NO20044146L - Karbonylaminoderivater som nye inhibitorer av histon-deacetylase - Google Patents
Karbonylaminoderivater som nye inhibitorer av histon-deacetylaseInfo
- Publication number
- NO20044146L NO20044146L NO20044146A NO20044146A NO20044146L NO 20044146 L NO20044146 L NO 20044146L NO 20044146 A NO20044146 A NO 20044146A NO 20044146 A NO20044146 A NO 20044146A NO 20044146 L NO20044146 L NO 20044146L
- Authority
- NO
- Norway
- Prior art keywords
- histone deacetylase
- novel inhibitors
- carbonylamino derivatives
- carbonylamino
- derivatives
- Prior art date
Links
- 102000003964 Histone deacetylase Human genes 0.000 title 1
- 108090000353 Histone deacetylase Proteins 0.000 title 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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US6897220B2 (en) | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
US7868204B2 (en) | 2001-09-14 | 2011-01-11 | Methylgene Inc. | Inhibitors of histone deacetylase |
EP1429765A2 (en) | 2001-09-14 | 2004-06-23 | Methylgene, Inc. | Inhibitors of histone deacetylase |
ES2307909T3 (es) | 2002-03-13 | 2008-12-01 | Janssen Pharmaceutica Nv | Derivados de piperazinil, piperidinil y morfolinil como nuevos inhidbidores de la histona deacetilasa. |
IL164007A0 (en) | 2002-03-13 | 2005-12-18 | Janssen Pharmaceutica Nv | New inhibitors of histone deacetylase |
ATE398105T1 (de) | 2002-03-13 | 2008-07-15 | Janssen Pharmaceutica Nv | Carbonylamino- derivativate als neue inhibitoren von histone deacetylase |
BR0307599A (pt) | 2002-03-13 | 2005-02-01 | Janssen Pharmaceutica Nv | Derivados de sulfonilamino como inibidores de histona deacetilase |
TWI319387B (en) | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
US8163764B2 (en) * | 2002-04-26 | 2012-04-24 | Asan Laboratories Company (Cayman) Limited | Skincare methods |
EP1575586A1 (en) * | 2002-12-17 | 2005-09-21 | Pfizer Japan Inc. | 2-pyridyl and 2-pyrimidyl cycloalkylene amide compounds as nr2b receptor antagonists |
EP1663953A1 (en) | 2003-09-24 | 2006-06-07 | Methylgene, Inc. | Inhibitors of histone deacetylase |
US7253204B2 (en) | 2004-03-26 | 2007-08-07 | Methylgene Inc. | Inhibitors of histone deacetylase |
WO2005121134A1 (en) | 2004-06-14 | 2005-12-22 | F. Hoffmann-La Roche Ag | Thiophene derivatives, their manufacture and use as pharmaceutical agents |
CA2566512A1 (en) | 2004-06-14 | 2005-12-22 | F. Hoffmann-La Roche Ag | Hydroxamates, their manufacture and use as pharmaceutical agents |
CN1964962A (zh) | 2004-06-14 | 2007-05-16 | 霍夫曼-拉罗奇有限公司 | 噻吩异羟肟酸衍生物以及它们作为hdac抑制剂的应用 |
MX2007001120A (es) | 2004-07-28 | 2007-03-15 | Janssen Pharmaceutica Nv | Derivados de indolil alquil sustituidos como nuevos inhibidores de la histona desacetilasa. |
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- 2003-03-11 BR BR0307607-5A patent/BR0307607A/pt not_active IP Right Cessation
- 2003-03-11 KR KR10-2004-7011327A patent/KR20040090981A/ko not_active Application Discontinuation
- 2003-03-11 EP EP03708215A patent/EP1485348B1/en not_active Expired - Lifetime
- 2003-03-11 AU AU2003212336A patent/AU2003212336B2/en not_active Ceased
- 2003-03-11 MX MXPA04008796A patent/MXPA04008796A/es active IP Right Grant
- 2003-03-12 AR ARP030100852A patent/AR039564A1/es not_active Application Discontinuation
- 2003-03-12 TW TW092105281A patent/TW200404794A/zh unknown
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2004
- 2004-09-03 HR HR20040805A patent/HRP20040805A2/hr not_active Application Discontinuation
- 2004-09-30 NO NO20044146A patent/NO20044146L/no not_active Application Discontinuation
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2008
- 2008-09-19 US US12/233,977 patent/US8071615B2/en not_active Expired - Fee Related
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2011
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Also Published As
Publication number | Publication date |
---|---|
US20050148613A1 (en) | 2005-07-07 |
DK1485348T3 (da) | 2008-09-29 |
JP2005519950A (ja) | 2005-07-07 |
TW200404794A (en) | 2004-04-01 |
NZ534831A (en) | 2007-01-26 |
PL370982A1 (en) | 2005-06-13 |
US20120041001A1 (en) | 2012-02-16 |
US8071615B2 (en) | 2011-12-06 |
OA12789A (en) | 2006-07-10 |
EA007908B1 (ru) | 2007-02-27 |
JP4648628B2 (ja) | 2011-03-09 |
AU2003212336B2 (en) | 2008-12-18 |
MXPA04008796A (es) | 2004-11-26 |
US20090042920A1 (en) | 2009-02-12 |
WO2003076395A1 (en) | 2003-09-18 |
ES2306858T3 (es) | 2008-11-16 |
US8394831B2 (en) | 2013-03-12 |
EA200401200A1 (ru) | 2005-02-24 |
US7446109B2 (en) | 2008-11-04 |
EP1485348A1 (en) | 2004-12-15 |
AR039564A1 (es) | 2005-02-23 |
DE60321548D1 (de) | 2008-07-24 |
PL205531B1 (pl) | 2010-04-30 |
AU2003212336A1 (en) | 2003-09-22 |
CA2476067A1 (en) | 2003-09-18 |
EP1485348B1 (en) | 2008-06-11 |
CN1642907A (zh) | 2005-07-20 |
HRP20040805A2 (en) | 2005-04-30 |
CN100503599C (zh) | 2009-06-24 |
KR20040090981A (ko) | 2004-10-27 |
ATE398105T1 (de) | 2008-07-15 |
CA2476067C (en) | 2011-09-20 |
BR0307607A (pt) | 2004-12-21 |
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