ES8603409A1 - Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamida - Google Patents
Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamidaInfo
- Publication number
- ES8603409A1 ES8603409A1 ES541373A ES541373A ES8603409A1 ES 8603409 A1 ES8603409 A1 ES 8603409A1 ES 541373 A ES541373 A ES 541373A ES 541373 A ES541373 A ES 541373A ES 8603409 A1 ES8603409 A1 ES 8603409A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- optionally substituted
- oxindole
- carboxamides
- making
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 2-OXINDOL-1-CARBOXAMIDA, DE FORMULA (I), EN LA QUE X, Y Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE HIDROLISIS DE UN COMPUESTO DE FORMULA (II), EN LA QUE X, Y Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA HIDROLISIS SE EFECTUA POR TRATAMIENTO CON AGUA SOLA O CON DISOLUCION ACUOSA DE UN ACIDO INORGANICO U ORGANICO EN CONCENTRACION ENTRE 1 Y 6 MOLAR, A LA TEMPERATURA DE UN BAÑO DE VAPOR. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS PARA LA SINTESIS DE AGENTES ANALGESICOS Y ANTIINFLAMATORIOS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59066784A | 1984-03-19 | 1984-03-19 | |
| US68488984A | 1984-12-21 | 1984-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES541373A0 ES541373A0 (es) | 1985-12-16 |
| ES8603409A1 true ES8603409A1 (es) | 1985-12-16 |
Family
ID=27080914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541373A Expired ES8603409A1 (es) | 1984-03-19 | 1985-03-18 | Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamida |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP0155828B1 (es) |
| JP (1) | JPH03178963A (es) |
| KR (1) | KR860001874B1 (es) |
| AR (1) | AR247885A1 (es) |
| AU (1) | AU552119B2 (es) |
| BG (1) | BG44203A3 (es) |
| CA (1) | CA1250832A (es) |
| CS (1) | CS250680B2 (es) |
| CY (1) | CY1667A (es) |
| DE (1) | DE3579716D1 (es) |
| DK (2) | DK163662C (es) |
| EG (1) | EG17274A (es) |
| ES (1) | ES8603409A1 (es) |
| FI (1) | FI85265C (es) |
| GR (1) | GR850669B (es) |
| HK (1) | HK75992A (es) |
| HU (1) | HU194825B (es) |
| IE (1) | IE57741B1 (es) |
| IL (1) | IL74630A (es) |
| MA (1) | MA20379A1 (es) |
| NO (1) | NO168639C (es) |
| NZ (1) | NZ211487A (es) |
| OA (1) | OA07967A (es) |
| PH (1) | PH20843A (es) |
| PL (1) | PL145873B1 (es) |
| PT (1) | PT80116B (es) |
| RO (1) | RO90953B (es) |
| YU (1) | YU43869B (es) |
| ZW (1) | ZW4885A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR850310B (es) * | 1984-02-07 | 1985-06-05 | Pfizer | |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| DE3621761A1 (de) * | 1986-06-28 | 1988-01-07 | Bayer Ag | Indolylpropionsaeuren |
| UA25898A1 (uk) * | 1987-02-02 | 1999-02-26 | Пфайзер Інк. | Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| US4952703A (en) * | 1989-05-25 | 1990-08-28 | Pfizer Inc. | Intermediates for making 2-oxindole-1-carboxamides |
| HUP9600855A3 (en) * | 1996-04-03 | 1998-04-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing tenidap |
| JP2004529110A (ja) | 2001-03-06 | 2004-09-24 | アストラゼネカ アクチボラグ | 脈管損傷活性を有するインドール誘導体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3767653A (en) * | 1971-06-28 | 1973-10-23 | Squibb & Sons Inc | Thiazines |
-
1985
- 1985-03-15 CA CA000476599A patent/CA1250832A/en not_active Expired
- 1985-03-15 EP EP85301807A patent/EP0155828B1/en not_active Expired - Lifetime
- 1985-03-15 DE DE8585301807T patent/DE3579716D1/de not_active Expired - Lifetime
- 1985-03-15 GR GR85850669A patent/GR850669B/el not_active IP Right Cessation
- 1985-03-15 IE IE683/85A patent/IE57741B1/en not_active IP Right Cessation
- 1985-03-15 PT PT80116A patent/PT80116B/pt unknown
- 1985-03-17 EG EG173/85A patent/EG17274A/xx active
- 1985-03-18 AU AU40058/85A patent/AU552119B2/en not_active Expired
- 1985-03-18 PL PL1985252433A patent/PL145873B1/pl unknown
- 1985-03-18 MA MA20603A patent/MA20379A1/fr unknown
- 1985-03-18 FI FI851068A patent/FI85265C/fi not_active IP Right Cessation
- 1985-03-18 KR KR1019850001747A patent/KR860001874B1/ko not_active IP Right Cessation
- 1985-03-18 NZ NZ211487A patent/NZ211487A/xx unknown
- 1985-03-18 AR AR85299771A patent/AR247885A1/es active
- 1985-03-18 HU HU85993A patent/HU194825B/hu unknown
- 1985-03-18 ES ES541373A patent/ES8603409A1/es not_active Expired
- 1985-03-18 YU YU428/85A patent/YU43869B/xx unknown
- 1985-03-18 NO NO851059A patent/NO168639C/no not_active IP Right Cessation
- 1985-03-18 DK DK121485A patent/DK163662C/da not_active IP Right Cessation
- 1985-03-18 BG BG8569279A patent/BG44203A3/xx unknown
- 1985-03-18 ZW ZW48/85A patent/ZW4885A1/xx unknown
- 1985-03-18 IL IL74630A patent/IL74630A/xx not_active IP Right Cessation
- 1985-03-19 CS CS851921A patent/CS250680B2/cs unknown
- 1985-03-19 OA OA58542A patent/OA07967A/xx unknown
- 1985-03-19 PH PH32005A patent/PH20843A/en unknown
- 1985-03-19 RO RO118054A patent/RO90953B/ro unknown
-
1990
- 1990-11-30 JP JP2336861A patent/JPH03178963A/ja active Granted
-
1991
- 1991-04-11 DK DK064591A patent/DK165179C/da not_active IP Right Cessation
-
1992
- 1992-10-01 HK HK759/92A patent/HK75992A/xx not_active IP Right Cessation
-
1993
- 1993-05-14 CY CY1667A patent/CY1667A/xx unknown
Also Published As
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|---|---|---|
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20040823 |