DK157022C - Analogifremgangsmaade til fremstilling af 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido oe1,2-aaapyrimidinderivater eller farmaceutisk acceptable salte, hydrater, stereoisomere, optisk aktive isomere, geometriske isomere og tautomere deraf - Google Patents

Analogifremgangsmaade til fremstilling af 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido oe1,2-aaapyrimidinderivater eller farmaceutisk acceptable salte, hydrater, stereoisomere, optisk aktive isomere, geometriske isomere og tautomere deraf

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Publication number
DK157022C
DK157022C DK585578A DK585578A DK157022C DK 157022 C DK157022 C DK 157022C DK 585578 A DK585578 A DK 585578A DK 585578 A DK585578 A DK 585578A DK 157022 C DK157022 C DK 157022C
Authority
DK
Denmark
Prior art keywords
aaapyrimidine
optimism
hydrazono
pyrido
stereoisomers
Prior art date
Application number
DK585578A
Other languages
Danish (da)
English (en)
Other versions
DK157022B (da
DK585578A (da
Inventor
Istvan Hermecz
Zoltan Meszaros
Tibor Breining
Sandor Virag
Lelle Vasvari
Agnes Horvath
Gabor Nagy
Attila Mandi
Tamas Szuecs
Istvan Bitter
Gyula Sebestyen
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of DK585578A publication Critical patent/DK585578A/da
Publication of DK157022B publication Critical patent/DK157022B/da
Application granted granted Critical
Publication of DK157022C publication Critical patent/DK157022C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK585578A 1977-12-29 1978-12-28 Analogifremgangsmaade til fremstilling af 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido oe1,2-aaapyrimidinderivater eller farmaceutisk acceptable salte, hydrater, stereoisomere, optisk aktive isomere, geometriske isomere og tautomere deraf DK157022C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU77CI1794A HU178496B (en) 1977-12-29 1977-12-29 Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
HUCI001794 1977-12-29

Publications (3)

Publication Number Publication Date
DK585578A DK585578A (da) 1979-06-30
DK157022B DK157022B (da) 1989-10-30
DK157022C true DK157022C (da) 1990-04-02

Family

ID=10994683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK585578A DK157022C (da) 1977-12-29 1978-12-28 Analogifremgangsmaade til fremstilling af 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido oe1,2-aaapyrimidinderivater eller farmaceutisk acceptable salte, hydrater, stereoisomere, optisk aktive isomere, geometriske isomere og tautomere deraf

Country Status (29)

Country Link
US (2) US4234586A (de)
JP (1) JPS5495598A (de)
AR (3) AR222985A1 (de)
AT (1) AT375936B (de)
AU (1) AU520428B2 (de)
BE (1) BE873194A (de)
CA (1) CA1130284A (de)
CH (1) CH642078A5 (de)
CS (1) CS244654B2 (de)
DD (1) DD139854A5 (de)
DE (1) DE2854115A1 (de)
DK (1) DK157022C (de)
ES (7) ES476442A1 (de)
FI (1) FI66614C (de)
FR (1) FR2413389A1 (de)
GB (1) GB2011898B (de)
GR (1) GR68357B (de)
HU (1) HU178496B (de)
IL (1) IL56078A (de)
IT (1) IT1203210B (de)
LU (1) LU80601A1 (de)
NL (1) NL7812547A (de)
NO (1) NO151287C (de)
PL (5) PL119641B1 (de)
PT (1) PT68935A (de)
SE (1) SE438675B (de)
SU (2) SU999972A3 (de)
YU (3) YU42093B (de)
ZA (1) ZA787385B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
US4482557A (en) * 1979-05-11 1984-11-13 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity
HU176942B (hu) * 1979-05-11 1981-06-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija 2,3- i 3,4-dvuzamehhjonnykh tetragidro-pirrolo!1,2-a!-pirimidinov
HU178452B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 9-substituted amino-4-oxo-6,7-dihydro-4h-pyrido/1,2-a/pyrimidine derivatives
HU179443B (en) * 1979-05-11 1982-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
AT381093B (de) * 1980-06-24 1986-08-25 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung neuer 6-hydrazono-pyrido(2,1-b)chinazolin-11-on-deriv te, von deren salzen sowie von deren stereomeren
HU183173B (en) * 1980-06-24 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 6-hydrazono-pyrido-aracket-2,1-b-bracket closed-quinazolin-11-ones
HU183408B (en) 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
US4395549A (en) * 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
US5344933A (en) * 1991-09-11 1994-09-06 Fuji Photo Film Co., Ltd. Pyrrole ring-or condensed pyrrole ring-containing azomethine dye
EP1790649A1 (de) * 2005-11-21 2007-05-30 Sanofi-Aventis Substituierte bicyclische Pyrimidone Derivaten
EP2138498A1 (de) 2008-06-26 2009-12-30 sanofi-aventis Substituierte trizyklische Derivate gegen neurodegenerative Erkrankungen
EP2138495A1 (de) 2008-06-26 2009-12-30 sanofi-aventis Substituierte Pyrimido[2,1-a]isochinolin-4-on-Derivate
EP2138488A1 (de) 2008-06-26 2009-12-30 sanofi-aventis 4-(Pyridin-4-yl)-1H-[1,3,5]Triazin-2-one-Verbindungen als GSK3-beta Hemmer zur Behandlung neurodegenerative Erkrankungen
EP2138492A1 (de) * 2008-06-26 2009-12-30 Sanofi-Aventis Substituierte Pyrimidin-4-one-Derivate
EP2138493A1 (de) 2008-06-26 2009-12-30 Sanofi-Aventis Substituierte Pyrimidon-Derivate
EP2138494A1 (de) * 2008-06-26 2009-12-30 Sanofi-Aventis Substituierte Alkylpyrimidin-4-one-Derivate
EP2138485A1 (de) 2008-06-26 2009-12-30 sanofi-aventis Substituierte N-Oxid-Pyrazin-Derivate

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786056A (en) * 1954-05-03 1957-03-19 Merck & Co Inc Acylamido-hydroxy pteridines and preparation thereof
US2894031A (en) * 1958-09-16 1959-07-07 Grace W R & Co Process for cyclohexanone hydrazone hydrate
US3140315A (en) * 1959-02-18 1964-07-07 Bayer Ag Alkyl-substituted hydrazines and hydrazones and process for preparation thereof
FR1255365A (fr) * 1959-12-22 1961-03-10 Cfmc Nouveaux colorants basiques, leur procédé de préparation et leurs applications
US3141043A (en) * 1961-03-24 1964-07-14 Purdue Research Foundation Cyclopentadienylimines, process for their production and condensation products thereof
CH441366A (de) * 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
US3417082A (en) * 1965-08-16 1968-12-17 Polaroid Corp Novel chemical compounds and syntheses
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU168014B (de) * 1973-03-30 1976-02-28
US4024132A (en) * 1973-09-07 1977-05-17 Ciba-Geigy Corporation Azomethine pigments
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
YU41538B (en) 1987-08-31
GB2011898A (en) 1979-07-18
AR228949A1 (es) 1983-05-13
US4461769A (en) 1984-07-24
GR68357B (de) 1981-12-23
CH642078A5 (de) 1984-03-30
IT7869933A0 (it) 1978-12-22
FI66614C (fi) 1984-11-12
ES481747A1 (es) 1980-07-01
YU279582A (en) 1983-10-31
FR2413389B1 (de) 1982-03-26
YU42062B (en) 1988-04-30
YU42093B (en) 1988-04-30
ZA787385B (en) 1980-02-27
NL7812547A (nl) 1979-07-03
DE2854115A1 (de) 1979-07-12
ES481748A1 (es) 1980-07-01
FI66614B (fi) 1984-07-31
NO151287B (no) 1984-12-03
AT375936B (de) 1984-09-25
DD139854A5 (de) 1980-01-23
SU999972A3 (ru) 1983-02-23
FR2413389A1 (fr) 1979-07-27
BE873194A (fr) 1979-04-17
NO151287C (no) 1985-03-13
DK157022B (da) 1989-10-30
SU978730A3 (ru) 1982-11-30
PL122965B1 (en) 1982-09-30
PL119641B1 (en) 1982-01-30
AR227882A1 (es) 1982-12-30
DE2854115C2 (de) 1988-07-28
PL119520B1 (en) 1982-01-30
JPS5495598A (en) 1979-07-28
ATA873678A (de) 1984-02-15
PL212212A1 (de) 1980-02-25
CA1130284A (en) 1982-08-24
PL119501B1 (en) 1982-01-30
AU520428B2 (en) 1982-01-28
ES481745A1 (es) 1980-07-01
PL125321B1 (en) 1983-04-30
AU4262778A (en) 1979-07-05
ES481746A1 (es) 1980-07-01
PT68935A (en) 1979-01-01
ES476442A1 (es) 1979-11-16
IL56078A (en) 1982-11-30
US4234586A (en) 1980-11-18
CS244654B2 (en) 1986-08-14
ES481744A1 (es) 1980-06-16
AR222985A1 (es) 1981-07-15
IL56078A0 (en) 1979-01-31
DK585578A (da) 1979-06-30
GB2011898B (en) 1982-04-28
NO784393L (no) 1979-07-02
FI784013A (fi) 1979-06-30
YU296478A (en) 1983-10-31
HU178496B (en) 1982-05-28
SE7813226L (sv) 1979-06-30
CS909178A2 (en) 1985-08-15
LU80601A1 (de) 1979-03-22
SE438675B (sv) 1985-04-29
IT1203210B (it) 1989-02-15
ES481749A1 (es) 1980-07-01
JPH0146514B2 (de) 1989-10-09
YU279682A (en) 1983-10-31

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