DK1485348T3 - Carbonylamino-derivater som nye inhibitorer af histandeacetylase - Google Patents

Carbonylamino-derivater som nye inhibitorer af histandeacetylase

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Publication number
DK1485348T3
DK1485348T3 DK03708215T DK03708215T DK1485348T3 DK 1485348 T3 DK1485348 T3 DK 1485348T3 DK 03708215 T DK03708215 T DK 03708215T DK 03708215 T DK03708215 T DK 03708215T DK 1485348 T3 DK1485348 T3 DK 1485348T3
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DK
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Prior art keywords
histane
deacetylase
novel inhibitors
carbonylamino derivatives
carbonylamino
Prior art date
Application number
DK03708215T
Other languages
Danish (da)
English (en)
Inventor
Emelen Kristof Van
Marc Gustaaf Celine Verdonck
Brandt Sven Franciscus Anna Van
Leo Jacobus Jozef Backx
Original Assignee
Janssen Pharmaceutica Nv
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Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
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Publication of DK1485348T3 publication Critical patent/DK1485348T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/402—1-aryl substituted, e.g. piretanide
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DK03708215T 2002-03-13 2003-03-11 Carbonylamino-derivater som nye inhibitorer af histandeacetylase DK1485348T3 (da)

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US6897220B2 (en) 2001-09-14 2005-05-24 Methylgene, Inc. Inhibitors of histone deacetylase
BR0307606A (pt) 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Derivados de piperazinila, piperidinila e morfolinila como inibidores de histona desacetilase
EA007272B1 (ru) * 2002-03-13 2006-08-25 Янссен Фармацевтика Н. В. Новые ингибиторы гистондеацетилазы
MXPA04007776A (es) 2002-03-13 2004-10-15 Janssen Pharmaceutica Nv Derivados de sulfonilamino como nuevos inhibidores de histona deacetilasa.
ATE398105T1 (de) * 2002-03-13 2008-07-15 Janssen Pharmaceutica Nv Carbonylamino- derivativate als neue inhibitoren von histone deacetylase
TWI319387B (en) 2002-04-05 2010-01-11 Astrazeneca Ab Benzamide derivatives
US8163764B2 (en) * 2002-04-26 2012-04-24 Asan Laboratories Company (Cayman) Limited Skincare methods
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CA2476067C (fr) 2011-09-20
US8394831B2 (en) 2013-03-12
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ATE398105T1 (de) 2008-07-15
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NZ534831A (en) 2007-01-26
HRP20040805A2 (en) 2005-04-30
DE60321548D1 (de) 2008-07-24
EA007908B1 (ru) 2007-02-27
WO2003076395A1 (fr) 2003-09-18
EP1485348B1 (fr) 2008-06-11
CN100503599C (zh) 2009-06-24
US20120041001A1 (en) 2012-02-16

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