DK1485348T3 - Carbonylamino-derivater som nye inhibitorer af histandeacetylase - Google Patents
Carbonylamino-derivater som nye inhibitorer af histandeacetylaseInfo
- Publication number
- DK1485348T3 DK1485348T3 DK03708215T DK03708215T DK1485348T3 DK 1485348 T3 DK1485348 T3 DK 1485348T3 DK 03708215 T DK03708215 T DK 03708215T DK 03708215 T DK03708215 T DK 03708215T DK 1485348 T3 DK1485348 T3 DK 1485348T3
- Authority
- DK
- Denmark
- Prior art keywords
- histane
- deacetylase
- novel inhibitors
- carbonylamino derivatives
- carbonylamino
- Prior art date
Links
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/402—1-aryl substituted, e.g. piretanide
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US7868204B2 (en) | 2001-09-14 | 2011-01-11 | Methylgene Inc. | Inhibitors of histone deacetylase |
BR0212510A (pt) | 2001-09-14 | 2004-08-24 | Methylgene Inc | Inibidor de histona desacetilase, composto e composição |
US6897220B2 (en) | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
ATE396971T1 (de) | 2002-03-13 | 2008-06-15 | Janssen Pharmaceutica Nv | Sulfonylaminoderivate als neue inhibitoren von histondeacetylase |
ES2306858T3 (es) | 2002-03-13 | 2008-11-16 | Janssen Pharmaceutica Nv | Derivados de carbonilamino como nuevos inhibidores de las histonadesacetilasas. |
PL213783B1 (pl) | 2002-03-13 | 2013-05-31 | Janssen Pharmaceutica Nv | Podstawiona pochodna piperydyny lub piperazyny, jej zastosowanie i sposób wytwarzania oraz kompozycja farmaceutyczna |
EA007270B1 (ru) | 2002-03-13 | 2006-08-25 | Янссен Фармацевтика Н.В. | Пиперазинил-, пиперидинил- и морфолинилпроизводные как новые ингибиторы гистондеацетилазы |
TWI319387B (en) | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
US8163764B2 (en) * | 2002-04-26 | 2012-04-24 | Asan Laboratories Company (Cayman) Limited | Skincare methods |
BR0317409A (pt) * | 2002-12-17 | 2005-11-08 | Pfizer | Compostos cicloalquileno amida 2-piridila e 2-pirimidila, composição farmacêutica compreendendo os mesmos e uso dos referidos compostos |
WO2005030705A1 (en) | 2003-09-24 | 2005-04-07 | Methylgene, Inc. | Inhibitors of histone deacetylase |
US7253204B2 (en) | 2004-03-26 | 2007-08-07 | Methylgene Inc. | Inhibitors of histone deacetylase |
US7638553B2 (en) | 2004-06-14 | 2009-12-29 | Hoffmann-La Roche Inc. | Hydroxamates, their manufacture and use as pharmaceutical agents |
WO2005121120A1 (en) | 2004-06-14 | 2005-12-22 | F. Hoffmann-La Roche Ag | Thiophene hydroxamic acid derivatives and their use as hdac inhibitors |
CN1980920A (zh) | 2004-06-14 | 2007-06-13 | 霍夫曼-拉罗奇有限公司 | 噻吩衍生物、它们的制备以及作为药剂的应用 |
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- 2003-03-11 MX MXPA04008796A patent/MXPA04008796A/es active IP Right Grant
- 2003-03-11 AU AU2003212336A patent/AU2003212336B2/en not_active Ceased
- 2003-03-11 DE DE60321548T patent/DE60321548D1/de not_active Expired - Lifetime
- 2003-03-11 EA EA200401200A patent/EA007908B1/ru not_active IP Right Cessation
- 2003-03-11 EP EP03708215A patent/EP1485348B1/en not_active Expired - Lifetime
- 2003-03-11 OA OA1200400243A patent/OA12789A/en unknown
- 2003-03-11 CN CNB038058847A patent/CN100503599C/zh not_active Expired - Lifetime
- 2003-03-11 NZ NZ534831A patent/NZ534831A/en unknown
- 2003-03-11 US US10/507,788 patent/US7446109B2/en active Active
- 2003-03-11 BR BR0307607-5A patent/BR0307607A/pt not_active IP Right Cessation
- 2003-03-11 CA CA2476067A patent/CA2476067C/en not_active Expired - Lifetime
- 2003-03-11 KR KR10-2004-7011327A patent/KR20040090981A/ko not_active Application Discontinuation
- 2003-03-11 WO PCT/EP2003/002512 patent/WO2003076395A1/en active IP Right Grant
- 2003-03-11 PL PL370982A patent/PL205531B1/pl unknown
- 2003-03-11 JP JP2003574617A patent/JP4648628B2/ja not_active Expired - Lifetime
- 2003-03-11 DK DK03708215T patent/DK1485348T3/da active
- 2003-03-12 AR ARP030100852A patent/AR039564A1/es not_active Application Discontinuation
- 2003-03-12 TW TW092105281A patent/TW200404794A/zh unknown
-
2004
- 2004-09-03 HR HR20040805A patent/HRP20040805A2/hr not_active Application Discontinuation
- 2004-09-30 NO NO20044146A patent/NO20044146L/no not_active Application Discontinuation
-
2008
- 2008-09-19 US US12/233,977 patent/US8071615B2/en not_active Expired - Fee Related
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2011
- 2011-10-24 US US13/280,207 patent/US8394831B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2476067C (en) | 2011-09-20 |
US8071615B2 (en) | 2011-12-06 |
EA200401200A1 (ru) | 2005-02-24 |
AR039564A1 (es) | 2005-02-23 |
EP1485348B1 (en) | 2008-06-11 |
CA2476067A1 (en) | 2003-09-18 |
US20120041001A1 (en) | 2012-02-16 |
HRP20040805A2 (en) | 2005-04-30 |
AU2003212336B2 (en) | 2008-12-18 |
MXPA04008796A (es) | 2004-11-26 |
WO2003076395A1 (en) | 2003-09-18 |
CN1642907A (zh) | 2005-07-20 |
BR0307607A (pt) | 2004-12-21 |
PL205531B1 (pl) | 2010-04-30 |
US7446109B2 (en) | 2008-11-04 |
JP2005519950A (ja) | 2005-07-07 |
EP1485348A1 (en) | 2004-12-15 |
CN100503599C (zh) | 2009-06-24 |
ATE398105T1 (de) | 2008-07-15 |
US8394831B2 (en) | 2013-03-12 |
AU2003212336A1 (en) | 2003-09-22 |
NZ534831A (en) | 2007-01-26 |
DE60321548D1 (de) | 2008-07-24 |
US20050148613A1 (en) | 2005-07-07 |
OA12789A (en) | 2006-07-10 |
PL370982A1 (en) | 2005-06-13 |
ES2306858T3 (es) | 2008-11-16 |
TW200404794A (en) | 2004-04-01 |
NO20044146L (no) | 2004-09-30 |
US20090042920A1 (en) | 2009-02-12 |
KR20040090981A (ko) | 2004-10-27 |
JP4648628B2 (ja) | 2011-03-09 |
EA007908B1 (ru) | 2007-02-27 |
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