NL950010I1 - R¦ntgencontrastmiddelen. - Google Patents

R¦ntgencontrastmiddelen.

Info

Publication number
NL950010I1
NL950010I1 NL950010C NL950010C NL950010I1 NL 950010 I1 NL950010 I1 NL 950010I1 NL 950010 C NL950010 C NL 950010C NL 950010 C NL950010 C NL 950010C NL 950010 I1 NL950010 I1 NL 950010I1
Authority
NL
Netherlands
Prior art keywords
ch2ch
group
contrast media
ray contrast
ch2oh
Prior art date
Application number
NL950010C
Other languages
English (en)
Dutch (nl)
Other versions
NL950010I2 (nl
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NL950010I2 publication Critical patent/NL950010I2/nl
Publication of NL950010I1 publication Critical patent/NL950010I1/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicinal Preparation (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyesters Or Polycarbonates (AREA)
NL950010C 1982-11-08 1995-06-15 R¦ntgencontrastmiddelen. NL950010I1 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8231796 1982-11-08

Publications (2)

Publication Number Publication Date
NL950010I2 NL950010I2 (nl) 1997-02-03
NL950010I1 true NL950010I1 (nl) 1997-02-03

Family

ID=10534110

Family Applications (1)

Application Number Title Priority Date Filing Date
NL950010C NL950010I1 (nl) 1982-11-08 1995-06-15 R¦ntgencontrastmiddelen.

Country Status (10)

Country Link
US (1) US5349085A (enExample)
EP (1) EP0108638B1 (enExample)
JP (1) JPS59104352A (enExample)
AT (1) ATE20733T1 (enExample)
DE (1) DE3364536D1 (enExample)
DK (1) DK160868C (enExample)
HK (1) HK46791A (enExample)
LU (1) LU88639I2 (enExample)
NL (1) NL950010I1 (enExample)
NO (2) NO161368C (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
GB8919929D0 (en) * 1989-09-04 1989-10-18 Nycomed As Compositions
IT1252180B (it) * 1991-12-10 1995-06-05 Bracco Ind Chimica Spa 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
WO1994022810A1 (es) * 1993-04-01 1994-10-13 Centro Investigacion Justesa Imagen, S.A. Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
US5840967A (en) * 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9720969D0 (en) * 1997-10-02 1997-12-03 Nycomed Imaging As Process
GB9903109D0 (en) * 1999-02-11 1999-04-07 Nycomed Imaging As Process
US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
EP1490090A4 (en) 2002-02-22 2006-09-20 New River Pharmaceuticals Inc SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS
KR100574087B1 (ko) 2004-09-09 2006-04-27 주식회사태준제약 아이오디사놀의 제조방법
WO2006074809A2 (en) 2005-01-13 2006-07-20 Cinvention Ag Composite materials containing carbon nanoparticles
EP1966110B1 (en) 2005-12-19 2013-04-24 Ge Healthcare As Purification process of iodixanol
US8124806B2 (en) 2006-02-15 2012-02-28 Ge Healthcare As Contrast agents
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
US7662859B2 (en) 2007-02-16 2010-02-16 Ge Healthcare As Contrast agents
WO2009008734A2 (en) * 2007-07-12 2009-01-15 Ge Healthcare As Contrast agents
WO2009047316A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
ES2389974T3 (es) 2007-10-12 2012-11-05 Ge Healthcare As Agentes de contraste
JP2011500533A (ja) 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
EP2200655B1 (en) 2007-10-12 2012-07-18 GE Healthcare AS Contrast agents
EP2245004A2 (en) * 2008-02-27 2010-11-03 GE Healthcare AS Contrast agents
US8535642B2 (en) 2008-02-27 2013-09-17 Ge Healthcare As Contrast agents
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
JP2012514622A (ja) * 2009-01-09 2012-06-28 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影製剤組成物
US7999135B2 (en) 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using ultrasound
US7696381B1 (en) * 2009-07-21 2010-04-13 Ge Healthcare As Alternative dimerisation reagents for synthesis of iodixanol
US20110021821A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous acetylation process in synthesis of non-ionic x-ray contrast agents
US7754920B1 (en) * 2009-07-21 2010-07-13 Ge Healthcare As Solvent reduction in crystallisation of intermediate for non-ionic X-ray contrast agents
US7999134B2 (en) * 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using milling
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
US8962887B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol
US8962886B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in methanol
US20110021832A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Synthesis of iodixanol in water
US8969619B2 (en) * 2009-07-21 2015-03-03 Ge Healthcare As Synthesis of iodixanol in propyleneglycol
AU2010311478B2 (en) * 2009-10-29 2015-09-24 Ge Healthcare As Diagnostic composition comprising plasma cations having superior safety profile
AU2009355814B2 (en) * 2009-11-26 2016-06-30 Imax Diagnostic Imaging Holding Ltd Preparation and purification of iodixanol
EP2593143A1 (en) 2010-07-12 2013-05-22 GE Healthcare AS X-ray imaging at low contrast agent concentrations and/or low dose radiation
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN102816125B (zh) * 2011-06-08 2014-03-26 浙江司太立制药股份有限公司 一种造影剂
JP6423274B2 (ja) 2012-01-11 2018-11-14 ジーイー・ヘルスケア・アクスイェ・セルスカプ ヨウ素濃度の低いｘ線イメージング造影製剤及びｘ線イメージング法
US9884808B2 (en) 2012-09-27 2018-02-06 Ge Healthcare As Preparation of an intermediate compound of ioforminol
US9403757B2 (en) 2012-11-12 2016-08-02 Ge Healthcare As Preparation of intermediates of X-ray contrast agents
JP6884698B2 (ja) 2014-11-21 2021-06-09 テクニカル ユニバーシティ オブ デンマークＴｅｃｈｎｉｃａｌ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｄｅｎｍａｒｋ 局所的薬物放出のためのゲル処方物
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
CA3023928A1 (en) 2016-05-20 2017-11-23 Technical University Of Denmark Palpable marker composition
CN111440084B (zh) * 2019-01-16 2023-01-06 苏州纳微科技股份有限公司 一种碘克沙醇的纯化方法
WO2020249801A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release
CN113121377A (zh) * 2019-12-31 2021-07-16 江苏汉邦科技有限公司 碘克沙醇的纯化方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE344166B (enExample) * 1966-12-13 1972-04-04 Pharmacia Ab
SE315974B (enExample) * 1967-12-28 1969-10-13 Pharmacia Ab
US3804892A (en) * 1967-12-28 1974-04-16 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
US3763227A (en) * 1967-12-28 1973-10-02 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
SE315975B (enExample) * 1967-12-28 1969-10-13 Pharmacia Ab
ES381202A1 (es) * 1969-06-27 1973-04-16 Nyegaard & Co As Un procedimiento para la preparacion de agentes de contras-te de rayos x.
NL7102816A (enExample) * 1970-03-12 1971-09-14
DD104193A5 (enExample) * 1972-12-22 1974-03-05
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3038853A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus

Also Published As

Publication number Publication date
LU88639I2 (fr) 1996-02-01
DK508283D0 (da) 1983-11-07
NL950010I2 (nl) 1997-02-03
NO1994015I1 (no) 1994-09-05
JPS6355509B2 (enExample) 1988-11-02
ATE20733T1 (de) 1986-08-15
EP0108638B1 (en) 1986-07-16
NO834056L (no) 1984-05-09
DK160868B (da) 1991-04-29
DE3364536D1 (en) 1986-08-21
JPS59104352A (ja) 1984-06-16
NO161368B (no) 1989-05-02
EP0108638A1 (en) 1984-05-16
US5349085A (en) 1994-09-20
DK160868C (da) 1991-10-14
HK46791A (en) 1991-06-21
NO161368C (no) 1989-08-09
DK508283A (da) 1984-05-09

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