DK142498B - Analogifremgangsmåde til fremstilling af benzopyridoazepinderivater. - Google Patents

Analogifremgangsmåde til fremstilling af benzopyridoazepinderivater. Download PDF

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Publication number
DK142498B
DK142498B DK142676AA DK142676A DK142498B DK 142498 B DK142498 B DK 142498B DK 142676A A DK142676A A DK 142676AA DK 142676 A DK142676 A DK 142676A DK 142498 B DK142498 B DK 142498B
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DK
Denmark
Prior art keywords
methyl
pyrido
azepine
benzo
compound
Prior art date
Application number
DK142676AA
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Danish (da)
English (en)
Other versions
DK142676A (tr
DK142498C (tr
Inventor
Willem Jacob Van Der Burg
Original Assignee
Akzo Nv
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19823518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK142498(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK142676A publication Critical patent/DK142676A/da
Publication of DK142498B publication Critical patent/DK142498B/da
Application granted granted Critical
Publication of DK142498C publication Critical patent/DK142498C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK142676AA 1975-04-05 1976-03-30 Analogifremgangsmåde til fremstilling af benzopyridoazepinderivater. DK142498B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NLAANVRAGE7504075,A NL189199C (nl) 1975-04-05 1975-04-05 Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
NL7504075 1975-04-05

Publications (3)

Publication Number Publication Date
DK142676A DK142676A (tr) 1976-10-06
DK142498B true DK142498B (da) 1980-11-10
DK142498C DK142498C (tr) 1981-07-06

Family

ID=19823518

Family Applications (1)

Application Number Title Priority Date Filing Date
DK142676AA DK142498B (da) 1975-04-05 1976-03-30 Analogifremgangsmåde til fremstilling af benzopyridoazepinderivater.

Country Status (17)

Country Link
US (1) US4062848A (tr)
JP (1) JPS5942678B2 (tr)
BE (1) BE840362A (tr)
CA (1) CA1076571A (tr)
CH (1) CH622261A5 (tr)
DE (1) DE2614406A1 (tr)
DK (1) DK142498B (tr)
ES (2) ES446634A1 (tr)
FI (1) FI62087C (tr)
FR (1) FR2305986A1 (tr)
GB (1) GB1543171A (tr)
HU (1) HU179401B (tr)
IE (1) IE42969B1 (tr)
LU (1) LU74680A1 (tr)
NL (2) NL189199C (tr)
SE (1) SE422941B (tr)
ZA (1) ZA761756B (tr)

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JPH055746Y2 (tr) * 1988-04-27 1993-02-15
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AU781221B2 (en) * 1999-04-19 2005-05-12 Teva Pharmaceutical Industries Ltd. Novel synthesis and crystallization of piperazine ring-containing compounds
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US6545149B2 (en) 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
AU777105B2 (en) 1999-04-19 2004-09-30 Teva Pharmaceutical Industries Ltd. Novel synthesis of piperazine ring
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AU6019900A (en) 1999-11-24 2001-06-04 Sumika Fine Chemicals Co., Ltd. Anhydrous mirtazapine crystals and process for producing the same
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DK1257278T3 (da) 2000-02-11 2006-06-12 Akzo Nobel Nv Anvendelse af mirtazapin til behandling af sövnforstyrrelser
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US6660730B2 (en) 2000-11-27 2003-12-09 Sumika Fine Chemicals Co., Ltd. Anhydrous mirtazapine and process for preparing the same
US6399310B1 (en) 2001-02-12 2002-06-04 Akzo Nobel N.V. Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
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CN103509020A (zh) * 2013-10-21 2014-01-15 山东鲁药制药有限公司 一种米氮平的合成方法
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KR102540021B1 (ko) 2020-12-02 2023-06-07 (주)유케이케미팜 대량 생산에 적합한 미르타자핀의 제조방법

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Also Published As

Publication number Publication date
GB1543171A (en) 1979-03-28
NL189199B (nl) 1992-09-01
SE7603931L (sv) 1976-10-06
NL7504075A (nl) 1976-10-07
BE840362A (fr) 1976-10-04
ES459348A1 (es) 1978-03-16
DK142676A (tr) 1976-10-06
LU74680A1 (tr) 1976-11-11
NL940007I2 (nl) 1994-10-17
CA1076571A (en) 1980-04-29
IE42969L (en) 1976-10-05
FR2305986B1 (tr) 1980-06-13
DK142498C (tr) 1981-07-06
DE2614406A1 (de) 1976-10-14
ES446634A1 (es) 1977-11-01
AU1236176A (en) 1977-09-29
US4062848A (en) 1977-12-13
NL189199C (nl) 1993-02-01
HU179401B (en) 1982-10-28
FI760884A (tr) 1976-10-06
JPS51122099A (en) 1976-10-25
FI62087B (fi) 1982-07-30
IE42969B1 (en) 1980-11-19
FI62087C (fi) 1982-11-10
ZA761756B (en) 1977-03-30
SE422941B (sv) 1982-04-05
DE2614406C2 (tr) 1992-02-20
FR2305986A1 (fr) 1976-10-29
JPS5942678B2 (ja) 1984-10-16
NL940007I1 (nl) 1994-06-01
CH622261A5 (tr) 1981-03-31

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