ATE20733T1 - Roentgenkontrastmittel. - Google Patents

Roentgenkontrastmittel.

Info

Publication number
ATE20733T1
ATE20733T1 AT83306766T AT83306766T ATE20733T1 AT E20733 T1 ATE20733 T1 AT E20733T1 AT 83306766 T AT83306766 T AT 83306766T AT 83306766 T AT83306766 T AT 83306766T AT E20733 T1 ATE20733 T1 AT E20733T1
Authority
AT
Austria
Prior art keywords
ch2ch
group
contrast agent
ray contrast
ch2oh
Prior art date
Application number
AT83306766T
Other languages
English (en)
Inventor
Per-Egil Hansen
Hugo Holtermann
Knut Wille
Original Assignee
Nyegaard & Co As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As
Application granted granted Critical
Publication of ATE20733T1 publication Critical patent/ATE20733T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT83306766T 1982-11-08 1983-11-07 Roentgenkontrastmittel. ATE20733T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8231796 1982-11-08
EP83306766A EP0108638B1 (de) 1982-11-08 1983-11-07 Röntgenkontrastmittel

Publications (1)

Publication Number Publication Date
ATE20733T1 true ATE20733T1 (de) 1986-08-15

Family

ID=10534110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83306766T ATE20733T1 (de) 1982-11-08 1983-11-07 Roentgenkontrastmittel.

Country Status (10)

Country Link
US (1) US5349085A (de)
EP (1) EP0108638B1 (de)
JP (1) JPS59104352A (de)
AT (1) ATE20733T1 (de)
DE (1) DE3364536D1 (de)
DK (1) DK160868C (de)
HK (1) HK46791A (de)
LU (1) LU88639I2 (de)
NL (1) NL950010I2 (de)
NO (2) NO161368C (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
GB8919929D0 (en) * 1989-09-04 1989-10-18 Nycomed As Compositions
IT1252180B (it) * 1991-12-10 1995-06-05 Bracco Ind Chimica Spa 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
WO1994022810A1 (es) * 1993-04-01 1994-10-13 Centro Investigacion Justesa Imagen, S.A. Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
US5840967A (en) * 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9720969D0 (en) 1997-10-02 1997-12-03 Nycomed Imaging As Process
GB9903109D0 (en) * 1999-02-11 1999-04-07 Nycomed Imaging As Process
AU2002245169A1 (en) 2000-11-10 2002-07-08 Wm. Marsh Rice University Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
KR100574087B1 (ko) 2004-09-09 2006-04-27 주식회사태준제약 아이오디사놀의 제조방법
SI1836239T1 (sl) 2005-01-13 2009-04-30 Cinv Ag Kompozitni materiali, ki vsebujejo ogljikove nanodelce
PL1966110T3 (pl) 2005-12-19 2013-09-30 Ge Healthcare As Sposób oczyszczania jodiksanolu
EP1989179B1 (de) 2006-02-15 2011-01-26 Ge Healthcare As Kontrastmittel
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
US7662859B2 (en) 2007-02-16 2010-02-16 Ge Healthcare As Contrast agents
EP2178568B1 (de) * 2007-07-12 2014-07-02 Ge Healthcare As Kontrastmittel
EP2200971B1 (de) 2007-10-12 2013-04-24 GE Healthcare AS Kontrastmittel
JP2011500533A (ja) 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
WO2009047318A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
JP2011500530A (ja) 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US20110008263A1 (en) * 2008-02-27 2011-01-13 Hanno Priebe Contrast agents
EP2245003A2 (de) * 2008-02-27 2010-11-03 GE Healthcare AS Kontrastmittel
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
US20110256068A1 (en) * 2009-01-09 2011-10-20 Wistand Lars-Goeran Contrast media compositions
US7999135B2 (en) 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using ultrasound
US8962886B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in methanol
US8962887B2 (en) * 2009-07-21 2015-02-24 Ge Healthcare As Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol
US7999134B2 (en) * 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using milling
US7754920B1 (en) * 2009-07-21 2010-07-13 Ge Healthcare As Solvent reduction in crystallisation of intermediate for non-ionic X-ray contrast agents
US20110021832A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Synthesis of iodixanol in water
US7696381B1 (en) 2009-07-21 2010-04-13 Ge Healthcare As Alternative dimerisation reagents for synthesis of iodixanol
US20110021821A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous acetylation process in synthesis of non-ionic x-ray contrast agents
US8969619B2 (en) 2009-07-21 2015-03-03 Ge Healthcare As Synthesis of iodixanol in propyleneglycol
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
DK2493511T3 (da) * 2009-10-29 2013-11-25 Ge Healthcare As Diagnostisk sammensætning omfattende plasmakationer som har en forbedret sikkerhedsprofil
ES2607481T3 (es) 2009-11-26 2017-03-31 Imax Diagnostic Imaging Holding Limited Preparación y purificación de iodixanol
CN102985114A (zh) 2010-07-12 2013-03-20 通用电气医疗集团股份有限公司 以低造影剂浓度和/或低剂量辐射的x-射线成像
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN102816125B (zh) * 2011-06-08 2014-03-26 浙江司太立制药股份有限公司 一种造影剂
US10004816B2 (en) 2012-01-11 2018-06-26 Ge Healthcare As X-ray imaging contrast media with low iodine concentration and X-ray imaging process
CN110003038A (zh) 2012-09-27 2019-07-12 通用电气医疗集团股份有限公司 Ioforminol的中间体化合物的制备
PL2917174T3 (pl) 2012-11-12 2019-01-31 Ge Healthcare As Wytwarzanie związków pośrednich dla rentgenowskich środków kontrastowych
WO2016079330A1 (en) 2014-11-21 2016-05-26 Technical University Of Denmark Gel formulations for local drug release
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
MX2018014087A (es) 2016-05-20 2019-06-10 Univ Denmark Tech Dtu Composicion de marcaje palpable.
CN111440084B (zh) * 2019-01-16 2023-01-06 苏州纳微科技股份有限公司 一种碘克沙醇的纯化方法
CA3143104A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release
CN113121377A (zh) * 2019-12-31 2021-07-16 江苏汉邦科技有限公司 碘克沙醇的纯化方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE344166B (de) * 1966-12-13 1972-04-04 Pharmacia Ab
US3763227A (en) * 1967-12-28 1973-10-02 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
US3804892A (en) * 1967-12-28 1974-04-16 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
SE315975B (de) * 1967-12-28 1969-10-13 Pharmacia Ab
SE315974B (de) * 1967-12-28 1969-10-13 Pharmacia Ab
CH544551A (de) * 1969-06-27 1973-11-30 Nyegaard & Co As Neue Röntgenkontrastmittel
NL7102816A (de) * 1970-03-12 1971-09-14
DD104193A5 (de) * 1972-12-22 1974-03-05
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3038853A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus

Also Published As

Publication number Publication date
NO161368C (no) 1989-08-09
NL950010I1 (nl) 1997-02-03
LU88639I2 (fr) 1996-02-01
JPS6355509B2 (de) 1988-11-02
NL950010I2 (nl) 1997-02-03
JPS59104352A (ja) 1984-06-16
NO1994015I1 (no) 1994-09-05
DK508283A (da) 1984-05-09
DE3364536D1 (en) 1986-08-21
DK160868B (da) 1991-04-29
DK508283D0 (da) 1983-11-07
EP0108638A1 (de) 1984-05-16
EP0108638B1 (de) 1986-07-16
DK160868C (da) 1991-10-14
US5349085A (en) 1994-09-20
NO834056L (no) 1984-05-09
NO161368B (no) 1989-05-02
HK46791A (en) 1991-06-21

Similar Documents

Publication Publication Date Title
ATE20733T1 (de) Roentgenkontrastmittel.
ATE38672T1 (de) 7-oxabicycloheptan aminosubstituierte prostaglandinaehnliche verbindungen.
MX9203271A (es) Composicion opascificante inyectable para examenes con rayos x.
IT8222605A0 (it) Procedimento per la sintesi di monometileteri dei glicoli.
FR2355808A1 (fr) Anilides iodes utilisables comme agents de contraste
FR2372806A1 (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
JPS55113775A (en) Manufacture of 4*55perfluoroo1*33dioxolan compound
SE8307146D0 (sv) 7-oxabicykloheptan-substituerade aminoprostaglandinanaloger
NO1994014I1 (no) Iopentol/ N,N<O>1</O>-bis(2,3dihydroksypropyl)-5-[N-2-hydroksy-3-metoksypropyl)acetamido]-2,4,6-trijod-isoftalamid
ES8101897A1 (es) Lateter mejorado para un solo uso.
FI77021B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-imino-pyrrolidiner.
JPS5392071A (en) Diaphragm type coupling
ES546974A0 (es) Un procedimiento de eliminacion del virus lav.
FR2446279A1 (fr) Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs
FR2634057B1 (fr) Procede de fabrication d'un tube perfectionne intensificateur d'images radiologiques, tube intensificateur ainsi obtenu
ZA838571B (en) Heterocyclically substituted nitriles,their preparation and their use as drugs
SE8502780D0 (sv) Aziridinderivat
SE8401030D0 (sv) Use of perfluorobromoalkyl ethers as x-ray contrast agents
JPS51142088A (en) Aminocyclodextrin derivatives and their prepapation.
HUT64939A (en) Method for producing (2r,3s)-beta-phenyl-isoserine and its salts and their applications for producing taxane derivatives
JPS52117573A (en) Electronic beam exposure unit
JPS51137170A (en) Filter housing
BE888646A (fr) Preparation de composes du furanne,
JPS5228889A (en) Tomographic image pickup device
JPS548803A (en) Supporter for stator coil end