
- chlorine
- mono
- alanyl
- oak
- mesochlorin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72875285 | 1985-04-30 | ||
US06/728,752 US4977177A (en) | 1985-04-30 | 1985-04-30 | Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents |
Publications (3)
Publication Number | Publication Date |
---|---|
DK197386D0 DK197386D0 (da) | 1986-04-30 |
DK197386A DK197386A (da) | 1986-10-31 |
DK168512B1 true DK168512B1 (da) | 1994-04-11 |
Family
ID=24928150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK197386A DK168512B1 (da) | 1985-04-30 | 1986-04-30 | Terapeutiske præparater til brug ved fotodiagnose og fototerapi |
Country Status (9)
Country | Link |
---|---|
US (1) | US4977177A (de) |
EP (1) | EP0213272B1 (de) |
JP (1) | JPH0794392B2 (de) |
AT (1) | ATE80297T1 (de) |
AU (1) | AU583373B2 (de) |
CA (1) | CA1314042C (de) |
DE (1) | DE3686683T2 (de) |
DK (1) | DK168512B1 (de) |
NO (1) | NO169292C (de) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8522670D0 (en) * | 1985-09-13 | 1985-10-16 | Efamol Ltd | Drug treatments |
US6184232B1 (en) | 1986-12-02 | 2001-02-06 | University Of Florida | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment |
US5004811A (en) * | 1987-12-24 | 1991-04-02 | Nippon Petrochemicals Company, Ltd. | Tetrapyrrole aminocarboxylic acids |
DE3827940A1 (de) * | 1988-08-13 | 1990-03-01 | Schering Ag | 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
CN1039283C (zh) * | 1988-12-12 | 1998-07-29 | Fmc公司 | 卟啉的应用 |
US5162509A (en) * | 1989-03-06 | 1992-11-10 | Board Of Regents, The University Of Texas System | Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
US5559207A (en) * | 1989-03-06 | 1996-09-24 | Board Of Regents, University Of Texas | Texaphyrin metal complex mediated ester hydrolysis |
US4935498A (en) * | 1989-03-06 | 1990-06-19 | Board Of Regents, The University Of Texas System | Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
US5599923A (en) * | 1989-03-06 | 1997-02-04 | Board Of Regents, University Of Tx | Texaphyrin metal complexes having improved functionalization |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5252720A (en) * | 1989-03-06 | 1993-10-12 | Board Of Regents, The University Of Texas System | Metal complexes of water soluble texaphyrins |
US5567687A (en) * | 1989-03-06 | 1996-10-22 | University Of Texas | Texaphyrins and uses thereof |
US5079262A (en) * | 1989-07-28 | 1992-01-07 | Queen's University At Kingston | Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid |
US5234940A (en) * | 1989-07-28 | 1993-08-10 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
US20020058008A1 (en) * | 1989-07-28 | 2002-05-16 | Kennedy James C. | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US6710066B2 (en) | 1989-07-28 | 2004-03-23 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US5955490A (en) * | 1989-07-28 | 1999-09-21 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US4997639A (en) * | 1989-11-27 | 1991-03-05 | Nippon Petrochemicals Company, Limited | Method for detecting cholesterol deposited in bodies of mammals |
US5594136A (en) * | 1989-12-21 | 1997-01-14 | Pharmacyclics, Inc. | Texaphyrin solid supports and devices |
US5587394A (en) * | 1991-03-28 | 1996-12-24 | The University Of Toledo | Production and use of diels alder adducts of vinyl porphyrins, of metal complexes thereof, and of compositions containing such adducts and complexes |
JP3154742B2 (ja) * | 1991-04-30 | 2001-04-09 | 日本石油化学株式会社 | 哺乳類の動脈硬化症治療剤 |
US20040110819A1 (en) * | 1991-10-28 | 2004-06-10 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
KR100242727B1 (ko) * | 1991-10-31 | 2000-03-02 | 에드윈 포머란츠 | 상피암의 현장윤곽묘사를위한생물학적염색조성물,이들의제조방법및사용방법 |
US5607924A (en) * | 1992-01-21 | 1997-03-04 | Pharmacyclics, Inc. | DNA photocleavage using texaphyrins |
US5763172A (en) * | 1992-01-21 | 1998-06-09 | Board Of Regents, The University Of Texas System | Method of phosphate ester hydrolysis |
US5595726A (en) * | 1992-01-21 | 1997-01-21 | Pharmacyclics, Inc. | Chromophore probe for detection of nucleic acid |
US5565552A (en) * | 1992-01-21 | 1996-10-15 | Pharmacyclics, Inc. | Method of expanded porphyrin-oligonucleotide conjugate synthesis |
US5888997A (en) * | 1994-04-14 | 1999-03-30 | Pharmacyclics, Inc. | Radiation sensitization using texaphyrins |
US5330741A (en) * | 1992-02-24 | 1994-07-19 | The Regents Of The University Of California | Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors |
IL102645A (en) * | 1992-07-26 | 1998-02-22 | Yeda Res & Dev | Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them |
US6417003B1 (en) * | 1993-01-14 | 2002-07-09 | Zila, Inc. | Method and kit for epithelial cancer screening |
EP0636246A1 (de) * | 1993-01-14 | 1995-02-01 | Zila Inc. | Verfahren und testsatz zum nachweis von epithelkrebs |
JP3565442B2 (ja) * | 1993-04-22 | 2004-09-15 | 新日本石油化学株式会社 | 哺乳類の関節炎の診断剤および/または治療剤 |
US5798491A (en) * | 1993-06-09 | 1998-08-25 | Board Of Regents, The University Of Texas System | Multi-mechanistic chemical cleavage using certain metal complexes |
US5539100A (en) * | 1993-07-01 | 1996-07-23 | The United States Of America As Represented By The United States Department Of Energy | Organic solid state switches incorporating porphyrin compounds and method for producing organic solid state optical switches |
US5492924A (en) * | 1993-09-24 | 1996-02-20 | Fox Chase Cancer Center | Phorbine derivatives and their use in the diagnosis and therapy of cancer |
US5510390A (en) * | 1994-01-28 | 1996-04-23 | University Of Florida Research Foundation, Inc. | Anti-hypertensive composition and methods of treatment |
US5969111A (en) * | 1994-04-14 | 1999-10-19 | Board Of Regents, The University Of Texas System | Texaphyrins substituted with imidazole are provided |
US5633354A (en) * | 1994-09-21 | 1997-05-27 | Pharmacyclics, Inc. | Phosphoramidite derivatives of texaphyrins |
US5837866A (en) * | 1994-09-21 | 1998-11-17 | Board Of Regents, The University Of Texas | Phosphoramidite derivatives of macrocycles |
US5669916A (en) * | 1994-09-28 | 1997-09-23 | The General Hospital Corporation | Method of hair removal |
US5756726A (en) * | 1995-06-02 | 1998-05-26 | Pharmacyclics, Inc. | Methods of producing singlet oxygen using compounds having improved functionalization |
US5714328A (en) * | 1995-06-07 | 1998-02-03 | Board Of Regents, The University Of Texas System | RNA photocleavage using texaphyrins |
EP1091742A4 (de) | 1997-02-14 | 2007-05-30 | Miravant Pharm Inc | Indium photosensibilisatoren zur pdt |
US6316215B1 (en) | 1999-12-27 | 2001-11-13 | Edwin L. Adair | Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods |
IL126953A0 (en) | 1998-11-08 | 1999-09-22 | Yeda Res & Dev | Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives |
CN1090633C (zh) * | 1999-10-28 | 2002-09-11 | 许德余 | 叶绿素a降解产物金属络合物、其制备方法及抗胃溃疡药物 |
US6750037B2 (en) | 1999-12-27 | 2004-06-15 | Edwin L. Adair | Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques |
US6984498B2 (en) * | 1999-12-27 | 2006-01-10 | Adair Edwin L | Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques |
US6190877B1 (en) | 1999-12-27 | 2001-02-20 | Edwin L. Adair | Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques |
RU2183956C1 (ru) | 2001-03-30 | 2002-06-27 | Общество с ограниченной ответственностью "РАДА-ФАРМА" | Фотосенсибилизатор и способ его получения |
DE60307545T2 (de) * | 2002-06-21 | 2007-10-04 | Adair, Edwin L., Castle Pines Village | Anwendung von Metalloporphyrinen zur Behandlung von Arteriosklerose |
US7353532B2 (en) * | 2002-08-30 | 2008-04-01 | International Business Machines Corporation | Secure system and method for enforcement of privacy policy and protection of confidentiality |
IL152900A0 (en) * | 2002-11-17 | 2003-06-24 | Yeda Res & Dev | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
CN2885311Y (zh) | 2006-01-18 | 2007-04-04 | 郑成福 | 经尿道光动力疗法前列腺治疗仪 |
US10376711B2 (en) | 2003-03-14 | 2019-08-13 | Light Sciences Oncology Inc. | Light generating guide wire for intravascular use |
WO2004110438A1 (fr) * | 2003-06-17 | 2004-12-23 | Peter Timofeevich Petrov | Agent de diagnostic et de therapie photodynamiques de maladies oncologiques |
CA2632183A1 (en) | 2005-08-25 | 2007-03-01 | Philip R. Houle | Treatment systems for delivery of sensitizer solutions |
WO2007103427A2 (en) * | 2006-03-06 | 2007-09-13 | Wang Xiang H | Medical use of bilirubin and its structural analogues |
JP5323693B2 (ja) * | 2006-06-30 | 2013-10-23 | ライト、サイエンシーズ、オンコロジー、インコーポレイテッド | 光活性剤としてのクロリンe6誘導体の組成物およびクロリンe6誘導体を製造する方法 |
KR100808630B1 (ko) * | 2006-12-28 | 2008-02-29 | 광주과학기술원 | 클로린 화합물을 포함하는 경구투여용 항종양 조성물 |
WO2014071138A1 (en) | 2012-11-02 | 2014-05-08 | Lewis Thomas J | Disease detection and treatment through activation of compounds using external energy |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5819644B2 (ja) | 1975-03-13 | 1983-04-19 | ウェルファイド株式会社 | スイチユウボウオザイ |
US4393071A (en) * | 1975-03-17 | 1983-07-12 | Naoharu Fujii | Method of treating gastric, mammary, lung and uterus tumors |
JPS53109929A (en) * | 1977-03-04 | 1978-09-26 | Nippon Oil Co Ltd | Medicin for malignant tumor |
JPS5810388B2 (ja) * | 1980-11-19 | 1983-02-25 | 森六株式会社 | 近位塩基型鉄ポルフィリン錯体 |
JPS58981A (ja) * | 1981-06-26 | 1983-01-06 | Tama Seikagaku Kk | 水溶性ポルフイリン誘導体 |
JPS58201791A (ja) * | 1982-05-19 | 1983-11-24 | Katsuo Unno | ヘマトポルフイリン誘導体 |
US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
ATE53204T1 (de) * | 1982-09-27 | 1990-06-15 | Photofrin Medical Inc | Gereinigte hematoporphyrinabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren. |
JPS60126291A (ja) * | 1983-03-14 | 1985-07-05 | Koichi Shiyudo | ポルフイリン誘導体 |
EP0142732B1 (de) | 1983-10-24 | 1990-01-24 | Toyo Hakka Kogyo Kabushiki Kaisha | Pheophorbidderivate und diese enthaltende pharmazeutische Mittel |
US4675338A (en) * | 1984-07-18 | 1987-06-23 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
US4693885A (en) * | 1984-07-18 | 1987-09-15 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
US4624666A (en) * | 1984-07-20 | 1986-11-25 | Personal Products Company | Channeled napkin with dry cover |
SE455172B (sv) * | 1984-10-24 | 1988-06-27 | Seco Tools Ab | Skerverktyg med ett elastiskt fjedrande element for fastspenning av ett sker |
JPH0764728B2 (ja) * | 1985-04-30 | 1995-07-12 | 日本石油化学株式会社 | 新規なテトラピロ−ル医薬用組成物 |
US4656186A (en) * | 1985-04-30 | 1987-04-07 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
-
1985
- 1985-04-30 US US06/728,752 patent/US4977177A/en not_active Expired - Lifetime
-
1986
- 1986-04-30 AT AT86105955T patent/ATE80297T1/de not_active IP Right Cessation
- 1986-04-30 EP EP86105955A patent/EP0213272B1/de not_active Expired - Lifetime
- 1986-04-30 NO NO861722A patent/NO169292C/no not_active IP Right Cessation
- 1986-04-30 AU AU56889/86A patent/AU583373B2/en not_active Expired
- 1986-04-30 DK DK197386A patent/DK168512B1/da not_active IP Right Cessation
- 1986-04-30 DE DE8686105955T patent/DE3686683T2/de not_active Expired - Lifetime
- 1986-04-30 CA CA000507943A patent/CA1314042C/en not_active Expired - Lifetime
- 1986-04-30 JP JP61100301A patent/JPH0794392B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK197386D0 (da) | 1986-04-30 |
ATE80297T1 (de) | 1992-09-15 |
EP0213272B1 (de) | 1992-09-09 |
JPH0794392B2 (ja) | 1995-10-11 |
NO169292C (no) | 1992-06-03 |
EP0213272A2 (de) | 1987-03-11 |
NO861722L (no) | 1986-10-31 |
DK197386A (da) | 1986-10-31 |
DE3686683D1 (en) | 1992-10-15 |
US4977177A (en) | 1990-12-11 |
CA1314042C (en) | 1993-03-02 |
EP0213272A3 (en) | 1988-05-04 |
NO169292B (no) | 1992-02-24 |
AU5688986A (en) | 1986-11-06 |
AU583373B2 (en) | 1989-04-27 |
JPS625924A (ja) | 1987-01-12 |
DE3686683T2 (de) | 1993-03-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK168512B1 (da) | Terapeutiske præparater til brug ved fotodiagnose og fototerapi | |
DK168296B1 (da) | Fluorescerende mono-, di- eller polyamider af en amino-monocarboxylsyre og en tetrapyrrolforbindelse samt anvendelse af disse til fremstilling af et farmaceutisk præparat til fotodiagnose og/eller fototerapi af tumorer | |
DK167769B1 (da) | Fluorescerende mono-, di- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende tre carboxylgrupper samt fremgangsmaade til fremstilling deraf | |
EP0168832B1 (de) | Pharmazeutische Zubereitung enthaltend eine Tetrahydropyrrolverbindung als aktiven Bestandteil und Verfahren zur Herstellung dieser Tetrapyrrolverbindung | |
EP0322795B1 (de) | Tetrapyrrolaminocarbonsäuren | |
CA2121716C (en) | Method and medical agent for diagnosis of arthritis | |
DK168690B1 (da) | Farmaceutiske præparater til detektion og/eller behandling af pattedyrtumorer | |
JP2001507369A (ja) | 光活性薬剤としてのモノヒドロベンゾポルフィリン誘導体のエチレングリコールエステル | |
HU224553B1 (hu) | Átészterezési eljárás klorofill- és bakterioklorofill C-133, C-173 diészterek előállítására | |
SK287784B6 (sk) | Fotosenzitizér a spôsob jeho prípravy | |
US5066274A (en) | Tetrapyrrole therapeutic agents | |
JP5290142B2 (ja) | 新規な糖連結クロリン誘導体 | |
Grin et al. | Novel bacteriochlorophyll-based photosensitizers and their photodynamic activity | |
US20080139804A1 (en) | Photosensitive Compounds | |
JPH02149519A (ja) | 波長特異的細胞毒性試薬 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |