PL378181A1 - Pochodne kwasu hydroksamidowego jako inhibitory deacetylazy histonowej (HDAC) - Google Patents
Pochodne kwasu hydroksamidowego jako inhibitory deacetylazy histonowej (HDAC)Info
- Publication number
- PL378181A1 PL378181A1 PL378181A PL37818104A PL378181A1 PL 378181 A1 PL378181 A1 PL 378181A1 PL 378181 A PL378181 A PL 378181A PL 37818104 A PL37818104 A PL 37818104A PL 378181 A1 PL378181 A1 PL 378181A1
- Authority
- PL
- Poland
- Prior art keywords
- hdac
- inhibitors
- acid derivatives
- histone deacetylase
- hydroxamid
- Prior art date
Links
- 102000003964 Histone deacetylase Human genes 0.000 title 1
- 108090000353 Histone deacetylase Proteins 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
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| AU2003900116A AU2003900116A0 (en) | 2003-01-13 | 2003-01-13 | Hdac inhibitor |
| AU2003905406A AU2003905406A0 (en) | 2003-10-06 | HDAC Inhibitor |
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| PL378181A1 true PL378181A1 (pl) | 2006-03-06 |
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| PL378181A PL378181A1 (pl) | 2003-01-13 | 2004-01-13 | Pochodne kwasu hydroksamidowego jako inhibitory deacetylazy histonowej (HDAC) |
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| US (1) | US7135493B2 (pl) |
| EP (1) | EP1585735A1 (pl) |
| JP (1) | JP2006518341A (pl) |
| KR (1) | KR20050093826A (pl) |
| AR (1) | AR042851A1 (pl) |
| CA (1) | CA2513436A1 (pl) |
| MX (1) | MXPA05007561A (pl) |
| PL (1) | PL378181A1 (pl) |
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| KR20020070285A (ko) | 1999-11-23 | 2002-09-05 | 메틸진, 인크. | 히스톤 디아세틸라제의 억제제 |
| US20040029928A1 (en) | 2000-08-31 | 2004-02-12 | Terukage Hirata | Novel propenohydroxamic acid derivatives |
| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
| CA2423744C (en) * | 2000-09-29 | 2012-04-03 | Prolifix Limited | Hydroxamic acid compounds comprising a sulfonamide linkage as hdac inhibitors |
| WO2002030872A1 (en) | 2000-10-12 | 2002-04-18 | Maruha Corporation | Novel aliphatic compounds, process for their preparation and their usage |
| JPWO2002074298A1 (ja) | 2001-03-21 | 2004-07-08 | 小野薬品工業株式会社 | Il−6産生阻害剤 |
| CA2479906C (en) | 2002-04-03 | 2011-02-08 | Topotarget Uk Limited | Carbamic acid compounds comprising a piperazine linkage as hdac inhibitors |
| WO2003087066A1 (en) | 2002-04-11 | 2003-10-23 | Sk Chemicals, Co., Ltd. | α,β-UNSATURATED HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS |
-
2004
- 2004-01-12 TW TW093100678A patent/TW200418806A/zh unknown
- 2004-01-12 US US10/754,541 patent/US7135493B2/en not_active Expired - Fee Related
- 2004-01-13 KR KR1020057012908A patent/KR20050093826A/ko not_active Withdrawn
- 2004-01-13 JP JP2006500390A patent/JP2006518341A/ja not_active Abandoned
- 2004-01-13 WO PCT/JP2004/000157 patent/WO2004063169A1/en not_active Ceased
- 2004-01-13 AR ARP040100085A patent/AR042851A1/es unknown
- 2004-01-13 PL PL378181A patent/PL378181A1/pl not_active Application Discontinuation
- 2004-01-13 EP EP04701698A patent/EP1585735A1/en not_active Withdrawn
- 2004-01-13 MX MXPA05007561A patent/MXPA05007561A/es unknown
- 2004-01-13 CA CA002513436A patent/CA2513436A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050093826A (ko) | 2005-09-23 |
| CA2513436A1 (en) | 2004-07-29 |
| WO2004063169A1 (en) | 2004-07-29 |
| US20040229889A1 (en) | 2004-11-18 |
| TW200418806A (en) | 2004-10-01 |
| JP2006518341A (ja) | 2006-08-10 |
| AR042851A1 (es) | 2005-07-06 |
| US7135493B2 (en) | 2006-11-14 |
| EP1585735A1 (en) | 2005-10-19 |
| MXPA05007561A (es) | 2006-02-08 |
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| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |