DK1220849T3 - Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering heraf - Google Patents
Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering herafInfo
- Publication number
- DK1220849T3 DK1220849T3 DK00966462T DK00966462T DK1220849T3 DK 1220849 T3 DK1220849 T3 DK 1220849T3 DK 00966462 T DK00966462 T DK 00966462T DK 00966462 T DK00966462 T DK 00966462T DK 1220849 T3 DK1220849 T3 DK 1220849T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- stabilization method
- bicyclic compounds
- bicyclic
- compounds
- Prior art date
Links
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15954999P | 1999-10-15 | 1999-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1220849T3 true DK1220849T3 (da) | 2004-09-27 |
Family
ID=22573018
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00966462T DK1220849T3 (da) | 1999-10-15 | 2000-10-13 | Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering heraf |
DK04005836T DK1426361T4 (en) | 1999-10-15 | 2000-10-13 | Novel compounds containing a bi-cyclic compound and a glyceride |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04005836T DK1426361T4 (en) | 1999-10-15 | 2000-10-13 | Novel compounds containing a bi-cyclic compound and a glyceride |
Country Status (26)
Country | Link |
---|---|
US (5) | US6583174B1 (hu) |
EP (2) | EP1220849B1 (hu) |
JP (2) | JP4332316B2 (hu) |
KR (1) | KR100830061B1 (hu) |
CN (1) | CN1268623C (hu) |
AR (3) | AR026046A1 (hu) |
AT (2) | ATE267189T1 (hu) |
AU (2) | AU780342B2 (hu) |
BR (1) | BRPI0014869B8 (hu) |
CA (1) | CA2385732C (hu) |
CZ (1) | CZ303625B6 (hu) |
DE (2) | DE60039727D1 (hu) |
DK (2) | DK1220849T3 (hu) |
ES (2) | ES2309410T5 (hu) |
HK (2) | HK1066792A1 (hu) |
HU (2) | HU230484B1 (hu) |
IL (2) | IL148803A0 (hu) |
MX (1) | MXPA02003756A (hu) |
NO (1) | NO330258B1 (hu) |
NZ (1) | NZ518020A (hu) |
PT (2) | PT1426361E (hu) |
RU (1) | RU2695274C3 (hu) |
TR (1) | TR200201032T2 (hu) |
TW (1) | TWI281918B (hu) |
WO (1) | WO2001027099A2 (hu) |
ZA (1) | ZA200202312B (hu) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1220849T3 (da) * | 1999-10-15 | 2004-09-27 | Sucampo Ag | Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering heraf |
US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
TWI331920B (en) | 2001-11-14 | 2010-10-21 | Sucampo Ag | Unit dosage form for relieving or treating constipation in human patients |
FR2842810B1 (fr) * | 2002-07-25 | 2006-01-27 | Inst Nat Sciences Appliq | Nouveaux composes gem difluores, leur procedes de preparation et leurs applications. |
NZ539582A (en) * | 2002-10-23 | 2007-07-27 | Sucampo Ag | Prostaglandin compounds for the treatment of obesity |
TWI336254B (en) * | 2002-12-27 | 2011-01-21 | Sucampo Ag | Pharmaceutical composition for treating abdominal discomfort |
ATE489096T1 (de) * | 2003-07-03 | 2010-12-15 | Sucampo Ag | Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner |
TWI348386B (en) * | 2003-08-12 | 2011-09-11 | R Tech Ueno Ltd | Composition and method for promoting hair growth |
TWI387454B (zh) | 2004-09-02 | 2013-03-01 | Sucampo Ag | 治療胃腸道疾病之方法及組成物 |
RU2468800C2 (ru) * | 2005-04-12 | 2012-12-10 | Сукампо Аг | Комбинированное применение производного простагландина и ингибитора протонового насоса для лечения желудочно-кишечных заболеваний |
KR101393944B1 (ko) | 2006-01-24 | 2014-05-12 | 수캄포 아게 | 연질-젤라틴 캡슐 제형물 |
NZ570190A (en) | 2006-01-24 | 2011-03-31 | Sucampo Ag | Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound |
KR101353187B1 (ko) * | 2006-02-07 | 2014-01-17 | 수캄포 아게 | 프로스타글란딘 유도체의 제조 방법 |
US20090030072A1 (en) | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
US20090012165A1 (en) | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
CA2691995C (en) * | 2007-07-19 | 2016-04-26 | R-Tech Ueno, Ltd. | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound |
US20090082442A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched lubiprostone |
CN101318948B (zh) * | 2008-04-01 | 2011-04-27 | 上海天伟生物制药有限公司 | 鲁比前列酮晶体、其制备方法及用途 |
US8569279B2 (en) * | 2009-05-27 | 2013-10-29 | Sucampo Ag | Method for modulating claudin mediated functions |
US20110034424A1 (en) * | 2009-06-30 | 2011-02-10 | Sucampo Ag | Method for the long term nsaid use |
HUE028874T2 (hu) | 2009-07-28 | 2017-01-30 | Ono Pharmaceutical Co | Biciklikus vegyület és annak felhasználása orvosi célokra |
BR112012006069A8 (pt) * | 2009-09-18 | 2017-10-10 | Adolor Corp | Método para tratar ou prevenir constipação induzida e disfunção intestinal induzida por opióide em um humano, e, uso de uma quantidade terapeuticamente efetiva de composto |
US8940790B2 (en) | 2009-11-03 | 2015-01-27 | Bernard Charles Sherman | Stable pharmaceutical formulations comprising lubiprostone |
US9150537B2 (en) | 2011-01-27 | 2015-10-06 | Ono Pharmaceutical Co., Ltd. | Bicyclic compound and use thereof for medical purposes |
WO2012102357A1 (ja) | 2011-01-27 | 2012-08-02 | 小野薬品工業株式会社 | 二環式化合物およびその医薬用途 |
WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
EP3277274B1 (en) | 2015-04-01 | 2024-06-12 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
WO2018003945A1 (ja) | 2016-06-30 | 2018-01-04 | 小野薬品工業株式会社 | 二環式化合物の製造方法 |
WO2018065826A1 (en) | 2016-10-06 | 2018-04-12 | Sucampo Ag | Multilayer beads for pharmaceutical use |
WO2019221215A1 (ja) * | 2018-05-18 | 2019-11-21 | ニプロ株式会社 | ルビプロストン含有粒子状医薬組成物 |
JP7518661B2 (ja) | 2020-05-14 | 2024-07-18 | 沢井製薬株式会社 | ルビプロストン含有整粒物、ルビプロストン含有錠剤およびそれらの製造方法 |
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CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
US5981607A (en) | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
DK1220849T3 (da) * | 1999-10-15 | 2004-09-27 | Sucampo Ag | Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering heraf |
US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
JP4210631B2 (ja) | 2004-06-24 | 2009-01-21 | 株式会社日立製作所 | ブレーキ制御装置 |
-
2000
- 2000-10-13 DK DK00966462T patent/DK1220849T3/da active
- 2000-10-13 HU HU1300369A patent/HU230484B1/hu not_active IP Right Cessation
- 2000-10-13 ES ES04005836.4T patent/ES2309410T5/es not_active Expired - Lifetime
- 2000-10-13 DE DE60039727T patent/DE60039727D1/de not_active Expired - Lifetime
- 2000-10-13 PT PT04005836T patent/PT1426361E/pt unknown
- 2000-10-13 ES ES00966462T patent/ES2221859T3/es not_active Expired - Lifetime
- 2000-10-13 CZ CZ20021037A patent/CZ303625B6/cs not_active IP Right Cessation
- 2000-10-13 DE DE60010913T patent/DE60010913T2/de not_active Expired - Lifetime
- 2000-10-13 DK DK04005836T patent/DK1426361T4/en active
- 2000-10-13 TR TR2002/01032T patent/TR200201032T2/xx unknown
- 2000-10-13 RU RU2002112984A patent/RU2695274C3/ru active Protection Beyond IP Right Term
- 2000-10-13 KR KR1020027004709A patent/KR100830061B1/ko active Protection Beyond IP Right Term
- 2000-10-13 AT AT00966462T patent/ATE267189T1/de active
- 2000-10-13 PT PT00966462T patent/PT1220849E/pt unknown
- 2000-10-13 EP EP00966462A patent/EP1220849B1/en not_active Expired - Lifetime
- 2000-10-13 MX MXPA02003756A patent/MXPA02003756A/es active IP Right Grant
- 2000-10-13 HU HU0203746A patent/HU229547B1/hu not_active IP Right Cessation
- 2000-10-13 BR BRPI0014869A patent/BRPI0014869B8/pt not_active IP Right Cessation
- 2000-10-13 AT AT04005836T patent/ATE402925T2/de active
- 2000-10-13 WO PCT/JP2000/007109 patent/WO2001027099A2/en active IP Right Grant
- 2000-10-13 TW TW089121423A patent/TWI281918B/zh not_active IP Right Cessation
- 2000-10-13 AU AU76856/00A patent/AU780342B2/en not_active Expired
- 2000-10-13 JP JP2001530318A patent/JP4332316B2/ja not_active Expired - Lifetime
- 2000-10-13 CN CNB008143137A patent/CN1268623C/zh not_active Ceased
- 2000-10-13 IL IL14880300A patent/IL148803A0/xx active IP Right Grant
- 2000-10-13 CA CA002385732A patent/CA2385732C/en not_active Expired - Lifetime
- 2000-10-13 AR ARP000105407A patent/AR026046A1/es not_active Application Discontinuation
- 2000-10-13 NZ NZ518020A patent/NZ518020A/en not_active IP Right Cessation
- 2000-10-13 EP EP04005836.4A patent/EP1426361B2/en not_active Expired - Lifetime
- 2000-10-16 US US09/688,351 patent/US6583174B1/en not_active Expired - Lifetime
-
2002
- 2002-03-21 IL IL148803A patent/IL148803A/en unknown
- 2002-03-22 ZA ZA200202312A patent/ZA200202312B/en unknown
- 2002-04-12 NO NO20021736A patent/NO330258B1/no not_active IP Right Cessation
- 2002-10-07 HK HK04109640.1A patent/HK1066792A1/xx not_active IP Right Cessation
- 2002-10-07 HK HK02107337.5A patent/HK1045693B/zh not_active IP Right Cessation
-
2003
- 2003-03-10 US US10/383,581 patent/US7417067B2/en not_active Expired - Lifetime
-
2004
- 2004-12-24 AU AU2004242503A patent/AU2004242503B2/en not_active Expired
-
2008
- 2008-06-23 US US12/144,000 patent/US8088934B2/en not_active Expired - Lifetime
-
2009
- 2009-05-25 JP JP2009125293A patent/JP2009235079A/ja active Pending
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2011
- 2011-11-04 US US13/289,386 patent/US8097649B1/en not_active Expired - Lifetime
- 2011-12-27 US US13/337,391 patent/US20120095090A1/en not_active Abandoned
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2013
- 2013-01-30 AR ARP130100275A patent/AR089848A2/es not_active Application Discontinuation
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2017
- 2017-08-16 AR ARP170102288A patent/AR109354A2/es unknown
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