DK162090C - 3-acyl-2-oxindol-1-carboxamid-forbindelser samt 2-oxindol-1-carboxamid-forbindelser til anvendelse som mellemprodukter - Google Patents

3-acyl-2-oxindol-1-carboxamid-forbindelser samt 2-oxindol-1-carboxamid-forbindelser til anvendelse som mellemprodukter

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Publication number
DK162090C
DK162090C DK121385A DK121385A DK162090C DK 162090 C DK162090 C DK 162090C DK 121385 A DK121385 A DK 121385A DK 121385 A DK121385 A DK 121385A DK 162090 C DK162090 C DK 162090C
Authority
DK
Denmark
Prior art keywords
oxindol
intermediates
carboxamide compounds
alkyl
optionally substituted
Prior art date
Application number
DK121385A
Other languages
Danish (da)
English (en)
Other versions
DK162090B (da
DK121385A (da
DK121385D0 (da
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer
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Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK121385D0 publication Critical patent/DK121385D0/da
Publication of DK121385A publication Critical patent/DK121385A/da
Publication of DK162090B publication Critical patent/DK162090B/da
Application granted granted Critical
Publication of DK162090C publication Critical patent/DK162090C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK121385A 1984-03-19 1985-03-18 3-acyl-2-oxindol-1-carboxamid-forbindelser samt 2-oxindol-1-carboxamid-forbindelser til anvendelse som mellemprodukter DK162090C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59065984A 1984-03-19 1984-03-19
US59065984 1984-03-19
US06/684,634 US4556672A (en) 1984-03-19 1984-12-21 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US68463484 1984-12-21

Publications (4)

Publication Number Publication Date
DK121385D0 DK121385D0 (da) 1985-03-18
DK121385A DK121385A (da) 1985-09-20
DK162090B DK162090B (da) 1991-09-16
DK162090C true DK162090C (da) 1992-02-24

Family

ID=27080909

Family Applications (1)

Application Number Title Priority Date Filing Date
DK121385A DK162090C (da) 1984-03-19 1985-03-18 3-acyl-2-oxindol-1-carboxamid-forbindelser samt 2-oxindol-1-carboxamid-forbindelser til anvendelse som mellemprodukter

Country Status (36)

Country Link
US (1) US4556672A (enExample)
EP (1) EP0156603B1 (enExample)
JP (1) JPH04235165A (enExample)
KR (1) KR860001873B1 (enExample)
AT (1) ATE45731T1 (enExample)
AU (1) AU549927B2 (enExample)
BG (1) BG60347B2 (enExample)
CA (2) CA1251441A (enExample)
CS (1) CS249539B2 (enExample)
CY (1) CY1668A (enExample)
DE (1) DE3572481D1 (enExample)
DK (1) DK162090C (enExample)
EG (1) EG17795A (enExample)
ES (1) ES541372A0 (enExample)
FI (2) FI82042C (enExample)
GR (1) GR850668B (enExample)
HK (1) HK78392A (enExample)
HU (1) HU196178B (enExample)
IE (1) IE57743B1 (enExample)
IL (3) IL85130A (enExample)
LV (1) LV5618A3 (enExample)
MA (1) MA20380A1 (enExample)
MY (1) MY101987A (enExample)
NL (1) NL940025I2 (enExample)
NO (1) NO165799C (enExample)
NZ (2) NZ211486A (enExample)
OA (1) OA07966A (enExample)
PH (2) PH21323A (enExample)
PL (1) PL145951B1 (enExample)
PT (1) PT80117B (enExample)
RO (1) RO90952B (enExample)
SI (1) SI8510440A8 (enExample)
SU (1) SU1445556A3 (enExample)
UA (1) UA6343A1 (enExample)
YU (1) YU43870B (enExample)
ZW (1) ZW4785A1 (enExample)

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Also Published As

Publication number Publication date
FI894540A0 (fi) 1989-09-26
DK162090B (da) 1991-09-16
OA07966A (fr) 1987-01-31
KR860001873B1 (ko) 1986-10-24
EP0156603B1 (en) 1989-08-23
FI851069L (fi) 1985-09-20
GR850668B (enExample) 1985-07-16
MA20380A1 (fr) 1985-10-01
ES8603408A1 (es) 1985-12-16
FI82449B (fi) 1990-11-30
IL74631A0 (en) 1985-06-30
CA1251441A (en) 1989-03-21
ATE45731T1 (de) 1989-09-15
IL85130A (en) 1988-07-31
NZ224134A (en) 1988-10-28
YU44085A (en) 1988-02-29
ES541372A0 (es) 1985-12-16
RO90952A (ro) 1987-02-27
LV5618A3 (lv) 1994-05-10
JPH0561269B2 (enExample) 1993-09-06
NZ211486A (en) 1988-10-28
PT80117B (pt) 1987-10-20
NL940025I2 (nl) 2000-01-03
FI894540L (fi) 1989-09-26
DE3572481D1 (en) 1989-09-28
NO851054L (no) 1985-09-20
YU43870B (en) 1989-12-31
PH21323A (en) 1987-09-28
AU4005985A (en) 1985-09-26
PT80117A (en) 1985-04-01
HK78392A (en) 1992-10-23
HUT37398A (en) 1985-12-28
HU196178B (en) 1988-10-28
US4556672A (en) 1985-12-03
PH21470A (en) 1987-10-28
BG60347B2 (bg) 1994-09-30
FI851069A0 (fi) 1985-03-18
IE57743B1 (en) 1993-03-24
SI8510440A8 (sl) 1996-06-30
IL74631A (en) 1988-07-31
DK121385A (da) 1985-09-20
IL85130A0 (en) 1988-06-30
NO165799C (no) 1991-04-10
PL145951B1 (en) 1988-12-31
UA6343A1 (uk) 1994-12-29
IE850684L (en) 1985-09-19
CY1668A (en) 1993-05-14
DK121385D0 (da) 1985-03-18
EP0156603A3 (en) 1986-02-12
NO165799B (no) 1991-01-02
RO90952B (ro) 1987-03-01
PL252434A1 (en) 1985-12-03
MY101987A (en) 1992-02-29
AU549927B2 (en) 1986-02-20
EG17795A (en) 1990-08-30
JPH04235165A (ja) 1992-08-24
FI82449C (fi) 1991-03-11
FI82042C (fi) 1991-01-10
NL940025I1 (nl) 1995-02-01
EP0156603A2 (en) 1985-10-02
ZW4785A1 (en) 1985-06-19
KR850006173A (ko) 1985-10-02
SU1445556A3 (ru) 1988-12-15
CS249539B2 (en) 1987-03-12
CA1288422C (en) 1991-09-03
FI82042B (fi) 1990-09-28

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