DK1307446T3 - Perfluoralkylholdige komplekser med sukkerrester, fremgangsmåde til deres fremstilling og deres anvendelse - Google Patents
Perfluoralkylholdige komplekser med sukkerrester, fremgangsmåde til deres fremstilling og deres anvendelseInfo
- Publication number
- DK1307446T3 DK1307446T3 DK01969481T DK01969481T DK1307446T3 DK 1307446 T3 DK1307446 T3 DK 1307446T3 DK 01969481 T DK01969481 T DK 01969481T DK 01969481 T DK01969481 T DK 01969481T DK 1307446 T3 DK1307446 T3 DK 1307446T3
- Authority
- DK
- Denmark
- Prior art keywords
- perfluoroalkyl
- preparation
- sugar residues
- containing complexes
- complexes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10040381A DE10040381C1 (de) | 2000-08-11 | 2000-08-11 | Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung |
PCT/EP2001/008499 WO2002014309A1 (fr) | 2000-08-11 | 2001-07-23 | Complexes perfluoroalkyles a residus saccharides, leur procede de fabrication et leur utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1307446T3 true DK1307446T3 (da) | 2005-08-15 |
Family
ID=7652861
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01969481T DK1307446T3 (da) | 2000-08-11 | 2001-07-23 | Perfluoralkylholdige komplekser med sukkerrester, fremgangsmåde til deres fremstilling og deres anvendelse |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP1307446B1 (fr) |
JP (1) | JP2004506631A (fr) |
KR (1) | KR100820387B1 (fr) |
CN (1) | CN1249058C (fr) |
AR (1) | AR035579A1 (fr) |
AT (1) | ATE293623T1 (fr) |
AU (2) | AU2001289729B2 (fr) |
BG (1) | BG107540A (fr) |
BR (1) | BR0113192A (fr) |
CA (1) | CA2418790A1 (fr) |
CZ (1) | CZ2003340A3 (fr) |
DE (2) | DE10040381C1 (fr) |
DK (1) | DK1307446T3 (fr) |
EE (1) | EE200300059A (fr) |
ES (1) | ES2240517T3 (fr) |
HK (1) | HK1062016A1 (fr) |
HR (1) | HRP20030172A2 (fr) |
HU (1) | HUP0300744A3 (fr) |
IL (1) | IL154328A0 (fr) |
MX (1) | MXPA03001285A (fr) |
NO (1) | NO20030648L (fr) |
NZ (1) | NZ524079A (fr) |
PL (1) | PL360359A1 (fr) |
PT (1) | PT1307446E (fr) |
RU (1) | RU2280644C2 (fr) |
SK (1) | SK1542003A3 (fr) |
TW (1) | TWI243170B (fr) |
UA (1) | UA75364C2 (fr) |
WO (1) | WO2002014309A1 (fr) |
YU (1) | YU10403A (fr) |
ZA (1) | ZA200301948B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19948651B4 (de) * | 1999-09-29 | 2006-10-05 | Schering Ag | Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung |
US7344704B2 (en) | 2002-07-10 | 2008-03-18 | Schering Ag | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi |
DE10231799B4 (de) * | 2002-07-10 | 2006-10-05 | Schering Ag | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben |
DE10260372B4 (de) | 2002-12-13 | 2007-01-04 | Schering Ag | Kernspintomographievorrichtung und Verfahren zur ortsaufgelösten Bilddarstellung |
EP1904462A2 (fr) * | 2005-07-15 | 2008-04-02 | Bayer Schering Pharma Aktiengesellschaft | Complexes perfluoro-alkyles, leur procede de production et leur utilisation |
DE102006049821A1 (de) | 2006-10-18 | 2008-04-24 | Bayer Schering Pharma Aktiengesellschaft | Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung |
BRPI0717395A2 (pt) * | 2006-10-25 | 2013-10-15 | Koninkl Philips Electronics Nv | Composto para diagnosticar câncer de próstata em um indivíduo humano ou animal, composição farmacêutica, e, uso de um composto ou uma composição |
DE102008024976A1 (de) | 2008-05-23 | 2009-12-17 | Marvis Technologies Gmbh | Medizinisches Instrument |
JP2011190183A (ja) * | 2010-03-11 | 2011-09-29 | Noguchi Institute | フルオラス化糖結合型クラウンエーテル誘導体 |
EP2450067A1 (fr) | 2010-10-18 | 2012-05-09 | MaRVis Technologies GmbH | Dispositif médical |
EP2484388A1 (fr) | 2011-02-05 | 2012-08-08 | MaRVis Technologies GmbH | Dispositif médical implantable ou insérable détectable par IRM doté d'un revêtement comportant des ions paramagnétiques et son procédé de préparation |
EP2692365A1 (fr) | 2012-08-03 | 2014-02-05 | MaRVis Medical GmbH | Dispositif médical implantable ou insérable détectable par IRM doté dýun revêtement comportant des ions paramagnétiques et son procédé de préparation |
EP3101012A1 (fr) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | Nouveaux composés de chélate de gadolinium pour une utilisation dans l'imagerie par résonance magnétique |
US10975060B2 (en) | 2016-11-28 | 2021-04-13 | Bayer Pharma Aktiengesellschaft | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging |
CN113164628A (zh) | 2018-11-23 | 2021-07-23 | 拜耳股份有限公司 | 造影介质制剂及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5707604A (en) * | 1986-11-18 | 1998-01-13 | Access Pharmaceuticals, Inc. | Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles |
AU623901B2 (en) * | 1988-01-26 | 1992-05-28 | Nycomed As | Paramagnetic compounds comprising chelating moiety, linker group macro molecule and paramagnetic metal |
EP0497926B1 (fr) * | 1989-10-23 | 1998-06-03 | Nycomed Salutar, Inc. | Agents chelateurs metalliques multi-sites |
US5330743A (en) * | 1992-11-12 | 1994-07-19 | Magnetic Research, Inc. | Aminosaccharide contrast agents for magnetic resonance images |
ZA958789B (en) * | 1994-10-21 | 1996-05-29 | Nihon Mediphysics Co Ltd | Diagnostic imaging agent |
DE19603033A1 (de) * | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
DE19728954C1 (de) * | 1997-06-30 | 1999-04-22 | Schering Ag | Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung |
DE19729013A1 (de) * | 1997-07-03 | 1999-02-04 | Schering Ag | Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
DE19744004C1 (de) * | 1997-09-26 | 1999-07-22 | Schering Ag | Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging |
DE19758105A1 (de) * | 1997-12-18 | 1999-06-24 | Schering Ag | Dendritische Polymer-Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung |
DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
DE19948651B4 (de) * | 1999-09-29 | 2006-10-05 | Schering Ag | Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung |
-
2000
- 2000-08-11 DE DE10040381A patent/DE10040381C1/de not_active Expired - Fee Related
-
2001
- 2001-07-23 CA CA002418790A patent/CA2418790A1/fr not_active Abandoned
- 2001-07-23 PL PL01360359A patent/PL360359A1/xx not_active Application Discontinuation
- 2001-07-23 BR BR0113192-3A patent/BR0113192A/pt not_active IP Right Cessation
- 2001-07-23 IL IL15432801A patent/IL154328A0/xx unknown
- 2001-07-23 DK DK01969481T patent/DK1307446T3/da active
- 2001-07-23 DE DE50105965T patent/DE50105965D1/de not_active Expired - Fee Related
- 2001-07-23 SK SK154-2003A patent/SK1542003A3/sk unknown
- 2001-07-23 YU YU10403A patent/YU10403A/sh unknown
- 2001-07-23 ES ES01969481T patent/ES2240517T3/es not_active Expired - Lifetime
- 2001-07-23 CN CNB018171109A patent/CN1249058C/zh not_active Expired - Fee Related
- 2001-07-23 JP JP2002519449A patent/JP2004506631A/ja active Pending
- 2001-07-23 CZ CZ2003340A patent/CZ2003340A3/cs unknown
- 2001-07-23 AT AT01969481T patent/ATE293623T1/de not_active IP Right Cessation
- 2001-07-23 AU AU2001289729A patent/AU2001289729B2/en not_active Ceased
- 2001-07-23 EE EEP200300059A patent/EE200300059A/xx unknown
- 2001-07-23 HU HU0300744A patent/HUP0300744A3/hu unknown
- 2001-07-23 EP EP01969481A patent/EP1307446B1/fr not_active Expired - Lifetime
- 2001-07-23 UA UA2003032069A patent/UA75364C2/uk unknown
- 2001-07-23 RU RU2003105815/04A patent/RU2280644C2/ru not_active IP Right Cessation
- 2001-07-23 AU AU8972901A patent/AU8972901A/xx active Pending
- 2001-07-23 PT PT01969481T patent/PT1307446E/pt unknown
- 2001-07-23 NZ NZ524079A patent/NZ524079A/en unknown
- 2001-07-23 WO PCT/EP2001/008499 patent/WO2002014309A1/fr active IP Right Grant
- 2001-07-23 MX MXPA03001285A patent/MXPA03001285A/es active IP Right Grant
- 2001-07-23 KR KR1020037002021A patent/KR100820387B1/ko not_active IP Right Cessation
- 2001-08-10 AR ARP010103831A patent/AR035579A1/es unknown
- 2001-08-10 TW TW090119623A patent/TWI243170B/zh not_active IP Right Cessation
-
2003
- 2003-02-07 BG BG107540A patent/BG107540A/bg unknown
- 2003-02-10 NO NO20030648A patent/NO20030648L/no not_active Application Discontinuation
- 2003-03-10 ZA ZA200301948A patent/ZA200301948B/en unknown
- 2003-03-10 HR HR20030172A patent/HRP20030172A2/hr not_active Application Discontinuation
-
2004
- 2004-07-13 HK HK04105095A patent/HK1062016A1/xx not_active IP Right Cessation
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