DK157193C - Analogifremgangsmaade til fremstilling af carbostyrilforbindelser - Google Patents
Analogifremgangsmaade til fremstilling af carbostyrilforbindelserInfo
- Publication number
- DK157193C DK157193C DK307482A DK307482A DK157193C DK 157193 C DK157193 C DK 157193C DK 307482 A DK307482 A DK 307482A DK 307482 A DK307482 A DK 307482A DK 157193 C DK157193 C DK 157193C
- Authority
- DK
- Denmark
- Prior art keywords
- carbostyr
- relations
- analogue
- preparation
- carbostyr relations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15901680 | 1980-11-11 | ||
| JP55159016A JPS5782390A (en) | 1980-11-11 | 1980-11-11 | Carbostyril derivative |
| JP55179950A JPS57102888A (en) | 1980-12-18 | 1980-12-18 | Carbostyril derivative |
| JP17995080 | 1980-12-18 | ||
| JP8100328 | 1981-11-11 | ||
| PCT/JP1981/000328 WO1982001706A1 (en) | 1980-11-11 | 1981-11-11 | Carbostyril compounds,composition containing same,and process for their preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK307482A DK307482A (da) | 1982-07-08 |
| DK157193B DK157193B (da) | 1989-11-20 |
| DK157193C true DK157193C (da) | 1990-04-09 |
Family
ID=26485945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK307482A DK157193C (da) | 1980-11-11 | 1982-07-08 | Analogifremgangsmaade til fremstilling af carbostyrilforbindelser |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4414390A (de) |
| EP (1) | EP0052016B1 (de) |
| KR (1) | KR880001657B1 (de) |
| AT (1) | AT382376B (de) |
| AU (1) | AU547586B2 (de) |
| CA (1) | CA1164459A (de) |
| CH (1) | CH653684A5 (de) |
| DE (1) | DE3152512T1 (de) |
| DK (1) | DK157193C (de) |
| ES (1) | ES507545A0 (de) |
| FI (1) | FI71145C (de) |
| IT (1) | IT8149680A0 (de) |
| MX (1) | MX6802E (de) |
| NO (1) | NO157819C (de) |
| PH (1) | PH17158A (de) |
| PT (1) | PT73959B (de) |
| SE (1) | SE440653B (de) |
| SU (1) | SU1215621A3 (de) |
| WO (1) | WO1982001706A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4636502A (en) * | 1982-12-27 | 1987-01-13 | Eli Lilly And Company | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines |
| US4537889A (en) * | 1982-12-27 | 1985-08-27 | Eli Lilly And Company | Inotropic agents |
| GB8305245D0 (en) * | 1983-02-25 | 1983-03-30 | Fujisawa Pharmaceutical Co | Imidazo-heterocyclic compounds |
| US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
| US4710507A (en) * | 1983-12-22 | 1987-12-01 | Pfizer Inc. | Quinolone inotropic agents |
| ES8608874A1 (es) * | 1984-05-29 | 1986-09-01 | Pfizer | Un procedimiento para la preparacion de una 2-(1h)-quinolona |
| US4721721A (en) * | 1984-12-18 | 1988-01-26 | Rorer Pharmaceutical Corporation | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses |
| FR2580646A1 (fr) * | 1985-04-19 | 1986-10-24 | Synthelabo | Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8619902D0 (en) * | 1986-08-15 | 1986-09-24 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8709448D0 (en) * | 1987-04-21 | 1987-05-28 | Pfizer Ltd | Heterobicyclic quinoline derivatives |
| ATE210663T1 (de) * | 1994-06-20 | 2001-12-15 | Takeda Chemical Industries Ltd | Kondensierte imidazolderivate, ihre herstellung und verwendung |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| DE10247271A1 (de) * | 2002-10-10 | 2004-08-26 | Grünenthal GmbH | Substituierte C-Imidazo[1,2-a]pyridin-3-yle |
| PE20050211A1 (es) * | 2003-04-02 | 2005-04-27 | Novartis Ag | Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas |
| DE102005019181A1 (de) * | 2005-04-25 | 2006-10-26 | Novartis Ag | Peptid-Deformylase (PDF) Inhibitoren 1 |
| WO2010032195A1 (en) * | 2008-09-16 | 2010-03-25 | Csir | Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors |
| ES2362894B1 (es) * | 2009-11-16 | 2012-05-21 | Ferrer Internacional S.A. | Procedimiento de preparación del �?cido 4-nitro-oxi-metil-benzoico. |
| CN107810188B (zh) * | 2015-04-08 | 2020-09-22 | 拜耳作物科学股份公司 | 作为害虫防治剂和中间体产物的稠合双环杂环衍生物 |
| US10517870B2 (en) | 2015-07-30 | 2019-12-31 | Bristol-Myers Squibb Company | Aryl substituted bicycle heteroaryl compounds |
| ES2823180T3 (es) * | 2016-07-14 | 2021-05-06 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos con heteroarilo |
| EP3484894B1 (de) * | 2016-07-14 | 2020-08-19 | Bristol-Myers Squibb Company | Tricyclische heteroarylsubstituierte chinolin- und azachinolinverbindungen als par4-hemmer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1473819A (en) * | 1976-01-28 | 1977-05-18 | Gallardo Antonio Sa | Derivatives of imidazo 1,2-a pyridine |
| ES8100016A1 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 1-(4-aminopiperidino)-3,4-dihidroisoquinoleina. |
| ES8100015A1 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina. |
| JPS5553284A (en) * | 1978-10-12 | 1980-04-18 | Yoshitomi Pharmaceut Ind Ltd | Pyridazinone derivative |
| GB2031404A (en) * | 1978-10-17 | 1980-04-23 | Yoshitomi Pharmaceutical | Pyridazinone compounds |
-
1981
- 1981-10-29 CA CA000389034A patent/CA1164459A/en not_active Expired
- 1981-11-10 PH PH26478A patent/PH17158A/en unknown
- 1981-11-10 PT PT73959A patent/PT73959B/pt not_active IP Right Cessation
- 1981-11-11 US US06/403,582 patent/US4414390A/en not_active Expired - Lifetime
- 1981-11-11 AU AU78085/81A patent/AU547586B2/en not_active Ceased
- 1981-11-11 AT AT0908381A patent/AT382376B/de not_active IP Right Cessation
- 1981-11-11 IT IT8149680A patent/IT8149680A0/it unknown
- 1981-11-11 DE DE813152512T patent/DE3152512T1/de active Granted
- 1981-11-11 CH CH4324/82A patent/CH653684A5/fr not_active IP Right Cessation
- 1981-11-11 ES ES507545A patent/ES507545A0/es active Granted
- 1981-11-11 EP EP81305344A patent/EP0052016B1/de not_active Expired
- 1981-11-11 WO PCT/JP1981/000328 patent/WO1982001706A1/ja active IP Right Grant
- 1981-11-11 MX MX819760U patent/MX6802E/es unknown
- 1981-11-11 KR KR1019810004359A patent/KR880001657B1/ko active
-
1982
- 1982-07-08 DK DK307482A patent/DK157193C/da not_active IP Right Cessation
- 1982-07-08 SE SE8204237A patent/SE440653B/sv not_active IP Right Cessation
- 1982-07-09 NO NO82822391A patent/NO157819C/no unknown
- 1982-07-11 SU SU823466402A patent/SU1215621A3/ru active
- 1982-07-12 FI FI822471A patent/FI71145C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE8204237L (sv) | 1982-07-08 |
| FI822471A0 (fi) | 1982-07-12 |
| NO157819B (no) | 1988-02-15 |
| SE440653B (sv) | 1985-08-12 |
| IT8149680A0 (it) | 1981-11-11 |
| MX6802E (es) | 1986-07-29 |
| KR880001657B1 (ko) | 1988-09-05 |
| WO1982001706A1 (en) | 1982-05-27 |
| FI71145B (fi) | 1986-08-14 |
| ES8301967A1 (es) | 1983-02-01 |
| CH653684A5 (fr) | 1986-01-15 |
| AT382376B (de) | 1987-02-25 |
| NO157819C (no) | 1988-05-25 |
| SE8204237D0 (sv) | 1982-07-08 |
| KR830007644A (ko) | 1983-11-04 |
| DK157193B (da) | 1989-11-20 |
| SU1215621A3 (ru) | 1986-02-28 |
| EP0052016A1 (de) | 1982-05-19 |
| PH17158A (en) | 1984-06-13 |
| CA1164459A (en) | 1984-03-27 |
| NO822391L (no) | 1982-07-09 |
| ES507545A0 (es) | 1983-02-01 |
| ATA908381A (de) | 1986-07-15 |
| AU7808581A (en) | 1982-06-07 |
| DE3152512C2 (de) | 1991-01-03 |
| DK307482A (da) | 1982-07-08 |
| FI822471L (fi) | 1982-07-12 |
| PT73959B (en) | 1983-04-18 |
| US4414390A (en) | 1983-11-08 |
| EP0052016B1 (de) | 1984-09-05 |
| DE3152512T1 (de) | 1982-11-18 |
| FI71145C (fi) | 1986-11-24 |
| PT73959A (en) | 1981-12-01 |
| AU547586B2 (en) | 1985-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |