DK160868C - Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem - Google Patents

Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem

Info

Publication number
DK160868C
DK160868C DK508283A DK508283A DK160868C DK 160868 C DK160868 C DK 160868C DK 508283 A DK508283 A DK 508283A DK 508283 A DK508283 A DK 508283A DK 160868 C DK160868 C DK 160868C
Authority
DK
Denmark
Prior art keywords
phenenous
radiological
procedures
derivatives
preparing
Prior art date
Application number
DK508283A
Other languages
Danish (da)
English (en)
Other versions
DK160868B (da
DK508283D0 (da
DK508283A (da
Inventor
Per-Egil Hansen
Hugo Holtermann
Knut Wille
Original Assignee
Nyegaard & Co As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As
Publication of DK508283D0 publication Critical patent/DK508283D0/da
Publication of DK508283A publication Critical patent/DK508283A/da
Publication of DK160868B publication Critical patent/DK160868B/da
Application granted granted Critical
Publication of DK160868C publication Critical patent/DK160868C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyesters Or Polycarbonates (AREA)
DK508283A 1982-11-08 1983-11-07 Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem DK160868C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8231796 1982-11-08
GB8231796 1982-11-08

Publications (4)

Publication Number Publication Date
DK508283D0 DK508283D0 (da) 1983-11-07
DK508283A DK508283A (da) 1984-05-09
DK160868B DK160868B (da) 1991-04-29
DK160868C true DK160868C (da) 1991-10-14

Family

ID=10534110

Family Applications (1)

Application Number Title Priority Date Filing Date
DK508283A DK160868C (da) 1982-11-08 1983-11-07 Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem

Country Status (10)

Country Link
US (1) US5349085A (enExample)
EP (1) EP0108638B1 (enExample)
JP (1) JPS59104352A (enExample)
AT (1) ATE20733T1 (enExample)
DE (1) DE3364536D1 (enExample)
DK (1) DK160868C (enExample)
HK (1) HK46791A (enExample)
LU (1) LU88639I2 (enExample)
NL (1) NL950010I1 (enExample)
NO (2) NO161368C (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
GB8919929D0 (en) * 1989-09-04 1989-10-18 Nycomed As Compositions
IT1252180B (it) * 1991-12-10 1995-06-05 Bracco Ind Chimica Spa 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
WO1994022810A1 (es) * 1993-04-01 1994-10-13 Centro Investigacion Justesa Imagen, S.A. Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
US5840967A (en) * 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9720969D0 (en) * 1997-10-02 1997-12-03 Nycomed Imaging As Process
GB9903109D0 (en) * 1999-02-11 1999-04-07 Nycomed Imaging As Process
US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
EP1490090A4 (en) 2002-02-22 2006-09-20 New River Pharmaceuticals Inc SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS
KR100574087B1 (ko) 2004-09-09 2006-04-27 주식회사태준제약 아이오디사놀의 제조방법
JP2008527119A (ja) 2005-01-13 2008-07-24 シンベンション アーゲー 炭素ナノ粒子を含有する複合材料
ES2413761T3 (es) 2005-12-19 2013-07-17 Ge Healthcare As Procedimiento de purificación de iodixanol
DE602007012208D1 (de) 2006-02-15 2011-03-10 Ge Healthcare As Kontrastmittel
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
US7662859B2 (en) 2007-02-16 2010-02-16 Ge Healthcare As Contrast agents
DK2178568T3 (da) 2007-07-12 2014-07-21 Ge Healthcare As Kontrastmidler
EP2200655B1 (en) 2007-10-12 2012-07-18 GE Healthcare AS Contrast agents
US20100221191A1 (en) 2007-10-12 2010-09-02 Duncan George Wynn Contrast agents
US20100209356A1 (en) 2007-10-12 2010-08-19 Duncan George Wynn Contrast agents
US8202511B2 (en) 2007-10-12 2012-06-19 Ge Healthcare As Contrast agents
EP2245003A2 (en) * 2008-02-27 2010-11-03 GE Healthcare AS Contrast agents
WO2009106551A2 (en) * 2008-02-27 2009-09-03 Ge Healthcare As Contrast agents
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
EP2385845A1 (en) * 2009-01-09 2011-11-16 Ge Healthcare As Contrast media compositions
US8962886B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in methanol
US20110021832A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Synthesis of iodixanol in water
US8962887B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol
US7999135B2 (en) 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using ultrasound
US7754920B1 (en) * 2009-07-21 2010-07-13 Ge Healthcare As Solvent reduction in crystallisation of intermediate for non-ionic X-ray contrast agents
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
US20110021821A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous acetylation process in synthesis of non-ionic x-ray contrast agents
US7999134B2 (en) 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using milling
US8969619B2 (en) * 2009-07-21 2015-03-03 Ge Healthcare As Synthesis of iodixanol in propyleneglycol
US7696381B1 (en) * 2009-07-21 2010-04-13 Ge Healthcare As Alternative dimerisation reagents for synthesis of iodixanol
PT2493511E (pt) * 2009-10-29 2013-11-18 Ge Healthcare As Composição de diagnóstico que compreende catiões do plasma com perfil de segurança superior
EP2504298B1 (en) * 2009-11-26 2016-09-21 iMAX Diagnostic Imaging Holding Limited Preparation and purification of iodixanol
CA2801828A1 (en) 2010-07-12 2012-01-19 Ge Healthcare As X-ray imaging at low contrast agent concentrations and/or low dose radiation
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN102816125B (zh) * 2011-06-08 2014-03-26 浙江司太立制药股份有限公司 一种造影剂
CN107982550A (zh) 2012-01-11 2018-05-04 通用电气医疗集团股份有限公司 具有低碘浓度的x-射线成像造影介质和x-射线成像方法
CN104661996A (zh) 2012-09-27 2015-05-27 通用电气医疗集团股份有限公司 Ioforminol的中间体化合物的制备
ES2692071T3 (es) 2012-11-12 2018-11-30 Ge Healthcare As Preparación de intermedios de agentes de contraste para rayos X
CN107249570B (zh) 2014-11-21 2022-08-09 丹麦技术大学 用于局部药物释放的凝胶制剂
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
BR112018073493A2 (pt) 2016-05-20 2019-03-26 Technical University Of Denmark composição de marcador palpável, método e kit de partes para identificar e/ou localizar um tumor não palpável, um tumor palpável com maior precisão e/ou um tecido alvo, e, uso de uma composição de marcador palpável
CN111440084B (zh) * 2019-01-16 2023-01-06 苏州纳微科技股份有限公司 一种碘克沙醇的纯化方法
WO2020249801A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release
CN113121377A (zh) * 2019-12-31 2021-07-16 江苏汉邦科技有限公司 碘克沙醇的纯化方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE344166B (enExample) * 1966-12-13 1972-04-04 Pharmacia Ab
SE315975B (enExample) * 1967-12-28 1969-10-13 Pharmacia Ab
SE315974B (enExample) * 1967-12-28 1969-10-13 Pharmacia Ab
US3763227A (en) * 1967-12-28 1973-10-02 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
US3804892A (en) * 1967-12-28 1974-04-16 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
BR7020080D0 (pt) * 1969-06-27 1973-03-13 Nyegaard & Co As Processo para a preparacao de agentes de contraste para raio x
NL7102816A (enExample) * 1970-03-12 1971-09-14
DD104193A5 (enExample) * 1972-12-22 1974-03-05
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3038853A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus

Also Published As

Publication number Publication date
EP0108638A1 (en) 1984-05-16
ATE20733T1 (de) 1986-08-15
NO834056L (no) 1984-05-09
DE3364536D1 (en) 1986-08-21
JPS59104352A (ja) 1984-06-16
NO1994015I1 (no) 1994-09-05
US5349085A (en) 1994-09-20
NO161368B (no) 1989-05-02
NL950010I2 (nl) 1997-02-03
JPS6355509B2 (enExample) 1988-11-02
DK160868B (da) 1991-04-29
LU88639I2 (fr) 1996-02-01
EP0108638B1 (en) 1986-07-16
NO161368C (no) 1989-08-09
HK46791A (en) 1991-06-21
DK508283D0 (da) 1983-11-07
DK508283A (da) 1984-05-09
NL950010I1 (nl) 1997-02-03

Similar Documents

Publication Publication Date Title
DK160868C (da) Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem
ATE38672T1 (de) 7-oxabicycloheptan aminosubstituierte prostaglandinaehnliche verbindungen.
ES496880A0 (es) Un procedimiento para la preparacion de derivados de benzofurano.
ATE41772T1 (de) Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
GB2046258B (en) N,n'bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-l-gulonamido)isophthalamide and radiological compositions containing same
DK162045C (da) Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
JPS5422304A (en) Preparation of epoxdes
IL60323A0 (en) Pseudotrisaccharide compounds,their preparation and their medicinal use
IT8021166A0 (it) Semiacetali doppi ciclici dicomposti enediolici, composizioni e procedimenti per la loro preparazione.
DK455487D0 (da) 13alfa-alkylgonan-delta9(11)-5,10-epoxider og fremgangsmaade til fremstilling deraf
JPS5411631A (en) Test signal generator
JPS51142088A (en) Aminocyclodextrin derivatives and their prepapation.
DK535082A (da) Diaza-3,7a-cyclohepten(j,k)fluorener og fremgangsmaade til fremstilling deraf
ES8501734A1 (es) Un procedimiento para preparar derivados de cicloalquenilo
JPS545903A (en) Preparation of 4-aminomethyl-1,8-diaminooctane
JPS5217842A (en) Device for fabricating sound hologram
JPS548803A (en) Supporter for stator coil end
JPS5319721A (en) Correcting unit of bar-code signal
JPS5276287A (en) Prparation of oil adsorbent
JPS5318574A (en) Preparation of chromone derivatives
JPS53108711A (en) Split-coding system for facismile signal
JPS5283632A (en) Novel 16-alkyl-20-alkoxy prostadienoic acid derivative
JPS521295A (en) Control device of nuclear reactor
JPS52139006A (en) Synthesis of 3-methylbutanol-1
JPS5318575A (en) Preparation of chromone derivatives

Legal Events

Date Code Title Description
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1995 00006, 950504

CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1995 00006, 950504, EXPIRES: 20080205

PUP Patent expired