DK146017C - Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-forbindelser - Google Patents
Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-forbindelserInfo
- Publication number
- DK146017C DK146017C DK256977A DK256977A DK146017C DK 146017 C DK146017 C DK 146017C DK 256977 A DK256977 A DK 256977A DK 256977 A DK256977 A DK 256977A DK 146017 C DK146017 C DK 146017C
- Authority
- DK
- Denmark
- Prior art keywords
- 9alfa
- 6alfa
- 17alfa
- 16beta
- 11beta
- Prior art date
Links
- 229920004518 DION® Polymers 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU75903A LU75903A1 (en, 2012) | 1976-09-29 | 1976-09-29 | |
| LU75903 | 1976-09-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK256977A DK256977A (da) | 1978-03-30 |
| DK146017B DK146017B (da) | 1983-05-24 |
| DK146017C true DK146017C (da) | 1983-10-24 |
Family
ID=19728370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK256977A DK146017C (da) | 1976-09-29 | 1977-06-09 | Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-forbindelser |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS5356652A (en, 2012) |
| AT (3) | AT363197B (en, 2012) |
| AU (1) | AU514200B2 (en, 2012) |
| BE (1) | BE859120A (en, 2012) |
| CA (1) | CA1101410A (en, 2012) |
| CH (9) | CH624967A5 (en, 2012) |
| CY (1) | CY1178A (en, 2012) |
| DD (1) | DD133150A5 (en, 2012) |
| DE (1) | DE2743069C2 (en, 2012) |
| DK (1) | DK146017C (en, 2012) |
| ES (1) | ES462763A1 (en, 2012) |
| FR (1) | FR2366311A1 (en, 2012) |
| GB (1) | GB1563638A (en, 2012) |
| HK (1) | HK16683A (en, 2012) |
| HU (1) | HU175218B (en, 2012) |
| IE (1) | IE46047B1 (en, 2012) |
| IL (1) | IL53012A (en, 2012) |
| KE (1) | KE3258A (en, 2012) |
| LU (1) | LU75903A1 (en, 2012) |
| MY (1) | MY8400092A (en, 2012) |
| NL (1) | NL7710089A (en, 2012) |
| SE (1) | SE436751B (en, 2012) |
| SG (1) | SG3383G (en, 2012) |
| ZA (1) | ZA775800B (en, 2012) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL187577C (nl) * | 1978-04-05 | 1991-11-18 | Sibla Srl | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
| DE3227312A1 (de) * | 1982-07-19 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung |
| JPH05501115A (ja) * | 1990-03-27 | 1993-03-04 | シェリング・コーポレーション | ９α―ヒドロキシ ステロイドの脱水法 |
| US5972922A (en) * | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
| EP1465855A2 (en) | 2001-11-29 | 2004-10-13 | Taro Pharmaceuticals U.S.A., Inc. | Method for the production of 6-alpha-fluoro corticosteroids |
| US11957753B2 (en) | 2010-11-22 | 2024-04-16 | Bausch Health Ireland Limited | Pharmaceutical formulations containing corticosteroids for topical administration |
| US8809307B2 (en) | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| RS60672B1 (sr) | 2015-06-18 | 2020-09-30 | Bausch Health Ireland Ltd | Topikalne kompozicije koje sadrže kortikosteroide i retinoid za lečenje psorijaze |
| US11311482B2 (en) | 2017-05-12 | 2022-04-26 | Bausch Health Us, Llc | Topical compositions and methods for treating skin diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB898292A (en) * | 1959-03-18 | 1962-06-06 | Upjohn Co | Improvements in or relating to steroids and the manufacture thereof |
| US3644340A (en) * | 1970-03-19 | 1972-02-22 | Syntex Corp | Preparation of 21-chloro steroids |
| US3992422A (en) * | 1975-08-14 | 1976-11-16 | Schering Corporation | Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes |
-
1976
- 1976-09-29 LU LU75903A patent/LU75903A1/xx unknown
- 1976-12-09 CH CH1549976A patent/CH624967A5/de not_active IP Right Cessation
-
1977
- 1977-06-08 SE SE7706673A patent/SE436751B/xx not_active IP Right Cessation
- 1977-06-09 DK DK256977A patent/DK146017C/da not_active IP Right Cessation
- 1977-09-14 NL NL7710089A patent/NL7710089A/xx not_active Application Discontinuation
- 1977-09-24 DE DE2743069A patent/DE2743069C2/de not_active Expired
- 1977-09-26 CH CH1172177A patent/CH632279A5/de not_active IP Right Cessation
- 1977-09-27 FR FR7729043A patent/FR2366311A1/fr active Granted
- 1977-09-27 DD DD7700201226A patent/DD133150A5/xx unknown
- 1977-09-27 CY CY1178A patent/CY1178A/xx unknown
- 1977-09-27 CA CA287,560A patent/CA1101410A/en not_active Expired
- 1977-09-27 GB GB40131/77A patent/GB1563638A/en not_active Expired
- 1977-09-27 AU AU29148/77A patent/AU514200B2/en not_active Expired
- 1977-09-28 HU HU77CI1774A patent/HU175218B/hu unknown
- 1977-09-28 AT AT0691077A patent/AT363197B/de not_active IP Right Cessation
- 1977-09-28 IE IE1979/77A patent/IE46047B1/en not_active IP Right Cessation
- 1977-09-28 ZA ZA00775800A patent/ZA775800B/xx unknown
- 1977-09-28 BE BE181243A patent/BE859120A/xx not_active IP Right Cessation
- 1977-09-28 IL IL53012A patent/IL53012A/xx unknown
- 1977-09-29 ES ES462763A patent/ES462763A1/es not_active Expired
- 1977-09-29 JP JP11619377A patent/JPS5356652A/ja active Granted
-
1979
- 1979-02-28 AT AT0151279A patent/AT363202B/de not_active IP Right Cessation
- 1979-02-28 AT AT0151379A patent/AT363203B/de not_active IP Right Cessation
-
1980
- 1980-11-18 CH CH853980A patent/CH625810A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853880A patent/CH625809A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853780A patent/CH625808A5/de not_active IP Right Cessation
-
1981
- 1981-10-26 CH CH683081A patent/CH631998A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683281A patent/CH632000A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683181A patent/CH631999A5/de not_active IP Right Cessation
-
1982
- 1982-01-06 CH CH4682A patent/CH632521A5/de not_active IP Right Cessation
-
1983
- 1983-01-20 SG SG33/83A patent/SG3383G/en unknown
- 1983-01-21 KE KE3258A patent/KE3258A/xx unknown
- 1983-05-19 HK HK166/83A patent/HK16683A/en not_active IP Right Cessation
-
1984
- 1984-12-30 MY MY92/84A patent/MY8400092A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |